Media Centre - IARC News

2012

Molecular Epidemiology: Principles and Practices

IARC Scientific Publication No 163

Edited by Nathaniel Rothman, Pierre Hainaut, Paul Schulte, Martyn Smith, Paolo Boffetta and Frederica Perera.
01/04/2012 -
Molecular Epidemiology: Principles and Practices ISBN-13 9789283221630
ISBN-10 928322163X
Price CHF 125.00 / US$ 150.00
Developing countries: CHF 87.50

Order at WHO Press 

Molecular Epidemiology, as a new concept, came under the limelight with the publication of "Molecular Epidemiology: Principles and Practice" by Schulte and Perera in 1993, which established a framework to integrate the rapid advances being made in the development of a wide range of biomarkers with the established methodology of classic epidemiological study design and analysis to increase our understanding of the mechanisms of disease in populations.

Almost two decades later, this concept has flourished into an exceptionally wide and diverse field that has profoundly changed our understanding of the causes of human diseases. Molecular Epidemiology has taken advantage of the emergence of technological advances collectively identified as "-omics" (genomics, transcriptomics, proteomic , metabonomics) and their usage in epidemiological studies has heralded a revolution in the design implementation, and interpretation of studies on disease causation. Not the least, Molecular Epidemiology has brought together scientists of all disciplines to interact into very large, often multi-national networks, fostering consortia that have the size and power to addresss diseases as a global challenge.

This book captures these fascinating developments and provide an extended, forward-looking vision of the principles, practice and impact of Molecular Epidemiology. Written and coordinated by world leaders in the field, the book covers in a systematic way the major conceptual advances, with a strong emphasis on study design and on how to incorporate biomarker studies into epidemiology practice. While providing a cornerstone for specialists, the book is also a teaching and training manual for public health, biology and medical students at the undergraduate, graduate, and post-graduate levels. With its strong insistence on interdisciplinarity and its focus on translating complex concepts into information that can be shared across the borders of scientific disciplines, the book will be a door-opener for researchers whose work is being attracted by the potent magnet of Molecular Epidemiology.