Media Centre - IARC NEWS

2016


Molecular Epidemiology: Principles and Practices – now available in PDF format
05/12/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Molecular Epidemiology: Principles and Practices is now available free in PDF format. The book covers the major conceptual advances in this field, with a strong emphasis on study design and on how to incorporate biomarker studies into epidemiology practice. It is a resource for specialists and a useful teaching and training manual for students. The book is also available for purchase in print format.

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2017 IARC Summer School in Cancer Epidemiology – Call for applications now open
30/11/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the call for applications is now open for the 2017 IARC Summer School in Cancer Epidemiology, to be held at IARC in Lyon on 19 June–7 July 2017. Three modules will be offered: "Cancer Survival Methods for Cancer Registries", "Implementing Cancer Prevention and Early Detection", and "Introduction to Cancer Epidemiology". The deadline for applications is 20 January 2017.

More information , Online application form
IARC Postdoctoral Opportunities - Section of Mechanisms of Carcinogenesis/Epigenetics Group
24/11/2016 -
A postdoctoral opportunity is immediately available within the Epigenetics Group to apply state-of-the-art molecular/cell biology and new functional genomic tools for mechanistic studies focusing on functionally important epigenetic “driver” genes (“epidrivers”) and associated molecular pathways.

Deadline: 31 January 2017

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In utero exposure to radiation and haematological malignancies: pooled analysis of Southern Urals cohort
22/11/2016 -
The results of a study led by researchers from the IARC Section of Environment and Radiation analysing in utero exposure to low-dose ionizing radiation in the Southern Urals, Russian Federation, and its link to the lifetime risk of haematological malignancies have been published in the British Journal of Cancer. The study is based on cohorts in the Southern Urals of people exposed in utero to ionizing radiation, because their mothers either worked at a large nuclear facility or lived in areas along the Techa River contaminated by nuclear accidents and nuclear waste dumping.

Schüz J, Deltour I, Krestinina LY, Tsareva YV, Tolstykh EI, Sokolnikov ME, Akleyev AV
In utero exposure to radiation and haematological malignancies: pooled analysis of Southern Urals cohort
Br J Cancer, Published online 17 November 2016;
http://dx.doi.org/10.1038/bjc.2016.373

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IARC/NCI Tumour Seminar: Oesophageal squamous cell cancer
22/11/2016 -
Materials are now available from the International Agency for Research on Cancer (IARC)/United States National Cancer Institute (NCI) Tumour Seminar meeting on the topic “Difficult questions in squamous cell oesophageal cancer research”, held at NCI on 29–30 September 2016. The materials available include the programme of the meeting and PDF files of presentation slides.

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Umberto Veronesi (28 November 1925 – 8 November 2016)
10/11/2016 -
The International Agency for Research on Cancer (IARC) is saddened by the passing of Professor Umberto Veronesi, who died on Tuesday 8 November 2016 in Milan, Italy. Our deepest sympathy is with his family.

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IARC scientist receives Champion of Environmental Health Research Award
02/11/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Dr Kurt Straif, Head of the Section of IARC Monographs, is one of 12 recipients of the first-ever Champion of Environmental Health Research Award. The awards are presented by the United States National Institute of Environmental Health Sciences (NIEHS) to recognize outstanding researchers, leaders, and communicators who have contributed to the NIEHS mission of discovering how the environment affects people in order to promote healthier lives. The awards were presented on 1 November at the NIEHS campus, to celebrate the institute's 50th anniversary.

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IARC research featured at UICC World Cancer Congress 2016
31/10/2016 -
The International Agency for Research on Cancer (IARC) will feature some of its key research results at the UICC World Cancer Congress in Paris this week. IARC scientists will participate in debates, workshops, symposia, and discussion panels on a wide variety of topics related to cancer prevention. Video interviews are available with selected IARC scientists who will be presenting their research at the World Cancer Congress.

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Breast Cancer Awareness Month – breast cancer survival in sub-Saharan Africa
28/10/2016 -
This fifth report in a series to mark Breast Cancer Awareness Month 2016 focuses on a study of breast cancer survival in sub-Saharan Africa. A recently published article describes the African Breast Cancer - Disparities in Outcomes (ABC-DO) study, which is led by researchers from the International Agency for Research on Cancer (IARC). The article presents the study protocol, which includes using a mobile health (mHealth) study management system. Dr Valerie McCormack and Dr Fiona McKenzie, scientists in the IARC Section of Environment and Radiation and the ABC-DO IARC study leaders, provide more information about the study.
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Breast Cancer Awareness Month – alcohol consumption and breast cancer
28/10/2016 -
This fourth report in a series to mark Breast Cancer Awareness Month 2016 focuses on the association between alcohol consumption and breast cancer. A recent systematic review, led by researchers from the International Agency for Research on Cancer (IARC), looks at the global burden of breast cancer incidence and mortality attributable to alcohol consumption. The article also estimates the increase in breast cancer risk associated with drinking alcohol, especially low levels of alcohol. Dr Kevin Shield, lead author of the paper, provides more details about the research.

http://www.iarc.fr/en/media-centre/multimedia/audiovideos/index.php , Read article
IARC responds to Reuters article
26/10/2016 -

An article from Reuters (published on 25 October 2016) on the subject of access to documents concerning the IARC Monographs Programme severely distorts the motives of the International Agency for Research on Cancer (IARC). IARC wishes to make it clear that its motivation is to ensure that scientists are free to openly and critically debate the scientific evidence on whether an agent causes cancer in humans, in the best interests of public health worldwide.

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Breast Cancer Awareness Month – Handbook on breast cancer screening
26/10/2016 -
This second report in a series to mark Breast Cancer Awareness Month focuses on the recently published Handbook on Breast Cancer Screening. For Volume 15 of the Handbooks, a Working Group of 29 independent experts convened by the International Agency for Research on Cancer (IARC) reviewed the scientific evidence and assessed the cancer-preventive and adverse effects of various methods of screening for breast cancer. Dr Béatrice Lauby-Secretan, who leads the IARC Handbooks series, discusses the evaluations of the Handbook on Breast Cancer Screening.

Watch video , See IARC Handbook of Cancer Prevention Volume 15
Breast Cancer Awareness Month – benefits of breast cancer awareness
25/10/2016 -
This third report in a series to mark Breast Cancer Awareness Month 2016 focuses on the benefits of breast cancer awareness. Dr Rengaswamy Sankaranarayanan, Special Advisor on Cancer Control to the Director of the International Agency for Research on Cancer (IARC) and Head of the Screening Group in the IARC Section of Early Detection and Prevention, describes some of the concrete benefits that Breast Cancer Awareness Month has brought.

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Improving Public Health Through Mycotoxin Control – now available in PDF format
25/10/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Improving Public Health Through Mycotoxin Control is now available free in PDF format. This book aims to sensitize the international community to the mycotoxin problem in a format that is accessible to a wide audience and is useful to decision-makers across a broad spectrum of disciplines, including agriculture, public health, marketing, and economics. The book is also available for purchase in print format.

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IARC Monographs Volume 117: Evaluation of pentachlorophenol and some related compounds
24/10/2016 -
The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, has evaluated the carcinogenicity of five chemical agents: pentachlorophenol, 2,4,6-trichlorophenol, 3,3',4,4'-tetrachloroazobenzene, aldrin, and dieldrin. A summary of the evaluations has now been published in The Lancet Oncology. The detailed assessments will be published as Volume 117 of the IARC Monographs.

Guyton KZ, Loomis D, Grosse Y, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, et al.
Carcinogenicity of pentachlorophenol and some related compounds
Lancet Oncol, Published online 24 October 2016; http://dx.doi.org/10.1016/S1470-2045(16)30513-7

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Global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012
21/10/2016 -
Current cancer prevention initiatives for lip, oral cavity, and pharyngeal cancers are limited because of an absence of knowledge on the global incidence of these cancers by site. A new study, conducted by researchers from the International Agency for Research on Cancer (IARC), the American Cancer Society, and the United States National Cancer Institute, outlines and examines, for the first time, the number of new lip, oral cavity, and pharyngeal cancers worldwide by site, sex, and age. The study identifies stark regional variations in these cancers, hypothesized to be due to differences in exposures to carcinogens.

Shield KD, Ferlay J, Jemal A, Sankaranarayanan R, Chaturvedi AK, Bray F, et al.
The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012
CA Cancer J Clin, Published online 19 October 2016; http://dx.doi.org/10.3322/caac.21384

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IARC study identifies new genetic factors linked to HPV-related cancers
17/10/2016 -
A new large-scale genetic study of head and neck cancers shows why some individuals infected with human papillomavirus (HPV) may go on to develop oropharyngeal cancer while others do not. The study, published today in Nature Genetics, identifies seven new genetic loci (locations of a gene on a chromosome): one that is linked to oropharyngeal cancer and six that are associated with oral cavity cancer, thus providing new insights into the development of these diseases.

Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer
Lesseur C, Diergaarde B, Olshan AF, Wünsch-Filho V, Ness AR, Liu G, et al.
Nature Genetics. Published Online 17 October 2016; http://dx.doi.org/10.1038/ng.3685

Read article , Read IARC Press Release 249
IARC scientist receives 2016 Burkitt Medal
17/10/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Dr Paul Brennan, Head of IARC's Section of Genetics, was today awarded the 2016 Burkitt Medal at the 2016 International Cancer Conference, held at Trinity College Dublin, Ireland. Dr Brennan, who specializes in genetic epidemiology of lung cancer, head and neck cancers, kidney cancer, and lymphomas, presented the Burkitt Lecture, on “Cancer Prevention: from Denis Burkitt to the Human Genome Project”.

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Publication of IARC Handbooks of Cancer Prevention Volume 15: Breast Cancer Screening - in print and EPUB format
12/10/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Volume 15: Breast Cancer Screening of the IARC Handbooks of Cancer Prevention series is now available for purchase in print and EPUB format. The volume contains the detailed assessments of a Working Group of 29 experts from 16 countries who met at IARC on 11–18 November 2014 to assess the cancer-preventive and adverse effects of different methods of screening for breast cancer. This book is also available for purchase in PDF format.

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Cancer incidence and cancer control in Mongolia
11/10/2016 -
The National Cancer Registry of Mongolia, with support from the Global Initiative for Cancer Registry Development (GICR), has been improving its cancer data in accordance with international standards and guidelines. This new study, conducted by researchers from the International Agency for Research on Cancer (IARC) and the National Cancer Center of Mongolia, examines region-specific estimates of the scale and profile of cancer in Mongolia and discusses the underlying explanations from the major risk factors in operation.

Cancer incidence and cancer control in Mongolia: results from the National Cancer Registry 2008-12
Chimed T, Sandagdorj T, Znaor A, Laversanne M, Tseveen B, Genden P, Bray F
Int J Cancer. Accepted manuscript published online 7 October 2016;
http://onlinelibrary.wiley.com/doi/10.1002/ijc.30463/full

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IARC Postdoctoral Opportunities - Section of Infections/Infections and Cancer Epidemiology Group
10/10/2016 -
A postdoctoral opportunity is available within the Infections and Cancer Epidemiology Group starting in the early months of 2017. Candidates should have a good understanding of individual and population-level social determinants of cancer and interventions, and of aggregate macroeconomic indicators (such as HDI, GDP, etc.), along with a strong quantitative background.

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IARC marks Breast Cancer Awareness Month
03/10/2016 -
To mark Breast Cancer Awareness Month 2016, the International Agency for Research on Cancer (IARC) is presenting a series of weekly reports, each illustrating important new research and findings about breast cancer prevention. Interviews with the scientists behind the research will be posted on the IARC website and Twitter account. This week’s report provides an overview of the disease, with a GLOBOCAN Fact Sheet showing the latest available data, graphs, and maps for breast cancer incidence and mortality worldwide.
View figures

Read more , GLOBOCAN Fact Sheet
Cancer in Central and South America Project
03/10/2016 -
A series of 17 scientific articles coordinated by the International Agency for Research on Cancer (IARC) as part of the Cancer in Central and South America (CSA) Project is being published today as an open-access supplement issue of Cancer Epidemiology. The series provides a comprehensive analysis of recent cancer patterns in Central and South America, based on the most extensive collation of data on cancer incidence and mortality in the region to date. The articles can also be accessed on the IARC Global Cancer Observatory website, along with cancer profiles for 22 countries and further information on cancer etiology in the region. The CSA Project is a collaboration between IARC's Section of Cancer Surveillance, the Red de Institutos e Instituciones Nacionales de Cáncer (RINC), and cancer registries throughout the Central and South American region.

Cancer in Central and South America. Cancer Epidemiology Volume 44, Supplement 1, Pages S1–S178 (September 2016)

Read IARC Press Release 248, Spanish, Portuguese

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Senior Visiting Scientist Award 2016
26/09/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the recipient of the 2016 Senior Visiting Scientist Award is Professor Pär Stattin from the Department of Surgical Sciences, Uppsala University, Sweden, and the Department of Surgical and Perioperative Sciences, Department of Urology and Andrology, Umeå University, Sweden.

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Epigenetic signatures of cigarette smoking
23/09/2016 -
A new study involving almost 16,000 individuals from 16 cohorts, co-authored by researchers from the International Agency for Research on Cancer (IARC), shows that cigarette smoking has a broad impact on genome-wide methylation many years after smoking cessation. DNA methylation is one potential mechanism by which tobacco exposure predisposes to adverse health outcomes, such as cancers, osteoporosis, and lung and cardiovascular disorders. The study, published in the American Heart Association Rapid Access Journal Report, provides new insights into genes affected by smoking, which could improve understanding of smoking-related diseases. These epigenetic alterations could also serve as sensitive and stable markers of lifetime exposure to tobacco smoke.

Epigenetic signatures of cigarette smoking
Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, et al. Circulation: Cardiovascular Genetics Published Online 20 September 2016;
http://dx.doi.org/10.1161/CIRCGENETICS.116.001506

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IARC endorses World Declaration for Cancer Research
22/09/2016 -
The International Agency for Research on Cancer (IARC) has endorsed the World Declaration for Cancer Research and joined a global movement to promote research in order to improve survival rates and the quality of life of patients with cancer. The initiative, launched today in Madrid by the Spanish Association Against Cancer (AECC) and the AECC Scientific Foundation, is also supported by many other international cancer organizations, including the Union for International Cancer Control (UICC), the European Association for Cancer Research (EACR), the European Society for Medical Oncology (ESMO), the United States National Institutes of Health (NIH), Cancer Research UK (CRUK), the American Society of Clinical Oncology (ASCO), the Dutch Cancer Society (KWF-DCS), and the Italian Association for Cancer Research (AIRC).

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A global view on cancer incidence and national levels of the human development index
20/09/2016 -
A new study conducted by researchers from the International Agency for Research on Cancer (IARC) shows a strong positive relationship between overall cancer incidence and the Human Development Index (HDI) level. The report, published in the International Journal of Cancer, assessed cancer incidence for all cancers combined and 27 major types according to national HDI levels. Using GLOBOCAN data for 184 countries, age-standardized incidence rates were assessed by four HDI levels (low, medium, high, and very high).

A global view on cancer incidence and national levels of the human development index
Fidler MM, Soerjomataram I, Bray F
Int J Cancer 139(11):2436–46 (2016). http://dx.doi.org/10.1002/ijc.30382

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Guidelines for establishing cancer registries now available in Russian
16/09/2016 -
IARC Technical Publication No. 43, Planning and Developing Population-Based Cancer Registration in Low- and Middle-Income Settings, is now also available in Russian, in addition to English, French, and Spanish. It can be downloaded in PDF format free of charge. This book from the International Agency for Research on Cancer (IARC), the World Health Organization (WHO), and the International Association of Cancer Registries (IACR) provides essential guidance on key steps in planning and establishing a cancer registry, including accessing sources of information, monitoring data quality, and reporting results.

Download in Russian
WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart 4th edition
08/09/2016 -
IARC is delighted that the WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart (4th edition) has been Highly Commended in the Pathology category of the 2016 British Medical Association (BMA) Medical Book Awards. As part of the WHO series on histological and genetic typing of human tumours, this authoritative, concise reference book serves as an indispensable guide for oncologists and pathologists.

See the WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart (4th edition) , See the 2016 BMA Medical Book Awards
Videos from Opening Ceremony of IARC conference now available
29/08/2016 -
Videos recorded during the Opening Ceremony of the IARC 50th anniversary scientific conference, “Global Cancer: Occurrence, Causes, and Avenues to Prevention”, held in Lyon on 7–10 June 2016, are now available. The recordings include the presentations of IARC Director Dr Christopher P. Wild, Her Royal Highness Princess Dina Mired of Jordan, and Dr Douglas Lowy, Acting Director of the United States National Cancer Institute.

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IARC Handbooks of Cancer Prevention Volume 16: Body Fatness
25/08/2016 -
A Working Group of 21 independent international experts met at the International Agency for Research on Cancer (IARC) on 5–12 April 2016 to assess the cancer-preventive effects of the absence of excess body fatness. A summary of the evaluations has now been published in The New England Journal of Medicine. The detailed assessments will be published as Volume 16 of the IARC Handbooks of Cancer Prevention. Also available is a Q&A on the Handbooks Volume 16 evaluations.

Body fatness and cancer – viewpoint of the IARC Working Group
Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K.
N Engl J Med. Published Online 25 August 2016; http://dx.doi.org/10.1056/NEJMsr1606602

Read article , Read IARC Press Release 247
European Code Against Cancer website now available in all EU languages
24/08/2016 -
The 4th edition of the European Code Against Cancer is now available in all European Union languages. The Code provides 12 ways that individuals can reduce their risk of developing cancer, and is a joint project between the International Agency for Research on Cancer (IARC) and the European Commission. The website includes Questions and Answers that provide additional information about the Code’s recommendations and the different types of cancer they help to prevent.

Visit website
Preventable fractions of cervical cancer via effective screening in the Baltic and eastern European region
23/08/2016 -
A new study, led by researchers from the International Agency for Research on Cancer (IARC) and published in The Lancet Oncology, shows that effective screening programmes could prevent an epidemic of cervical cancer in several Baltic and eastern European countries. With the immediate launch of effective screening programmes, an estimated 180 000 new cases of cervical cancer could be prevented from 2017 to 2040 in six Baltic and eastern European countries.

Preventable fractions of cervical cancer via effective screening in six Baltic, central, and eastern European countries 2017–40: a population-based study
Vaccarella S, Franceschi S, Zaridze D, Poljak M, Veerus P, Plummer M, Bray F.
Lancet Oncol. Published Online 22 August 2016; http://dx.doi.org/10.1016/S1470-2045(16)30275-3

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Inauguration of IARC Regional Hub in Buenos Aires, Argentina
22/08/2016 -
In collaboration with the Ministry of Health of Argentina, the International Agency for Research on Cancer (IARC) inaugurated the Instituto Nacional del Cáncer in Buenos Aires, Argentina, as an IARC Regional Hub Coordinating Centre on 19 August 2016, as part of the Global Initiative for Cancer Registry Development (GICR).

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Overdiagnosis is a major driver of the thyroid cancer epidemic: up to 50–90% of thyroid cancers in women in high-income countries estimated to be overdiagnoses
18/08/2016 -
A new report by the International Agency for Research on Cancer (IARC) in collaboration with the Aviano National Cancer Institute in Italy, published today in The New England Journal of Medicine, shows that the growing epidemic of thyroid cancer reported in recent decades in several high-income countries is largely due to overdiagnosis.

Worldwide thyroid cancer epidemic? The increasing impact of overdiagnosis.
Vaccarella S, Franceschi S, Bray F, Wild CP, Plummer M, Dal Maso L.
N Engl J Med. Published Online 18 August 2016; http://dx.doi.org/10.1056/NEJMp1604412

Read article , Read IARC Press Release 246
Duration of adulthood overweight, obesity, and cancer risk in the Women’s Health Initiative
17/08/2016 -
In most high-income countries, obesity has become the leading risk factor for disease burden, including cancer. A new study led by researchers from the International Agency for Research on Cancer (IARC), published in PLoS Medicine, assesses the impact of duration of overweight and obesity during adulthood on cancer risk in a large cohort of women in the USA.

Duration of adulthood overweight, obesity, and cancer risk in the Women’s Health Initiative: a longitudinal study from the United States
Arnold M, Jiang L, Stefanick ML, Johnson KC, Lane DS, LeBlanc ES, et al.
PLoS Med. Published Online 16 August 2016; http://dx.doi.org/10.1371/journal.pmed.1002081

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IARC and the National Cancer Centre of the Republic of Belarus sign new partnership
08/08/2016 -
Joint research activities between the International Agency for Research on Cancer (IARC) and the Alexandrov National Cancer Centre of the Republic of Belarus (NCC) have been strengthened. A new Memorandum of Understanding signed by the IARC Director, Dr Christopher Wild, and the NCC Director, Dr Oleg Sukonko, will help assess the long-term health consequences of the Chernobyl accident, as well as improve the evaluation and implementation of cancer control strategies in the country.

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IARC Monographs Meetings - Volume 119: Some Chemicals in Food and Consumer Products
04/08/2016 -
IARC Monographs Volume 119: Some Chemicals in Food and Consumer Products
6-13 June 2017
Lyon, France

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IARC Monographs Volume 113: 2,4-Dichlorophenoxyacetic acid (2,4-D) and Some Organochlorine Insecticides
01/08/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the Monograph on 2,4-Dichlorophenoxyacetic acid (2,4-D) is now available online. The remaining Monographs of Volume 113 will be published subsequently.

Visit the Volume 113 webpage
IARC Monographs Volume 110: Perfluorooctanoic Acid, Tetrafluoroethylene, Dichloromethane, 1,2-Dichloropropane, and 1,3-Propane Sultone
20/07/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the Monograph on Perfluorooctanoic Acid (PFOA) is now available online. The remaining Monographs of Volume 110 will be published subsequently.

Visit the Volume 110 webpage
Photographs from IARC 50th anniversary conference
07/07/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that a gallery of photographs from the IARC 50th anniversary scientific conference, “Global Cancer: Occurrence, Causes, and Avenues to Prevention”, held in Lyon on 7–10 June 2016, is now available.

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Low selenium levels linked to liver cancer development
04/07/2016 -
A new study, published in The American Journal of Clinical Nutrition, shows that the highest levels of blood selenium or of selenoprotein P, the protein that distributes selenium from the liver around the body, are associated with a decreased risk of developing liver cancer (particularly hepatocellular carcinoma), even when all other major liver cancer risk factors are taken into account.

Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort
Hughes DJ, Duarte-Salles T, Hybsier S, Trichopoulou A, Stepien M, Aleksandrova K, et al.
Am J Clin Nutr. Published Online 29 June 2016; http://dx.doi.org/10.3945/ajcn.116.131672

Read article , IARC Press Release 245
Publication of IARC Handbooks of Cancer Prevention Volume 15: Breast Cancer Screening - in PDF format
01/07/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that Volume 15: Breast Cancer Screening of the IARC Handbooks of Cancer Prevention series is now available for purchase in PDF format. The volume contains the detailed assessments of a Working Group of 29 experts from 16 countries who met at IARC on 11–18 November 2014 to assess the cancer-preventive and adverse effects of different methods of screening for breast cancer. This book will also be available for purchase in print and EPUB formats later this year.

Read more
Video interviews from IARC 50th anniversary conference
30/06/2016 -
As part of its series of highlights from international oncology meetings, ecancer.tv features video interviews with participants at the International Agency for Research on Cancer (IARC) 50th anniversary conference, held in Lyon on 7–10 June 2016.

Watch videos
Circulating tumour DNA may play a crucial role in the detection of preclinical lung cancer
29/06/2016 -
A new study led by researchers from the International Agency for Research on Cancer (IARC) assessed the presence of TP53 mutations in the cell-free DNA (cfDNA) extracted from the plasma of 51 small-cell lung cancer cases and 225 non-cancer controls. The detection of TP53 mutations in 11% of the controls poses serious challenges for the use of cfDNA in early detection of cancer.

Identification of circulating tumor DNA for the early detection of small-cell lung cancer
Fernandez-Cuesta L, Perdomo S, Avogbe PH, Leblay N, Delhomme TM, Gaborieau V, et al.
EBioMedicine. 2016; http://dx.doi.org/10.1016/j.ebiom.2016.06.032

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IARC Monographs Volume 116: Evaluation of drinking coffee, maté, and very hot beverages
15/06/2016 -
The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, has evaluated the carcinogenicity of drinking coffee, maté, and very hot beverages. The detailed assessments will be published as Volume 116 of the IARC Monographs. A summary of the evaluations has now been published in The Lancet Oncology. Also available are a Q&A on the Volume 116 evaluations, a Fact sheet and Debunking the myths.

Loomis D, Guyton KZ, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, et al. Carcinogenicity of drinking coffee, maté, and very hot beverages The Lancet Oncology, Published online 15 June 2016; http://dx.doi.org/10.1016/S1470-2045(16)30239-X

Read article , Read IARC Press Release 244
Recordings of public lectures on 6 June 2016 now available
13/06/2016 -
Recordings of the public lectures held at IARC on Monday 6 June 2016 are now available. In parallel with the IARC 50th anniversary conference, IARC organized the event in association with the Institut National du Cancer (INCa), the Centre de Recherche en Cancérologie de Lyon (CRCL), the Centre Léon-Bérard, the Cancéropôle Lyon Auvergne Rhône-Alpes (CLARA), and the Hospices Civils de Lyon (HCL). The theme was “Making progress against cancer”. The speakers included Christopher P. Wild (Director, IARC), Alain Puisieux (Director, CRCL), Isabelle Romieu (Visiting Scientist, IARC), Thierry Breton (Director-General and interim President, INCa), and Véronique Trillet-Lenoir (President of the Executive Committee, CLARA).

Access recordings , Read programme
Making sense of carcinogens: a new method for navigating mechanistic data
08/06/2016 -
Today at the IARC 50th anniversary conference, Dr Martyn Smith is presenting the basis for a ground-breaking approach to identifying and organizing results from pertinent mechanistic studies in evaluations of carcinogenicity. This approach is based on the work of an international Working Group of experts convened by IARC, which identified 10 key characteristics that are commonly exhibited by established human carcinogens. Dr Smith is the lead author of the article, published in Environmental Health Perspectives.

Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, et al.
Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis
Environ Health Perspect 2016, 124(6):713–721; http://dx.doi.org/10.1289/ehp.1509912

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Global Cancer: Occurrence, Causes, and Avenues to Prevention - A conference to discuss today’s challenges and to help design tomorrow’s agenda
07/06/2016 -
On 7–10 June 2016, the International Agency for Research on Cancer (IARC) will bring together leading scientists in cancer research at the Centre de Congrès in Lyon, to discuss today’s challenges and design tomorrow’s agenda for cancer prevention research.

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WCRF Blog: 50 years of researching cancer
07/06/2016 -
An article by IARC Director Dr Christopher P. Wild is featured in the World Cancer Research Fund International blog. The article focuses on IARC’s 50 years of cancer research, including collaboration and achievements, and also looks at the future of cancer research.

Read the article
IARC 50th Anniversary Conference: Final programme and abstracts book now available
02/06/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the website for the conference Global Cancer: Occurrence, Causes, and Avenues to Prevention, to be held on 7–10 June 2016 at Centre de Congrès, Lyon, now contains the full detailed conference programme and links to all the conference abstracts. The programme book and abstracts book can also be downloaded from the website.

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IARC Monographs Meetings - Volume 116: Coffee, Mate, and Very Hot Beverages
20/05/2016 -
IARC Monographs Volume 116: Coffee, Mate, and Very Hot Beverages
24-31 May 2016
Lyon, France

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Launch of the Global Cancer Observatory (GCO) website
12/05/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce the launch of the Global Cancer Observatory (GCO), an interactive web-based platform providing global cancer statistics to inform cancer control and cancer research. The Cancer Today subsite of the GCO is a global data visualization tool that offers innovative ways to examine national estimates of the incidence, mortality, and prevalence of 27 cancer types in 184 countries, based on the GLOBOCAN database. The other subsites – Cancer over Time (which documents trends of cancer over time) and Cancer Tomorrow (which provides cancer predictions for the coming decades) – are in development. Each of these GCO subsites provides user-friendly and interactive tools for analysing and visualizing cancer data based on the most up-to-date statistics available, allowing users to visually explore the changing scale and profile of the global cancer burden.

The global cancer data included in the GCO come from several key projects of IARC's Section of Cancer Surveillance (CSU), including GLOBOCAN and Cancer Incidence in Five Continents. The GCO website will also link to related activities of CSU, including research that documents global cancer transitions and global efforts to support the collection of high-quality cancer registration data in low- and middle-income countries through the Global Initiative for Cancer Registry Development (GICR) partnership.

Visit the GCO website
IARC 50th Anniversary Conference: Updated programme now available
11/05/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the updated detailed programme is now available for the conference Global Cancer: Occurrence, Causes, and Avenues to Prevention, to be held on 7–10 June 2016 at Centre de Congrès, Lyon.

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IARC Publications: WHO Classification of Tumours of the Central Nervous System
11/05/2016 -
WHO Classification of Tumours of the Central Nervous System is the Revised 4th Edition of the WHO series on histological and genetic typing of human tumours. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors.

WHO Classification of Tumours of the Central Nervous System
WHO/IARC Classification of Tumours, 4th Edition Revised, Volume 1
Edited by Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Ellison DW, et al.

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Presentación del Código Europeo contra el Cáncer en España
28/04/2016 -
La Agencia Internacional para la Investigación en Cáncer (IARC, de sus siglas en ingles), agencia especializada en cáncer de la Organización Mundial de la Salud (OMS), presenta hoy la 4ª edición del Código Europeo contra el Cáncer en España con la participación de la Sociedad Española de Epidemiología.

Leer Comunicado de Prensa Nº 243
Chernobyl, 30 years on:
Interview of Dr A. Kesminiene on the research and health impact of the Chernobyl disaster

26/04/2016 -
26 April 2016 marks the 30th anniversary of the Chernobyl disaster – the worst nuclear accident of the last century. The accident led to a massive release of radioactive substances into the environment, including radioactive isotopes of iodine.
Dr Ausrele Kesminiene, Deputy Head of the Section of Environment and Radiation at the International Agency for Research on Cancer (IARC), has been studying the health effects of the Chernobyl disaster since 1991.

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Sharon Whelan (1948-2016)
13/04/2016 -
The International Agency for Research on Cancer (IARC) is deeply saddened by the passing of Sharon Whelan, an early staff of the Agency, who died on Tuesday 5 April 2016. Our deepest sympathy is with her son, Ben.

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World Indigenous Cancer Conference (12 - 14 April 2016)
12/04/2016 -
The International Agency for Research on Cancer (IARC) and the Menzies School of Health Research are launching the inaugural World Indigenous Cancer Conference. The 3-day event, which starts today in Brisbane, Australia, brings together researchers and public health practitioners as well as advocacy and indigenous community groups.

Watch video , Read IARC Press Release 237
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
08/04/2016 -
A new study conducted by the Pregnancy And Childhood Epigenetics (PACE) consortium, with collaboration from IARC's Epigenetics Group, on more than 6,000 mothers and their newborn children sampled from 13 cohorts worldwide, shows a profound deregulation of the epigenome in newborns of mothers who smoked during pregnancy. Epigenetic changes (DNA methylation) were identified in over 6,000 CpG sites, half of which span 2,017 genes (including the genes associated with cancer in adults) and represent new molecular changes that were not previously associated with smoking in either newborns or adults. Importantly, many of these epigenetic changes persist years later throughout childhood.

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, et al.
The American Journal of Human Genetics 98, 680–696, Published Online 7 April 2016; http://dx.doi.org/10.1016/j.ajhg.2016.02.019.

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IARC Monographs Meetings - Volume 118: Welding, Welding Fumes, and Some Related Chemicals
06/04/2016 -
IARC Monographs Volume 118: Welding, Welding Fumes, and Some Related Chemicals
21-28 March 2017
Lyon, France

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IARC Handbooks of Cancer Prevention Meetings - Volume 16
01/04/2016 -
IARC Handbooks of Cancer Prevention Volume 16
Weight Control
5-12 April 2016

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IARC Junior Investigator Awards 2016
04/03/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce the recipients of the IARC Junior Investigator Awards for 2016.

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IARC Monographs Volume 115: Evaluation of some industrial chemicals
24/02/2016 -
A Working Group of 24 experts from eight countries met at the International Agency for Research on Cancer (IARC) on 2-9 February 2016 to evaluate the carcinogenicity of seven industrial chemicals. A summary of the evaluations has now been published in The Lancet Oncology. The detailed assessments will be published as Volume 115 of the IARC Monographs.

Grosse Y, Loomis D, Guyton KZ, El Ghissassi F, Bouvard V, Benbrahim-Tallaa L, et al.
Carcinogenicity of some industrial chemicals
The Lancet Oncology, Published online 23 February 2016

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Inauguration of IARC Regional Hub in Izmir, Turkey
24/02/2016 -
In collaboration with the Ministry of Health of Turkey, the International Agency for Research on Cancer (IARC) is today inaugurating the Izmir Cancer Registry as an IARC Regional Hub for Cancer Registration, as part of the Global Initiative for Cancer Registry Development (GICR).

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Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study
18/02/2016 -
A new study, led by the International Agency for Research on Cancer (IARC), examined the potential of epigenetic (DNA methylation) changes in pre-diagnostic blood samples as a marker of exposure to tobacco smoke in a large multinational cohort (EPIC). The study comprehensively catalogued the smoking-associated alterations in the epigenome and showed that these alterations are reversible, underscoring the benefits of smoking cessation.

Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study
Ambatipudi A, Cuenin C, Hernandez-Vargas H, Ghantous A, Le Calvez-Kelm F, Kaaks R, et al.
Epigenomics, Published online 11 February 2016.

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New IARC report urges action against widespread mycotoxin contamination in developing countries
17/02/2016 -
A Working Group of world-leading experts convened by the International Agency for Research on Cancer (IARC), with support from the Bill & Melinda Gates Foundation, reviewed the health effects of aflatoxins and fumonisins. The panel concluded that these mycotoxins are not only a cause of acute poisoning and cancer but are also a likely contributor to the high levels of stunting in children in affected populations. The Working Group also identified effective measures to reduce exposure in developing countries. These recommendations have been published in the report "Mycotoxin control in low- and middle-income countries", which is available in English, French, and Spanish in print, PDF, and EPUB formats.

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Read IARC Press Release 242 , IARC Working Group Report No. 9
International Childhood Cancer Day: Much remains to be done to fight childhood cancer
15/02/2016 -
New estimates by the International Agency for Research on Cancer (IARC) show that the global occurrence of childhood cancer is higher than previously assessed. These estimates are based on data collected by more than 100 population-based cancer registries in 68 countries around the world in 2001–2010. International Childhood Cancer Day is observed on 15 February each year to raise worldwide public awareness about childhood cancer.

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IARC Meetings: Epigenetics and Environmental Origins of Cancer, 11–12 June 2016
05/02/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce a meeting on Epigenetics and Environmental Origins of Cancer, which will take place at IARC on 11–12 June 2016. The goals of this meeting are to evaluate recent scientific knowledge in the area, to determine future research needs, and to assess the implications of such studies in cancer causation and prevention. The meeting is a satellite event to the IARC 50th anniversary conference on Global Cancer: Occurrence, Causes, and Avenues to Prevention.

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World Cancer Day 2016: “We can. I can.”
04/02/2016 -
Each year on 4 February, WHO and the International Agency for Research on Cancer (IARC) support the Union for International Cancer Control (UICC) in promoting ways to reduce the global burden of cancer. The theme of the UICC campaign is "We can. I can." Five IARC experts explain how, together, we can prevent cancer.

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Senior Visiting Scientist Award 2015
03/02/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that the recipient of the 2015 highly competitive Senior Visiting Scientist Award is Professor Fanghui Zhao from the Department of Cancer Epidemiology, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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Podcast: Are We Fighting Cancer the Right Way?
02/02/2016 -
Podcast of Dr Christopher Wild serving as an expert witness on “Are We Fighting Cancer the Right Way?” in The Inquiry on the BBC World Service on 2 February 2016 (advance Seek Bar to 11:30)

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IARC Publications: WHO Classification of Tumours of the Urinary System and Male Genital Organs
27/01/2016 -
WHO Classification of Tumours of the Urinary System and Male Genital Organs is the eighth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly diseaseoriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors.

WHO Classification of Tumours of the Urinary System and Male Genital Organs
WHO/IARC Classification of Tumours, 4th Edition, Volume 8
Edited by H. Moch, P.A. Humphrey, T.M. Ulbright, V.E. Reuter

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Global patterns and trends in colorectal cancer incidence and mortality
27/01/2016 -
A study by scientists from the International Agency for Research on Cancer (IARC) shows that colorectal cancer incidence and mortality rates vary widely worldwide, with distinct gradients across human development levels, and trends point towards widening disparities and an increasing burden in countries in transition. The research was published online today in the journal Gut.

Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F
Global patterns and trends in colorectal cancer incidence and mortality
Gut, Published Online First 27 January 2016; http://dx.doi.org/10.1136/gutjnl-2015-310912

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Fellowships available for 4th Workshop on Emerging Issues in Oncogenic Virus Research
22/01/2016 -
Fellowships are available for the 4th Workshop on Emerging Issues in Oncogenic Virus Research, to be held in San Pietro in Bevagna, Manduria, Italy, on 15–19 June 2016. Applications are invited from junior scientists (PhD students and postdoctoral fellows) who are nationals of a Member State of the International Centre for Genetic Engineering and Biotechnology (ICGEB), which is supporting the fellowship programme.
Deadline: 15 March 2016

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IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism/Biomarkers Group
20/01/2016 -
A postdoctoral opportunity is immediately available within the Biomarkers Group to analyse high-resolution metabolomic data in large-scale epidemiological studies and interpret complex mass spectra to identify unknown metabolites.
Deadline: 15 February 2016

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Registration and abstract submission now open for the 4th Workshop on Emerging Issues in Oncogenic Virus Research
18/01/2016 -
The International Agency for Research on Cancer (IARC) is pleased to announce that registration and abstract submission are now open for the 4th Workshop on Emerging Issues in Oncogenic Virus Research. This workshop, to be held in San Pietro in Bevagna, Manduria, Italy, on 15–19 June 2016, will focus on novel oncogenic viruses and will also include new insights on well-established oncogenic viruses.

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European Code Against Cancer: scientific justification
12/01/2016 -
The journal Cancer Epidemiology has published a special issue on the 4th edition of the European Code Against Cancer, a project coordinated by the International Agency for Research on Cancer (IARC) with financial support from the European Commission. The special issue contains 14 scientific articles written by the working groups of experts who formulated the recommendations in the Code, explaining the rationale for the recommendations and the relevant scientific evidence.

European Code Against Cancer 4th Edition: 12 ways to reduce your cancer risk Cancer Epidemiology Volume 39, Supplement 1, Pages S1–S152 (December 2015)

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Precision in the Fight Against the Global Cancer Problem
08/01/2016 -
In an interview with the journal HealthManagement.org, Dr Christopher Wild, Director of the International Agency for Research on Cancer (IARC), stresses the importance of precision medicine in the fight against cancer and makes the argument for greater emphasis on cancer prevention to address the growing cancer burden worldwide.

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World Cancer Leader's Summit: Using tumour genomics in cancer prevention
04/01/2016 -
Dr Brennan talks to ecancertv at the World Cancer Leaders Summit in Istanbul, Turkey (17 - 18 November 2015), about his work with ZIARK in primary prevention and identifying new causes of cancer and secondary prevention through early detection.

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