|INDOOR EMISSIONS FROM HOUSEHOLD COAL COMBUSTION CARCINOGENIC: WOMEN IN LOW- OR MEDIUM-RESOURCE COUNTRIES MOST EXPOSED|
APPENDIX: ABOUT THE IARC MONOGRAPHS
What are the IARC Monographs?
The IARC Monographs identify environmental factors that can increase the risk of human cancer. These include chemicals, complex mixtures, occupational exposures, physical and biological agents, and lifestyle factors. National health agencies use this information as scientific support for their actions to prevent exposure to potential carcinogens.
The exposure circumstance entails exposures that are carcinogenic to humans.
This category includes agents, mixtures and exposure circumstances for which, at one extreme, the degree of evidence of carcinogenicity in humans is almost sufficient, as well as those for which, at the other extreme, there are no human data but for which there is evidence of carcinogenicity in experimental animals. Agents, mixtures and exposure circumstances are assigned to either group 2A (probably carcinogenic to humans) or group 2B (possibly carcinogenic to humans) on the basis of epidemiological and experimental evidence of carcinogenicity and other relevant data.
The exposure circumstance entails exposures that are probably carcinogenic to humans.
The exposure circumstance entails exposures that are possibly carcinogenic to humans.
This category is used most commonly for agents, mixtures and exposure circumstances for which the evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals. Exceptionally, agents (mixtures) for which the evidence of carcinogenicity is inadequate in humans but sufficient in experimental animals may be placed in this category when there is strong evidence that the mechanism of carcinogenicity in experimental animals does not operate in humans.
This category is used for agents or mixtures for which there is evidence suggesting lack of carcinogenicity in humans and in experimental animals. In some instances, agents or mixtures for which there is inadequate evidence of carcinogenicity in humans but evidence suggesting lack of carcinogenicity in experimental animals, consistently and strongly supported by a broad range of other relevant data, may be classified in this group.
FOR FURTHER INFORMATION
Contact Dr Nicolas Gaudin, Head of IARC Communications Group.
World Health Organization
International Agency for Research on Cancer
Organisation mondiale de la Santé
Centre international de Recherche sur le Cancer
150, cours Albert-Thomas 69372 Lyon Cedex 08 (France)
Telephone: 33 472 738 485 Facsimile: 33 472 738 311 http://www.iarc.fr