Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Recent Publications - 12 most recent publications

1. Joehanes R., Just A. C., Marioni R. E., Pilling L. C., Reynolds L. M., Mandaviya P. R., Guan W., Xu T., Elks C. E., Aslibekyan S., Moreno-Macias H., Smith J. A., Brody J. A., Dhingra R., Yousefi P., Pankow J. S., Kunze S., Shah S. H., McRae A. F., Lohman K., Sha J., Absher D. M., Ferrucci L., Zhao W., Demerath E. W., Bressler J., Grove M. L., Huan T., Liu C., Mendelson M. M., Yao C., Kiel D. P., Peters A., Wang-Sattler R., Visscher P. M., Wray N. R., Starr J. M., Ding J., Rodriguez C. J., Wareham N. J., Irvin M. R., Zhi D., Barrdahl M., Vineis P., Ambatipudi S., Uitterlinden A. G., Hofman A., Schwartz J., Colicino E., Hou L., Vokonas P. S., Hernandez D. G., Singleton A. B., Bandinelli S., Turner S. T., Ware E. B., Smith A. K., Klengel T., Binder E. B., Psaty B. M., Taylor K. D., Gharib S. A., Swenson B. R., Liang L., DeMeo D. L., O'Connor G. T., Herceg Z., Ressler K. J., Conneely K. N., Sotoodehnia N., Kardia S. L., Melzer D., Baccarelli A. A., van Meurs J. B., Romieu I., Arnett D. K., Ong K. K., Liu Y., Waldenberger M., Deary I. J., Fornage M., Levy D., London S. J. (2016) Epigenetic Signatures of Cigarette Smoking Circ Cardiovasc Genet; 9(5):436-447. PMID: 27651444

2. Ambatipudi S., Cuenin C., Hernandez-Vargas H., Ghantous A., Le Calvez-Kelm F., Kaaks R., Barrdahl M., Boeing H., Aleksandrova K., Trichopoulou A., Lagiou P., Naska A., Palli D., Krogh V., Polidoro S., Tumino R., Panico S., Bueno-de-Mesquita B., Peeters P. H., Quiros J. R., Navarro C., Ardanaz E., Dorronsoro M., Key T., Vineis P., Murphy N., Riboli E., Romieu I., Herceg Z. (2016) Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study Epigenomics; 8(5):599-618. PMID: 26864933

3. Esposti D. D., Hernandez-Vargas H., Voegele C., Fernandez-Jimenez N., Forey N., Bancel B., Le Calvez-Kelm F., McKay J., Merle P., Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing Oncotarget; 7(22):31862-77. PMID: 26887054

4. Joubert B. R., Felix J. F., Yousefi P., Bakulski K. M., Just A. C., Breton C., Reese S. E., Markunas C. A., Richmond R. C., Xu C. J., Kupers L. K., Oh S. S., Hoyo C., Gruzieva O., Soderhall C., Salas L. A., Baiz N., Zhang H., Lepeule J., Ruiz C., Ligthart S., Wang T., Taylor J. A., Duijts L., Sharp G. C., Jankipersadsing S. A., Nilsen R. M., Vaez A., Fallin M. D., Hu D., Litonjua A. A., Fuemmeler B. F., Huen K., Kere J., Kull I., Munthe-Kaas M. C., Gehring U., Bustamante M., Saurel-Coubizolles M. J., Quraishi B. M., Ren J., Tost J., Gonzalez J. R., Peters M. J., Haberg S. E., Xu Z., van Meurs J. B., Gaunt T. R., Kerkhof M., Corpeleijn E., Feinberg A. P., Eng C., Baccarelli A. A., Benjamin Neelon S. E., Bradman A., Merid S. K., Bergstrom A., Herceg Z., Hernandez-Vargas H., Brunekreef B., Pinart M., Heude B., Ewart S., Yao J., Lemonnier N., Franco O. H., Wu M. C., Hofman A., McArdle W., Van der Vlies P., Falahi F., Gillman M. W., Barcellos L. F., Kumar A., Wickman M., Guerra S., Charles M. A., Holloway J., Auffray C., Tiemeier H. W., Smith G. D., Postma D., Hivert M. F., Eskenazi B., Vrijheid M., Arshad H., Anto J. M., Dehghan A., Karmaus W., Annesi-Maesano I., Sunyer J., Ghantous A., Pershagen G., Holland N., Murphy S. K., DeMeo D. L., Burchard E. G., Ladd-Acosta C., Snieder H., Nystad W., Koppelman G. H., Relton C. L., Jaddoe V. W., Wilcox A., Melen E., London S. J. (2016) DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis Am J Hum Genet; 98(4):680-96. PMID: 27040690

5. van der Mei I., Lucas R. M., Taylor B. V., Valery P. C., Dwyer T., Kilpatrick T. J., Pender M. P., Williams D., Chapman C., Otahal P., Ponsonby A. L. (2016) Population attributable fractions and joint effects of key risk factors for multiple sclerosis Mult Scler; 22(4):461-9. PMID: 26199349

6. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

7. Grandin M., Mathot P., Devailly G., Bidet Y., Ghantous A., Favrot C., Gibert B., Gadot N., Puisieux I., Herceg Z., Delcros J. G., Bernet A., Mehlen P., Dante R. (2016) Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference EMBO Mol Med; 8(8):863-77. PMID: 27378792

8. Herceg Z. (2016) Epigenetic Mechanisms as an Interface Between the Environment and Genome Adv Exp Med Biol; 3-15. PMID: 27343085

9. Vuong T., Mallet J. F., Ouzounova M., Rahbar S., Hernandez-Vargas H., Herceg Z., Matar C. (2016) Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation J Transl Med; 13. PMID: 26762586

10. Accardi R., Gruffat H., Sirand C., Fusil F., Gheit T., Hernandez-Vargas H., Le Calvez-Kelm F., Traverse-Glehen A., Cosset F. L., Manet E., Wild C. P., Tommasino M. (2015) The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models Carcinogenesis; 36(11):1440-51. PMID: 26424750

11. Ancey P. B., Testoni B., Gruffaz M., Cros M. P., Durand G., Le Calvez-Kelm F., Durantel D., Herceg Z., Hernandez-Vargas H. (2015) Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes Oncotarget; . PMID: 26565721

12. Ghantous A., Hernandez-Vargas H., Byrnes G., Dwyer T., Herceg Z. (2015) Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk Mutagenesis; 30(6):733-42. PMID: 25724893