Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Recent Publications - 12 most recent publications

1. Ghantous A., Hernandez-Vargas H., Herceg Z. (2018) DNA Methylation Analysis from Blood Spots: Increasing Yield and Quality for Genome-Wide and Locus-Specific Methylation Analysis Methods Mol Biol; 605-619. PMID: 29224166

2. Bisarro Dos Reis M., Barros-Filho M. C., Marchi F. A., Beltrami C. M., Kuasne H., Pinto C. A. L., Ambatipudi S., Herceg Z., Kowalski L. P., Rogatto S. R. (2017) Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors J Clin Endocrinol Metab; 102(11):4089-4099. PMID: 28938489

3. Degli Esposti D., Aushev V. N., Lee E., Cros M. P., Zhu J., Herceg Z., Chen J., Hernandez-Vargas H. (2017) miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival Sci Rep; 7(1):15966. PMID: 29162888

4. Kettunen E., Hernandez-Vargas H., Cros M. P., Durand G., Le Calvez-Kelm F., Stuopelyte K., Jarmalaite S., Salmenkivi K., Anttila S., Wolff H., Herceg Z., Husgafvel-Pursiainen K. (2017) Asbestos-associated genome-wide DNA methylation changes in lung cancer Int J Cancer; 141(10):2014-2029. PMID: 28722770

5. Huskova H., Ardin M., Weninger A., Vargova K., Barrin S., Villar S., Olivier M., Stopka T., Herceg Z., Hollstein M., Zavadil J., Korenjak M. (2017) Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing Oncogene; 36(43):6041-6048. PMID: 28692054

6. Mathot P., Grandin M., Devailly G., Souaze F., Cahais V., Moran S., Campone M., Herceg Z., Esteller M., Juin P., Mehlen P., Dante R. (2017) DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment Oncogenesis; 6(10):e390. PMID: 29058695

7. Sharp G. C., Salas L. A., Monnereau C., Allard C., Yousefi P., Everson T. M., Bohlin J., Xu Z., Huang R. C., Reese S. E., Xu C. J., Baiz N., Hoyo C., Agha G., Roy R., Holloway J. W., Ghantous A., Merid S. K., Bakulski K. M., Kupers L. K., Zhang H., Richmond R. C., Page C. M., Duijts L., Lie R. T., Melton P. E., Vonk J. M., Nohr E. A., Williams-DeVane C., Huen K., Rifas-Shiman S. L., Ruiz-Arenas C., Gonseth S., Rezwan F. I., Herceg Z., Ekstrom S., Croen L., Falahi F., Perron P., Karagas M. R., Quraishi B. M., Suderman M., Magnus M. C., Jaddoe V. W. V., Taylor J. A., Anderson D., Zhao S., Smit H. A., Josey M. J., Bradman A., Baccarelli A. A., Bustamante M., Haberg S. E., Pershagen G., Hertz-Picciotto I., Newschaffer C., Corpeleijn E., Bouchard L., Lawlor D. A., Maguire R. L., Barcellos L. F., Davey Smith G., Eskenazi B., Karmaus W., Marsit C. J., Hivert M. F., Snieder H., Fallin M. D., Melen E., Munthe-Kaas M. C., Arshad H., Wiemels J. L., Annesi-Maesano I., Vrijheid M., Oken E., Holland N., Murphy S. K., Sorensen T. I. A., Koppelman G. H., Newnham J. P., Wilcox A. J., Nystad W., London S. J., Felix J. F., Relton C. L. (2017) Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium Hum Mol Genet; 26(20):4067-4085. PMID: 29016858

8. Narvaez D. M., Groot H., Diaz S. M., Palma R. M., Munoz N., Cros M. P., Hernandez-Vargas H. (2017) Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury Heliyon; 3(9):e00400. PMID: 28948237

9. Ancey P. B., Ecsedi S., Lambert M. P., Talukdar F. R., Cros M. P., Glaise D., Narvaez D. M., Chauvet V., Herceg Z., Corlu A., Hernandez-Vargas H. (2017) TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors Stem Cell Reports; 9(1):264-278. PMID: 28648900

10. Col E., Hoghoughi N., Dufour S., Penin J., Koskas S., Faure V., Ouzounova M., Hernandez-Vargash H., Reynoird N., Daujat S., Folco E., Vigneron M., Schneider R., Verdel A., Khochbin S., Herceg Z., Caron C., Vourc\'h C. (2017) Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock Sci Rep; 7(1):5418. PMID: 28710461

11. Hernandez-Vargas H., Gruffat H., Cros M. P., Diederichs A., Sirand C., Vargas-Ayala R. C., Jay A., Durand G., Le Calvez-Kelm F., Herceg Z., Manet E., Wild C. P., Tommasino M., Accardi R. (2017) Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines Sci Rep; 7(1):5852. PMID: 28724958

12. Ambatipudi S., Horvath S., Perrier F., Cuenin C., Hernandez-Vargas H., Le Calvez-Kelm F., Durand G., Byrnes G., Ferrari P., Bouaoun L., Sklias A., Chajes V., Overvad K., Severi G., Baglietto L., Clavel-Chapelon F., Kaaks R., Barrdahl M., Boeing H., Trichopoulou A., Lagiou P., Naska A., Masala G., Agnoli C., Polidoro S., Tumino R., Panico S., Dolle M., Peeters P. H., Onland-Moret N. C., Sandanger T. M., Nost T. H., Weiderpass E., Quiros J. R., Agudo A., Rodriguez-Barranco M., Huerta Castano J. M., Barricarte A., Fernandez A. M., Travis R. C., Vineis P., Muller D. C., Riboli E., Gunter M., Romieu I., Herceg Z. (2017) DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility Eur J Cancer; 299-307. PMID: 28259012