Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Previous Publications - All publications 2017-2013

1. Joehanes R., Just A. C., Marioni R. E., Pilling L. C., Reynolds L. M., Mandaviya P. R., Guan W., Xu T., Elks C. E., Aslibekyan S., Moreno-Macias H., Smith J. A., Brody J. A., Dhingra R., Yousefi P., Pankow J. S., Kunze S., Shah S. H., McRae A. F., Lohman K., Sha J., Absher D. M., Ferrucci L., Zhao W., Demerath E. W., Bressler J., Grove M. L., Huan T., Liu C., Mendelson M. M., Yao C., Kiel D. P., Peters A., Wang-Sattler R., Visscher P. M., Wray N. R., Starr J. M., Ding J., Rodriguez C. J., Wareham N. J., Irvin M. R., Zhi D., Barrdahl M., Vineis P., Ambatipudi S., Uitterlinden A. G., Hofman A., Schwartz J., Colicino E., Hou L., Vokonas P. S., Hernandez D. G., Singleton A. B., Bandinelli S., Turner S. T., Ware E. B., Smith A. K., Klengel T., Binder E. B., Psaty B. M., Taylor K. D., Gharib S. A., Swenson B. R., Liang L., DeMeo D. L., O'Connor G. T., Herceg Z., Ressler K. J., Conneely K. N., Sotoodehnia N., Kardia S. L., Melzer D., Baccarelli A. A., van Meurs J. B., Romieu I., Arnett D. K., Ong K. K., Liu Y., Waldenberger M., Deary I. J., Fornage M., Levy D., London S. J. (2016) Epigenetic Signatures of Cigarette Smoking Circ Cardiovasc Genet; 9(5):436-447. PMID: 27651444

2. Ambatipudi S., Cuenin C., Hernandez-Vargas H., Ghantous A., Le Calvez-Kelm F., Kaaks R., Barrdahl M., Boeing H., Aleksandrova K., Trichopoulou A., Lagiou P., Naska A., Palli D., Krogh V., Polidoro S., Tumino R., Panico S., Bueno-de-Mesquita B., Peeters P. H., Quiros J. R., Navarro C., Ardanaz E., Dorronsoro M., Key T., Vineis P., Murphy N., Riboli E., Romieu I., Herceg Z. (2016) Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study Epigenomics; 8(5):599-618. PMID: 26864933

3. Esposti D. D., Hernandez-Vargas H., Voegele C., Fernandez-Jimenez N., Forey N., Bancel B., Le Calvez-Kelm F., McKay J., Merle P., Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing Oncotarget; 7(22):31862-77. PMID: 26887054

4. Joubert B. R., Felix J. F., Yousefi P., Bakulski K. M., Just A. C., Breton C., Reese S. E., Markunas C. A., Richmond R. C., Xu C. J., Kupers L. K., Oh S. S., Hoyo C., Gruzieva O., Soderhall C., Salas L. A., Baiz N., Zhang H., Lepeule J., Ruiz C., Ligthart S., Wang T., Taylor J. A., Duijts L., Sharp G. C., Jankipersadsing S. A., Nilsen R. M., Vaez A., Fallin M. D., Hu D., Litonjua A. A., Fuemmeler B. F., Huen K., Kere J., Kull I., Munthe-Kaas M. C., Gehring U., Bustamante M., Saurel-Coubizolles M. J., Quraishi B. M., Ren J., Tost J., Gonzalez J. R., Peters M. J., Haberg S. E., Xu Z., van Meurs J. B., Gaunt T. R., Kerkhof M., Corpeleijn E., Feinberg A. P., Eng C., Baccarelli A. A., Benjamin Neelon S. E., Bradman A., Merid S. K., Bergstrom A., Herceg Z., Hernandez-Vargas H., Brunekreef B., Pinart M., Heude B., Ewart S., Yao J., Lemonnier N., Franco O. H., Wu M. C., Hofman A., McArdle W., Van der Vlies P., Falahi F., Gillman M. W., Barcellos L. F., Kumar A., Wickman M., Guerra S., Charles M. A., Holloway J., Auffray C., Tiemeier H. W., Smith G. D., Postma D., Hivert M. F., Eskenazi B., Vrijheid M., Arshad H., Anto J. M., Dehghan A., Karmaus W., Annesi-Maesano I., Sunyer J., Ghantous A., Pershagen G., Holland N., Murphy S. K., DeMeo D. L., Burchard E. G., Ladd-Acosta C., Snieder H., Nystad W., Koppelman G. H., Relton C. L., Jaddoe V. W., Wilcox A., Melen E., London S. J. (2016) DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis Am J Hum Genet; 98(4):680-96. PMID: 27040690

5. van der Mei I., Lucas R. M., Taylor B. V., Valery P. C., Dwyer T., Kilpatrick T. J., Pender M. P., Williams D., Chapman C., Otahal P., Ponsonby A. L. (2016) Population attributable fractions and joint effects of key risk factors for multiple sclerosis Mult Scler; 22(4):461-9. PMID: 26199349

6. Showeil R., Romano C., Valganon M., Lambros M., Trivedi P., Van Noorden S., Sriraksa R., El-Kaffash D., El-Etreby N., Natrajan R., Foroni L., Osborne R., El-Bahrawy M. (2016) The status of epidermal growth factor receptor in borderline ovarian tumours Oncotarget; 7(9):10568-77. PMID: 26870997

7. Vuong T., Mallet J. F., Ouzounova M., Rahbar S., Hernandez-Vargas H., Herceg Z., Matar C. (2016) Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation J Transl Med; 13. PMID: 26762586

8. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

9. Herceg Z. (2016) Epigenetic Mechanisms as an Interface Between the Environment and Genome Adv Exp Med Biol; 3-15. PMID: 27343085

10. Grandin M., Mathot P., Devailly G., Bidet Y., Ghantous A., Favrot C., Gibert B., Gadot N., Puisieux I., Herceg Z., Delcros J. G., Bernet A., Mehlen P., Dante R. (2016) Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference EMBO Mol Med; 8(8):863-77. PMID: 27378792

11. Accardi R., Gruffat H., Sirand C., Fusil F., Gheit T., Hernandez-Vargas H., Le Calvez-Kelm F., Traverse-Glehen A., Cosset F. L., Manet E., Wild C. P., Tommasino M. (2015) The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models Carcinogenesis; 36(11):1440-51. PMID: 26424750

12. Ancey P. B., Testoni B., Gruffaz M., Cros M. P., Durand G., Le Calvez-Kelm F., Durantel D., Herceg Z., Hernandez-Vargas H. (2015) Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes Oncotarget; . PMID: 26565721

13. Ghantous A., Hernandez-Vargas H., Byrnes G., Dwyer T., Herceg Z. (2015) Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk Mutagenesis; 30(6):733-42. PMID: 25724893

14. Stronach E. A., Cunnea P., Turner C., Guney T., Aiyappa R., Jeyapalan S., de Sousa C. H., Browne A., Magdy N., Studd J. B., Sriraksa R., Gabra H., El-Bahrawy M. (2015) The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma Oncotarget; 6(31):31593-603. PMID: 26267317

15. Torabi K., Miro R., Fernandez-Jimenez N., Quintanilla I., Ramos L., Prat E., Del Rey J., Pujol N., Killian J. K., Meltzer P. S., Fernandez P. L., Ried T., Lozano J. J., Camps J., Ponsa I. (2015) Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer Carcinogenesis; 36(10):1103-10. PMID: 26243311

16. Hernandez-Vargas H., Castelino J., Silver M. J., Dominguez-Salas P., Cros M. P., Durand G., Calvez-Kelm F. L., Prentice A. M., Wild C. P., Moore S. E., Hennig B. J., Herceg Z., Gong Y. Y., Routledge M. N. (2015) Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia Int J Epidemiol; 44(4):1238-48. PMID: 25855716

17. Taylor N. J., Reiner A. S., Begg C. B., Cust A. E., Busam K. J., Anton-Culver H., Dwyer T., From L., Gallagher R. P., Gruber S. B., Rosso S., White K. A., Zanetti R., Orlow I., Thomas N. E., Rebbeck T. R., Berwick M., Kanetsky P. A., G. E. M. Study Grp (2015) Inherited variation at MC1R and ASIP and association with melanoma-specific survival Int. J Cancer; 136(11):2659-2667. PMID: WOS:000351357700017

18. Taylor N. J., Busam K. J., From L., Groben P. A., Anton-Culver H., Cust A. E., Begg C. B., Dwyer T., Gallagher R. P., Gruber S. B., Orlow I., Rosso S., Thomas N. E., Zanetti R., Rebbeck T. R., Berwick M., Kanetsky P. A. (2015) Inherited Variation at MC1R and Histological Characteristics of Primary Melanoma PLoS ONE; 10(3):10. PMID: 25790105

19. da Costa A.N., Plymoth A., Santos-Silva D., Ortiz-Cuaran S., Camey S., Guilloreau P., Sangrajrang S., Khuhaprema T., Mendy M., Lesi O.A., Chang H.K., Oh J.K., Lee D.H., Shin H.R., Kirk G.D., Merle P., Beretta L., Hainaut P. (2015) Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma Int J Cancer; 136(1):172-181. PMID: 24803312

20. Wild C.P., Bucher J.R., de Jong B.W., Dillner J., von Gertten C., Groopman J.D., Herceg Z., Holmes E., Holmila R., Olsen J.H., Ringborg U., Scalbert A., Shibata T., Smith M.T., Ulrich C., Vineis P., McLaughlin J. (2015) Translational Cancer Research: Balancing Prevention and Treatment to Combat Cancer Globally J Natl Cancer Inst; 107(1):353. PMID: 25515230

21. Lambert M.P., Ancey P.B., Esposti D.D., Cros M.P., Sklias A., Scoazec J.Y., Durantel D., Hernandez-Vargas H., Herceg Z. (2015) Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors Clin. Epigenetics; 7(1):15. PMID: 25755686

22. Kuasne H., Colus I.M., Busso A.F., Hernandez-Vargas H., Barros-Filho M.C., Marchi F.A., Scapulatempo-Neto C., Faria E.F., Lopes A., Guimaraes G.C., Herceg Z., Rogatto S.R. (2015) Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers Clin. Epigenetics; 7(1):46. PMID: 25908946

23. Silver M.J., Kessler N.J., Hennig B.J., Dominguez-Salas P., Laritsky E., Baker M.S., Coarfa C., Hernandez-Vargas H., Castelino J.M., Routledge M.N., Gong Y.Y., Herceg Z., Lee Y.S., Lee K., Moore S.E., Fulford A.J., Prentice A.M., Waterland R.A. (2015) Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment Genome Biol; 16(1):118. PMID: 26062908

24. Vaca-Paniagua F., Oliver J., Nogueira da Costa A., Merle P., McKay J., Herceg Z., Holmila R. (2015) Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing Epigenomics; 7(3):353-362. PMID: 26077425

25. Kracker S., Di Virgilio M., Schwartzentruber J., Cuenin C., Forveille M., Deau M.C., McBride K.M., Majewski J., Gazumyan A., Seneviratne S., Grimbacher B., Kutukculer N., Herceg Z., Cavazzana M., Jabado N., Nussenzweig M.C., Fischer A., Durandy A. (2015) An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex J Allergy Clin. Immunol; 135(4):998-1007. PMID: 25312759

26. Paltiel O., Tikellis G., Linet M., Golding J., Lemeshow S., Phillips G., Lamb K., Stoltenberg C., Haberg S.E., Strom M., Granstrom C., Northstone K., Klebanoff M., Ponsonby A.L., Milne E., Pedersen M., Kogevinas M., Ha E., Dwyer T. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C) Paediatr. Perinat. Epidemiol; 29(4):335-345. PMID: 25989709

27. Sahay D., Leblanc R., Grunewald T.G., Ambatipudi S., Ribeiro J., Clezardin P., Peyruchaud O. (2015) The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer Oncotarget; 6(24):20604-20620. PMID: 26098771

28. Lee H. S. (2015) Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood Nutrients; 7(11):9492-507. PMID: 26593940

29. Ichim G., Mola M., Finkbeiner M.G., Cros M.P., Herceg Z., Hernandez-Vargas H. (2014) The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene; 33(2):181-192.

30. Lee H.S., Herceg Z. (2014) The epigenome and cancer prevention: A complex story of dietary supplementation Cancer Lett; 342(2):275-284.

31. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650.

32. Tapias A., Zhou Z.W., Shi Y., Chong Z., Wang P., Groth M., Platzer M., Huttner W., Herceg Z., Yang Y.G., Wang Z.Q. (2014) Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions Cell Stem Cell; 14(5):632-643.

33. Ponsonby A.L., Dwyer T. (2014) Statistics: Biomedicine must look beyond P values Nature; 507(7491):169.

34. Siouda M., Frecha C., Accardi R., Yue J., Cuenin C., Gruffat H., Manet E., Herceg Z., Sylla B.S., Tommasino M. (2014) Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression PLoS Pathog; 10(5):e1004125.

35. Ecsedi S., Hernandez-Vargas H., Lima S.C., Vizkeleti L., Toth R., Lazar V., Koroknai V., Kiss T., Emri G., Herceg Z., Adany R., Balazs M. (2014) DNA methylation characteristics of primary melanomas with distinct biological behaviour PLoS ONE; 9(5):e96612.

36. Herceg Z. (2014) Cancer prevention potential of diet and dietary supplements in epigenome modulation ; 43-70.

37. Ghantous A., Saffery R., Cros M.P., Ponsonby A.L., Hirschfeld S., Kasten C., Dwyer T., Herceg Z., Hernandez-Vargas H. (2014) Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling BMC. Biotechnol; 60.

38. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC. Genomics; 435.

39. Leduc C., Chemin G., Puget N., Sawan C., Moutahir M., Herceg Z., Khamlichi A.A. (2014) Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells Cell Cycle; 13(10):1583-1589.

40. Wang N., Tikellis G., Sun C., Pezic A., Wang L., Wells J.C., Cochrane J., Ponsonby A.L., Dwyer T. (2014) The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio Placenta; 35(7):437-441.

41. Guillot C., Favaudon V., Herceg Z., Sagne C., Sauvaigo S., Merle P., Hall J., Chemin I. (2014) PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models BMC. Cancer; 603.

42. Hedley C., Sriraksa R., Showeil R., Van Noorden S., El-Bahrawy M. (2014) The frequency and significance of WT-1 expression in serous endometrial carcinoma Hum Pathol; 45(9):1879-1884.

43. Guillot C., Hall J., Herceg Z., Merle P., Chemin I. (2014) Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy Clin Res Hepatol. Gastroenterol; 38(2):137-142.

44. McCloskey K., Sun C., Pezic A., Cochrane J., Morley R., Vuillermin P., Burgner D., Dwyer T., Ponsonby A.L. (2014) The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study J Dev. Orig. Health Dis; 5(4):307-313.

45. Berwick M., MacArthur J., Orlow I., Kanetsky P., Begg C.B., Luo L., Reiner A., Sharma A., Armstrong B.K., Kricker A., Cust A.E., Marrett L.D., Gruber S.B., Anton-Culver H., Zanetti R., Rosso S., Gallagher R.P., Dwyer T., Venn A., Busam K., From L., White K., Thomas N.E. (2014) MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors Pigment Cell Melanoma Res; 27(3):485-488.

46. Caygill C.P., Gatenby P.A., Herceg Z., Lima S.C., Pinto L.F., Watson A., Wu M.S. (2014) Comparative genomic analysis of esophageal cancers Ann N. Y. Acad Sci; 1325(1):69-76.

47. Durandy A, Kracker S., Schwartzentruber J., Cuenin C., Herceg Z., Jabado N., Nejentsev S, Fischer A. (2014) Immunoglobulin class-switch recombination deficiencies. Selected Abstracts from the 100th J Project Meeting, Antalya, Turkey, March 12-14, 2014 J Clin Immunol; 34(6):696.

48. Lee H.S., Barraza-Villarreal A., Biessy C., Duarte-Salles T., Sly P.D., Ramakrishnan U., Rivera J., Herceg Z., Romieu I. (2014) Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants Physiol Genomics; 46(23):851-857.

49. Thomas N.E., Kricker A., Waxweiler W.T., Dillon P.M., Busam K.J., From L., Groben P.A., Armstrong B.K., Anton-Culver H., Gruber S.B., Marrett L.D., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Orlow I., Paine S., Ollila D.W., Reiner A.S., Luo L., Hao H., Frank J.S., Begg C.B., Berwick M. (2014) Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas: A Population-Based Study JAMA Dermatol; 150(12):1306-1314.

50. Gospodinov A., Herceg Z. (2013) Shaping chromatin for repair Mutat Res; 752(1):45-60.

51. Genevois A.L., Ichim G., Coissieux M.M., Lambert M.P., Lavial F., Goldschneider D., Jarrosson-Wuilleme L., Lepinasse F., Gouysse G., Herceg Z., Scoazec J.Y., Tauszig-Delamasure S., Mehlen P. (2013) Dependence receptor TrkC is a putative colon cancer tumor suppressor Proc Natl Acad Sci U S A; 110(8):3017-3022.

52. Herceg Z., Lambert M.P., van Veldhoven K., Demetriou C., Vineis P., Smith M.T., Straif K., Wild C.P. (2013) Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation Carcinogenesis; 34(9):1955-1967.

53. Lee H.S., Barraza-Villarreal A., Hernandez-Vargas H., Sly P.D., Biessy C., Ramakrishnan U., Romieu I., Herceg Z. (2013) Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study Am. J Clin Nutr; 98(2):480-487.

54. Wild C.P., Scalbert A., Herceg Z. (2013) Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk Environ. Mol. Mutagen; 54(7):480-499.

55. Demetriou C.A., Chen J., Polidoro S., van Veldhoven K., Cuenin C., Campanella G., Brennan K., Clavel-Chapelon F., Dossus L., Kvaskoff M., Drogan D., Boeing H., Kaaks R., Risch A., Trichopoulos D., Lagiou P., Masala G., Sieri S., Tumino R., Panico S., Quiros J.R., Sanchez Perez M.J., Amiano P., Huerta Castano J.M., Ardanaz E., Onland-Moret C., Peeters P., Khaw K.T., Wareham N., Key T.J., Travis R.C., Romieu I., Gallo V., Gunter M., Herceg Z., Kyriacou K., Riboli E., Flanagan J.M., Vineis P. (2013) Methylome analysis and epigenetic changes associated with menarcheal age PLoS ONE; 8(11):e79391.

56. Lee H.S., Hernandez-Vargas H., Biessy C., Romieu I., Herceg Z., Barraza-Villarreal A., Sly P.D., Ramakrishnan U. (2013) Am. J Clin Nutr; 98(6):1595-1596.

57. Ecsedi S.I., Hernandez-Vargas H., Lima S.C., Herceg Z., Adany R., Balazs M. (2013) Transposable hypomethylation is associated with metastatic capacity of primary melanomas Int. J Clin Exp. Pathol; 6(12):2943-2948.

58. Aushev V.N., Zborovskaya I.B., Laktionov K.K., Girard N., Cros M.P., Herceg Z., Krutovskikh V. (2013) Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma PLoS ONE; 8(10):e78649.

59. Gospodinov A., Herceg Z. (2013) Chromatin structure in double strand break repair DNA Repair (Amst); 12(10):800-810.

60. Umer M., Herceg Z. (2013) Deciphering the epigenetic code: an overview of DNA methylation analysis methods Antioxid. Redox. Signal; 18(15):1972-1986.

61. Ouzounova M., Vuong T., Ancey P.B., Ferrand M., Durand G., Le-Calvez Kelm F., Croce C., Matar C., Herceg Z., Hernandez-Vargas H. (2013) MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells BMC. Genomics; 139.

62. Khoury M.J., Lam T.K., Ioannidis J.P., Hartge P., Spitz M.R., Buring J.E., Chanock S.J., Croyle R.T., Goddard K.A., Ginsburg G.S., Herceg Z., Hiatt R.A., Hoover R.N., Hunter D.J., Kramer B.S., Lauer M.S., Meyerhardt J.A., Olopade O.I., Palmer J.R., Sellers T.A., Seminara D., Ransohoff D.F., Rebbeck T.R., Tourassi G., Winn D.M., Zauber A., Schully S.D. (2013) Transforming epidemiology for 21st century medicine and public health Cancer Epidemiol Biomarkers Prev; 22(4):508-516.

63. Ghantous A., Sinjab A., Herceg Z., Darwiche N. (2013) Parthenolide: from plant shoots to cancer roots Drug Discov. Today; 18(17):894-905.

64. Aury-Landas J., Bougeard G., Castel H., Hernandez-Vargas H., Drouet A., Latouche J.B., Schouft M.T., Ferec C., Leroux D., Lasset C., Coupier I., Caron O., Herceg Z., Frebourg T., Flaman J.M. (2013) Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours Eur. J Hum Genet; 21(12):1369-1376.

65. Rakosy Z., Ecsedi S., Toth R., Vizkeleti L., Hernandez-Vargas H., Lazar V., Emri G., Szatmari I., Herceg Z., Adany R., Balazs M. (2013) Integrative genomics identifies gene signature associated with melanoma ulceration PLoS ONE; 8(1):e54958.

66. Sawan C., Hernandez-Vargas H., Murr R., Lopez F., Vaissiere T., Ghantous A.Y., Cuenin C., Imbert J., Wang Z.Q., Ren B., Herceg Z. (2013) Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells Stem Cells; 31(5):979-991.

67. Browne A., Sriraksa R., Guney T., Rama N., Van Noorden S., Curry E., Gabra H., Stronach E., El-Bahrawy M. (2013) Differential expression of IL-8 and IL-8 receptors in benign, borderline and malignant ovarian epithelial tumours Cytokine; 64(1):413-421.

68. Thomas N.E., Busam K.J., From L., Kricker A., Armstrong B.K., Anton-Culver H., Gruber S.B., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Groben P.A., Hao H., Orlow I., Reiner A.S., Luo L., Paine S., Ollila D.W., Wilcox H., Begg C.B., Berwick M. (2013) Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study J Clin Oncol; 31(33):4252-4259.

69. El Hajj H., Ali J., Ghantous A., Hodroj D., Daher A., Zibara K., Journo C., Otrock Z., Zaatari G., Mahieux R., El Sabban M., Bazarbachi A., Abou Merhi R. (2013) Combination of arsenic and interferon-alpha inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas PLoS ONE; 8(11):e79474.