Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Previous Publications - All publications 2017-2013

1. Ambatipudi S., Horvath S., Perrier F., Cuenin C., Hernandez-Vargas H., Le Calvez-Kelm F., Durand G., Byrnes G., Ferrari P., Bouaoun L., Sklias A., Chajes V., Overvad K., Severi G., Baglietto L., Clavel-Chapelon F., Kaaks R., Barrdahl M., Boeing H., Trichopoulou A., Lagiou P., Naska A., Masala G., Agnoli C., Polidoro S., Tumino R., Panico S., Dolle M., Peeters P. H., Onland-Moret N. C., Sandanger T. M., Nost T. H., Weiderpass E., Quiros J. R., Agudo A., Rodriguez-Barranco M., Huerta Castano J. M., Barricarte A., Fernandez A. M., Travis R. C., Vineis P., Muller D. C., Riboli E., Gunter M., Romieu I., Herceg Z. (2017) DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility Eur J Cancer; 299-307. PMID: 28259012

2. Vineis P., Chadeau-Hyam M., Gmuender H., Gulliver J., Herceg Z., Kleinjans J., Kogevinas M., Kyrtopoulos S., Nieuwenhuijsen M., Phillips D. H., Probst-Hensch N., Scalbert A., Vermeulen R., Wild C. P. (2017) The exposome in practice: Design of the EXPOsOMICS project Int J Hyg Environ Health; 220(2):142-151. PMID: 27576363

3. Beltrami C. M., Dos Reis M. B., Barros-Filho M. C., Marchi F. A., Kuasne H., Pinto C. A. L., Ambatipudi S., Herceg Z., Kowalski L. P., Rogatto S. R. (2017) Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas Clin Epigenetics; 45. PMID: 28469731

4. Holmila R., Sklias A., Muller D. C., Degli Esposti D., Guilloreau P., McKay J., Sangrajrang S., Srivatanakul P., Hainaut P., Merle P., Herceg Z., Nogueira da Costa A. (2017) Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma PLoS ONE; 12(3):e0174265. PMID: 28333958

5. Joehanes R., Just A. C., Marioni R. E., Pilling L. C., Reynolds L. M., Mandaviya P. R., Guan W., Xu T., Elks C. E., Aslibekyan S., Moreno-Macias H., Smith J. A., Brody J. A., Dhingra R., Yousefi P., Pankow J. S., Kunze S., Shah S. H., McRae A. F., Lohman K., Sha J., Absher D. M., Ferrucci L., Zhao W., Demerath E. W., Bressler J., Grove M. L., Huan T., Liu C., Mendelson M. M., Yao C., Kiel D. P., Peters A., Wang-Sattler R., Visscher P. M., Wray N. R., Starr J. M., Ding J., Rodriguez C. J., Wareham N. J., Irvin M. R., Zhi D., Barrdahl M., Vineis P., Ambatipudi S., Uitterlinden A. G., Hofman A., Schwartz J., Colicino E., Hou L., Vokonas P. S., Hernandez D. G., Singleton A. B., Bandinelli S., Turner S. T., Ware E. B., Smith A. K., Klengel T., Binder E. B., Psaty B. M., Taylor K. D., Gharib S. A., Swenson B. R., Liang L., DeMeo D. L., O'Connor G. T., Herceg Z., Ressler K. J., Conneely K. N., Sotoodehnia N., Kardia S. L., Melzer D., Baccarelli A. A., van Meurs J. B., Romieu I., Arnett D. K., Ong K. K., Liu Y., Waldenberger M., Deary I. J., Fornage M., Levy D., London S. J. (2016) Epigenetic Signatures of Cigarette Smoking Circ Cardiovasc Genet; 9(5):436-447. PMID: 27651444

6. Ambatipudi S., Cuenin C., Hernandez-Vargas H., Ghantous A., Le Calvez-Kelm F., Kaaks R., Barrdahl M., Boeing H., Aleksandrova K., Trichopoulou A., Lagiou P., Naska A., Palli D., Krogh V., Polidoro S., Tumino R., Panico S., Bueno-de-Mesquita B., Peeters P. H., Quiros J. R., Navarro C., Ardanaz E., Dorronsoro M., Key T., Vineis P., Murphy N., Riboli E., Romieu I., Herceg Z. (2016) Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study Epigenomics; 8(5):599-618. PMID: 26864933

7. Esposti D. D., Hernandez-Vargas H., Voegele C., Fernandez-Jimenez N., Forey N., Bancel B., Le Calvez-Kelm F., McKay J., Merle P., Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing Oncotarget; 7(22):31862-77. PMID: 26887054

8. Joubert B. R., Felix J. F., Yousefi P., Bakulski K. M., Just A. C., Breton C., Reese S. E., Markunas C. A., Richmond R. C., Xu C. J., Kupers L. K., Oh S. S., Hoyo C., Gruzieva O., Soderhall C., Salas L. A., Baiz N., Zhang H., Lepeule J., Ruiz C., Ligthart S., Wang T., Taylor J. A., Duijts L., Sharp G. C., Jankipersadsing S. A., Nilsen R. M., Vaez A., Fallin M. D., Hu D., Litonjua A. A., Fuemmeler B. F., Huen K., Kere J., Kull I., Munthe-Kaas M. C., Gehring U., Bustamante M., Saurel-Coubizolles M. J., Quraishi B. M., Ren J., Tost J., Gonzalez J. R., Peters M. J., Haberg S. E., Xu Z., van Meurs J. B., Gaunt T. R., Kerkhof M., Corpeleijn E., Feinberg A. P., Eng C., Baccarelli A. A., Benjamin Neelon S. E., Bradman A., Merid S. K., Bergstrom A., Herceg Z., Hernandez-Vargas H., Brunekreef B., Pinart M., Heude B., Ewart S., Yao J., Lemonnier N., Franco O. H., Wu M. C., Hofman A., McArdle W., Van der Vlies P., Falahi F., Gillman M. W., Barcellos L. F., Kumar A., Wickman M., Guerra S., Charles M. A., Holloway J., Auffray C., Tiemeier H. W., Smith G. D., Postma D., Hivert M. F., Eskenazi B., Vrijheid M., Arshad H., Anto J. M., Dehghan A., Karmaus W., Annesi-Maesano I., Sunyer J., Ghantous A., Pershagen G., Holland N., Murphy S. K., DeMeo D. L., Burchard E. G., Ladd-Acosta C., Snieder H., Nystad W., Koppelman G. H., Relton C. L., Jaddoe V. W., Wilcox A., Melen E., London S. J. (2016) DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis Am J Hum Genet; 98(4):680-96. PMID: 27040690

9. van der Mei I., Lucas R. M., Taylor B. V., Valery P. C., Dwyer T., Kilpatrick T. J., Pender M. P., Williams D., Chapman C., Otahal P., Ponsonby A. L. (2016) Population attributable fractions and joint effects of key risk factors for multiple sclerosis Mult Scler; 22(4):461-9. PMID: 26199349

10. Showeil R., Romano C., Valganon M., Lambros M., Trivedi P., Van Noorden S., Sriraksa R., El-Kaffash D., El-Etreby N., Natrajan R., Foroni L., Osborne R., El-Bahrawy M. (2016) The status of epidermal growth factor receptor in borderline ovarian tumours Oncotarget; 7(9):10568-77. PMID: 26870997

11. Herceg Z. (2016) Epigenetic Mechanisms as an Interface Between the Environment and Genome Adv Exp Med Biol; 3-15. PMID: 27343085

12. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

13. Grandin M., Mathot P., Devailly G., Bidet Y., Ghantous A., Favrot C., Gibert B., Gadot N., Puisieux I., Herceg Z., Delcros J. G., Bernet A., Mehlen P., Dante R. (2016) Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference EMBO Mol Med; 8(8):863-77. PMID: 27378792

14. Vuong T., Mallet J. F., Ouzounova M., Rahbar S., Hernandez-Vargas H., Herceg Z., Matar C. (2016) Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation J Transl Med; 14(13):1-12. PMID: 26762586

15. Accardi R., Gruffat H., Sirand C., Fusil F., Gheit T., Hernandez-Vargas H., Le Calvez-Kelm F., Traverse-Glehen A., Cosset F. L., Manet E., Wild C. P., Tommasino M. (2015) The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models Carcinogenesis; 36(11):1440-51. PMID: 26424750

16. Ghantous A., Hernandez-Vargas H., Byrnes G., Dwyer T., Herceg Z. (2015) Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk Mutagenesis; 30(6):733-42. PMID: 25724893

17. Ancey P. B., Testoni B., Gruffaz M., Cros M. P., Durand G., Le Calvez-Kelm F., Durantel D., Herceg Z., Hernandez-Vargas H. (2015) Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes Oncotarget; . PMID: 26565721

18. Torabi K., Miro R., Fernandez-Jimenez N., Quintanilla I., Ramos L., Prat E., Del Rey J., Pujol N., Killian J. K., Meltzer P. S., Fernandez P. L., Ried T., Lozano J. J., Camps J., Ponsa I. (2015) Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer Carcinogenesis; 36(10):1103-10. PMID: 26243311

19. Stronach E. A., Cunnea P., Turner C., Guney T., Aiyappa R., Jeyapalan S., de Sousa C. H., Browne A., Magdy N., Studd J. B., Sriraksa R., Gabra H., El-Bahrawy M. (2015) The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma Oncotarget; 6(31):31593-603. PMID: 26267317

20. Hernandez-Vargas H., Castelino J., Silver M. J., Dominguez-Salas P., Cros M. P., Durand G., Calvez-Kelm F. L., Prentice A. M., Wild C. P., Moore S. E., Hennig B. J., Herceg Z., Gong Y. Y., Routledge M. N. (2015) Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia Int J Epidemiol; 44(4):1238-48. PMID: 25855716

21. Taylor N. J., Reiner A. S., Begg C. B., Cust A. E., Busam K. J., Anton-Culver H., Dwyer T., From L., Gallagher R. P., Gruber S. B., Rosso S., White K. A., Zanetti R., Orlow I., Thomas N. E., Rebbeck T. R., Berwick M., Kanetsky P. A., G. E. M. Study Grp (2015) Inherited variation at MC1R and ASIP and association with melanoma-specific survival Int. J Cancer; 136(11):2659-2667. PMID: WOS:000351357700017

22. Taylor N. J., Busam K. J., From L., Groben P. A., Anton-Culver H., Cust A. E., Begg C. B., Dwyer T., Gallagher R. P., Gruber S. B., Orlow I., Rosso S., Thomas N. E., Zanetti R., Rebbeck T. R., Berwick M., Kanetsky P. A. (2015) Inherited Variation at MC1R and Histological Characteristics of Primary Melanoma PLoS ONE; 10(3):10. PMID: 25790105

23. Kuasne H., Colus I.M., Busso A.F., Hernandez-Vargas H., Barros-Filho M.C., Marchi F.A., Scapulatempo-Neto C., Faria E.F., Lopes A., Guimaraes G.C., Herceg Z., Rogatto S.R. (2015) Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers Clin. Epigenetics; 7(1):46. PMID: 25908946

24. Lambert M.P., Ancey P.B., Esposti D.D., Cros M.P., Sklias A., Scoazec J.Y., Durantel D., Hernandez-Vargas H., Herceg Z. (2015) Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors Clin. Epigenetics; 7(1):15. PMID: 25755686

25. Vaca-Paniagua F., Oliver J., Nogueira da Costa A., Merle P., McKay J., Herceg Z., Holmila R. (2015) Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing Epigenomics; 7(3):353-362. PMID: 26077425

26. Silver M.J., Kessler N.J., Hennig B.J., Dominguez-Salas P., Laritsky E., Baker M.S., Coarfa C., Hernandez-Vargas H., Castelino J.M., Routledge M.N., Gong Y.Y., Herceg Z., Lee Y.S., Lee K., Moore S.E., Fulford A.J., Prentice A.M., Waterland R.A. (2015) Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment Genome Biol; 16(1):118. PMID: 26062908

27. da Costa A.N., Plymoth A., Santos-Silva D., Ortiz-Cuaran S., Camey S., Guilloreau P., Sangrajrang S., Khuhaprema T., Mendy M., Lesi O.A., Chang H.K., Oh J.K., Lee D.H., Shin H.R., Kirk G.D., Merle P., Beretta L., Hainaut P. (2015) Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma Int J Cancer; 136(1):172-181. PMID: 24803312

28. Kracker S., Di Virgilio M., Schwartzentruber J., Cuenin C., Forveille M., Deau M.C., McBride K.M., Majewski J., Gazumyan A., Seneviratne S., Grimbacher B., Kutukculer N., Herceg Z., Cavazzana M., Jabado N., Nussenzweig M.C., Fischer A., Durandy A. (2015) An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex J Allergy Clin. Immunol; 135(4):998-1007. PMID: 25312759

29. Wild C.P., Bucher J.R., de Jong B.W., Dillner J., von Gertten C., Groopman J.D., Herceg Z., Holmes E., Holmila R., Olsen J.H., Ringborg U., Scalbert A., Shibata T., Smith M.T., Ulrich C., Vineis P., McLaughlin J. (2015) Translational Cancer Research: Balancing Prevention and Treatment to Combat Cancer Globally J Natl Cancer Inst; 107(1):353. PMID: 25515230

30. Lee H. S. (2015) Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood Nutrients; 7(11):9492-507. PMID: 26593940

31. Sahay D., Leblanc R., Grunewald T.G., Ambatipudi S., Ribeiro J., Clezardin P., Peyruchaud O. (2015) The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer Oncotarget; 6(24):20604-20620. PMID: 26098771

32. Paltiel O., Tikellis G., Linet M., Golding J., Lemeshow S., Phillips G., Lamb K., Stoltenberg C., Haberg S.E., Strom M., Granstrom C., Northstone K., Klebanoff M., Ponsonby A.L., Milne E., Pedersen M., Kogevinas M., Ha E., Dwyer T. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C) Paediatr. Perinat. Epidemiol; 29(4):335-345. PMID: 25989709

33. Caygill C.P., Gatenby P.A., Herceg Z., Lima S.C., Pinto L.F., Watson A., Wu M.S. (2014) Comparative genomic analysis of esophageal cancers Ann N. Y. Acad Sci; 1325(1):69-76.

34. Ghantous A., Saffery R., Cros M.P., Ponsonby A.L., Hirschfeld S., Kasten C., Dwyer T., Herceg Z., Hernandez-Vargas H. (2014) Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling BMC. Biotechnol; 60.

35. Guillot C., Favaudon V., Herceg Z., Sagne C., Sauvaigo S., Merle P., Hall J., Chemin I. (2014) PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models BMC. Cancer; 603.

36. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC. Genomics; 435.

37. Lee H.S., Herceg Z. (2014) The epigenome and cancer prevention: A complex story of dietary supplementation Cancer Lett; 342(2):275-284.

38. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650.

39. Leduc C., Chemin G., Puget N., Sawan C., Moutahir M., Herceg Z., Khamlichi A.A. (2014) Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells Cell Cycle; 13(10):1583-1589.

40. Tapias A., Zhou Z.W., Shi Y., Chong Z., Wang P., Groth M., Platzer M., Huttner W., Herceg Z., Yang Y.G., Wang Z.Q. (2014) Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions Cell Stem Cell; 14(5):632-643.

41. Guillot C., Hall J., Herceg Z., Merle P., Chemin I. (2014) Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy Clin Res Hepatol. Gastroenterol; 38(2):137-142.

42. Hedley C., Sriraksa R., Showeil R., Van Noorden S., El-Bahrawy M. (2014) The frequency and significance of WT-1 expression in serous endometrial carcinoma Hum Pathol; 45(9):1879-1884.

43. Durandy A, Kracker S., Schwartzentruber J., Cuenin C., Herceg Z., Jabado N., Nejentsev S, Fischer A. (2014) Immunoglobulin class-switch recombination deficiencies. Selected Abstracts from the 100th J Project Meeting, Antalya, Turkey, March 12-14, 2014 J Clin Immunol; 34(6):696.

44. McCloskey K., Sun C., Pezic A., Cochrane J., Morley R., Vuillermin P., Burgner D., Dwyer T., Ponsonby A.L. (2014) The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study J Dev. Orig. Health Dis; 5(4):307-313.

45. Thomas N.E., Kricker A., Waxweiler W.T., Dillon P.M., Busam K.J., From L., Groben P.A., Armstrong B.K., Anton-Culver H., Gruber S.B., Marrett L.D., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Orlow I., Paine S., Ollila D.W., Reiner A.S., Luo L., Hao H., Frank J.S., Begg C.B., Berwick M. (2014) Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas: A Population-Based Study JAMA Dermatol; 150(12):1306-1314.

46. Ponsonby A.L., Dwyer T. (2014) Statistics: Biomedicine must look beyond P values Nature; 507(7491):169.

47. Herceg Z. (2014) Cancer prevention potential of diet and dietary supplements in epigenome modulation ; 43-70.

48. Ichim G., Mola M., Finkbeiner M.G., Cros M.P., Herceg Z., Hernandez-Vargas H. (2014) The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene; 33(2):181-192.

49. Lee H.S., Barraza-Villarreal A., Biessy C., Duarte-Salles T., Sly P.D., Ramakrishnan U., Rivera J., Herceg Z., Romieu I. (2014) Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants Physiol Genomics; 46(23):851-857.

50. Berwick M., MacArthur J., Orlow I., Kanetsky P., Begg C.B., Luo L., Reiner A., Sharma A., Armstrong B.K., Kricker A., Cust A.E., Marrett L.D., Gruber S.B., Anton-Culver H., Zanetti R., Rosso S., Gallagher R.P., Dwyer T., Venn A., Busam K., From L., White K., Thomas N.E. (2014) MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors Pigment Cell Melanoma Res; 27(3):485-488.

51. Wang N., Tikellis G., Sun C., Pezic A., Wang L., Wells J.C., Cochrane J., Ponsonby A.L., Dwyer T. (2014) The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio Placenta; 35(7):437-441.

52. Ecsedi S., Hernandez-Vargas H., Lima S.C., Vizkeleti L., Toth R., Lazar V., Koroknai V., Kiss T., Emri G., Herceg Z., Adany R., Balazs M. (2014) DNA methylation characteristics of primary melanomas with distinct biological behaviour PLoS ONE; 9(5):e96612.

53. Siouda M., Frecha C., Accardi R., Yue J., Cuenin C., Gruffat H., Manet E., Herceg Z., Sylla B.S., Tommasino M. (2014) Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression PLoS Pathog; 10(5):e1004125.

54. Lee H.S., Barraza-Villarreal A., Hernandez-Vargas H., Sly P.D., Biessy C., Ramakrishnan U., Romieu I., Herceg Z. (2013) Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study Am. J Clin Nutr; 98(2):480-487.

55. Lee H.S., Hernandez-Vargas H., Biessy C., Romieu I., Herceg Z., Barraza-Villarreal A., Sly P.D., Ramakrishnan U. (2013) Am. J Clin Nutr; 98(6):1595-1596.

56. Umer M., Herceg Z. (2013) Deciphering the epigenetic code: an overview of DNA methylation analysis methods Antioxid. Redox. Signal; 18(15):1972-1986.

57. Ouzounova M., Vuong T., Ancey P.B., Ferrand M., Durand G., Le-Calvez Kelm F., Croce C., Matar C., Herceg Z., Hernandez-Vargas H. (2013) MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells BMC. Genomics; 139.

58. Khoury M.J., Lam T.K., Ioannidis J.P., Hartge P., Spitz M.R., Buring J.E., Chanock S.J., Croyle R.T., Goddard K.A., Ginsburg G.S., Herceg Z., Hiatt R.A., Hoover R.N., Hunter D.J., Kramer B.S., Lauer M.S., Meyerhardt J.A., Olopade O.I., Palmer J.R., Sellers T.A., Seminara D., Ransohoff D.F., Rebbeck T.R., Tourassi G., Winn D.M., Zauber A., Schully S.D. (2013) Transforming epidemiology for 21st century medicine and public health Cancer Epidemiol Biomarkers Prev; 22(4):508-516.

59. Herceg Z., Lambert M.P., van Veldhoven K., Demetriou C., Vineis P., Smith M.T., Straif K., Wild C.P. (2013) Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation Carcinogenesis; 34(9):1955-1967.

60. Browne A., Sriraksa R., Guney T., Rama N., Van Noorden S., Curry E., Gabra H., Stronach E., El-Bahrawy M. (2013) Differential expression of IL-8 and IL-8 receptors in benign, borderline and malignant ovarian epithelial tumours Cytokine; 64(1):413-421.

61. Gospodinov A., Herceg Z. (2013) Chromatin structure in double strand break repair DNA Repair (Amst); 12(10):800-810.

62. Ghantous A., Sinjab A., Herceg Z., Darwiche N. (2013) Parthenolide: from plant shoots to cancer roots Drug Discov. Today; 18(17):894-905.

63. Wild C.P., Scalbert A., Herceg Z. (2013) Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk Environ. Mol. Mutagen; 54(7):480-499.

64. Aury-Landas J., Bougeard G., Castel H., Hernandez-Vargas H., Drouet A., Latouche J.B., Schouft M.T., Ferec C., Leroux D., Lasset C., Coupier I., Caron O., Herceg Z., Frebourg T., Flaman J.M. (2013) Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours Eur. J Hum Genet; 21(12):1369-1376.

65. Ecsedi S.I., Hernandez-Vargas H., Lima S.C., Herceg Z., Adany R., Balazs M. (2013) Transposable hypomethylation is associated with metastatic capacity of primary melanomas Int. J Clin Exp. Pathol; 6(12):2943-2948.

66. Thomas N.E., Busam K.J., From L., Kricker A., Armstrong B.K., Anton-Culver H., Gruber S.B., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Groben P.A., Hao H., Orlow I., Reiner A.S., Luo L., Paine S., Ollila D.W., Wilcox H., Begg C.B., Berwick M. (2013) Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study J Clin Oncol; 31(33):4252-4259.

67. Gospodinov A., Herceg Z. (2013) Shaping chromatin for repair Mutat Res; 752(1):45-60.

68. Aushev V.N., Zborovskaya I.B., Laktionov K.K., Girard N., Cros M.P., Herceg Z., Krutovskikh V. (2013) Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma PLoS ONE; 8(10):e78649.

69. Demetriou C.A., Chen J., Polidoro S., van Veldhoven K., Cuenin C., Campanella G., Brennan K., Clavel-Chapelon F., Dossus L., Kvaskoff M., Drogan D., Boeing H., Kaaks R., Risch A., Trichopoulos D., Lagiou P., Masala G., Sieri S., Tumino R., Panico S., Quiros J.R., Sanchez Perez M.J., Amiano P., Huerta Castano J.M., Ardanaz E., Onland-Moret C., Peeters P., Khaw K.T., Wareham N., Key T.J., Travis R.C., Romieu I., Gallo V., Gunter M., Herceg Z., Kyriacou K., Riboli E., Flanagan J.M., Vineis P. (2013) Methylome analysis and epigenetic changes associated with menarcheal age PLoS ONE; 8(11):e79391.

70. El Hajj H., Ali J., Ghantous A., Hodroj D., Daher A., Zibara K., Journo C., Otrock Z., Zaatari G., Mahieux R., El Sabban M., Bazarbachi A., Abou Merhi R. (2013) Combination of arsenic and interferon-alpha inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas PLoS ONE; 8(11):e79474.

71. Rakosy Z., Ecsedi S., Toth R., Vizkeleti L., Hernandez-Vargas H., Lazar V., Emri G., Szatmari I., Herceg Z., Adany R., Balazs M. (2013) Integrative genomics identifies gene signature associated with melanoma ulceration PLoS ONE; 8(1):e54958.

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