Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Previous Publications - All publications 2015-2011

1. da Costa A.N., Plymoth A., Santos-Silva D., Ortiz-Cuaran S., Camey S., Guilloreau P., Sangrajrang S., Khuhaprema T., Mendy M., Lesi O.A., Chang H.K., Oh J.K., Lee D.H., Shin H.R., Kirk G.D., Merle P., Beretta L., Hainaut P. (2015) Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma International journal of cancer; 136(1):172-181. PMID: 24803312

2. Wild C.P., Bucher J.R., de Jong B.W., Dillner J., von Gertten C., Groopman J.D., Herceg Z., Holmes E., Holmila R., Olsen J.H., Ringborg U., Scalbert A., Shibata T., Smith M.T., Ulrich C., Vineis P., McLaughlin J. (2015) Translational Cancer Research: Balancing Prevention and Treatment to Combat Cancer Globally Journal of the National Cancer Institute; 107(1):. PMID: 25515230

3. Lee H.S., Barraza-Villarreal A., Biessy C., Duarte-Salles T., Sly P.D., Ramakrishnan U., Rivera J., Herceg Z., Romieu I. (2014) Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants Physiol Genomics; 46(23):851-857. PMID: 25293351

4. Thomas N.E., Kricker A., Waxweiler W.T., Dillon P.M., Busam K.J., From L., Groben P.A., Armstrong B.K., Anton-Culver H., Gruber S.B., Marrett L.D., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Orlow I., Paine S., Ollila D.W., Reiner A.S., Luo L., Hao H., Frank J.S., Begg C.B., Berwick M. (2014) Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas: A Population-Based Study JAMA Dermatol; 150(12):1306-1314. PMID: 25162299

5. Caygill C.P., Gatenby P.A., Herceg Z., Lima S.C., Pinto L.F., Watson A., Wu M.S. (2014) Comparative genomic analysis of esophageal cancers Ann N.Y.Acad Sci; 1325(1):69-76. PMID: 25266016

6. Hedley C., Sriraksa R., Showeil R., Van Noorden S., El-Bahrawy M. (2014) The frequency and significance of WT-1 expression in serous endometrial carcinoma Hum Pathol; 45(9):1879-1884. PMID: 25033726

7. McCloskey K., Sun C., Pezic A., Cochrane J., Morley R., Vuillermin P., Burgner D., Dwyer T., Ponsonby A.L. (2014) The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study J Dev.Orig.Health Dis; 5(4):307-313. PMID: 24965137

8. Wang N., Tikellis G., Sun C., Pezic A., Wang L., Wells J.C., Cochrane J., Ponsonby A.L., Dwyer T. (2014) The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio Placenta; 35(7):437-441. PMID: 24816479

9. Berwick M., MacArthur J., Orlow I., Kanetsky P., Begg C.B., Luo L., Reiner A., Sharma A., Armstrong B.K., Kricker A., Cust A.E., Marrett L.D., Gruber S.B., Anton-Culver H., Zanetti R., Rosso S., Gallagher R.P., Dwyer T., Venn A., Busam K., From L., White K., Thomas N.E. (2014) MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors Pigment Cell Melanoma Res; 27(3):485-488. PMID: 24406078

10. Leduc C., Chemin G., Puget N., Sawan C., Moutahir M., Herceg Z., Khamlichi A.A. (2014) Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells Cell Cycle; 13(10):1583-1589. PMID: 24675885

11. Siouda M., Frecha C., Accardi R., Yue J., Cuenin C., Gruffat H., Manet E., Herceg Z., Sylla B.S., Tommasino M. (2014) Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression PLoS Pathog.; 10(5):e1004125. PMID: 24809689

12. Tapias A., Zhou Z.W., Shi Y., Chong Z., Wang P., Groth M., Platzer M., Huttner W., Herceg Z., Yang Y.G., Wang Z.Q. (2014) Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions Cell Stem Cell; 14(5):632-643. PMID: 24792116

13. Guillot C., Hall J., Herceg Z., Merle P., Chemin I. (2014) Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy Clin Res Hepatol.Gastroenterol; 38(2):137-142. PMID: 23953496

14. Ponsonby A.L., Dwyer T. (2014) Statistics: Biomedicine must look beyond P values Nature; 507(7491):169. PMID: 24622193

15. Ichim G., Mola M., Finkbeiner M.G., Cros M.P., Herceg Z., Hernandez-Vargas H. (2014) The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene; 33(2):181-192. PMID: 23318449

16. Lee H.S., Herceg Z. (2014) The epigenome and cancer prevention: A complex story of dietary supplementation Cancer Lett.; 342(2):275-284. PMID: 22266189

17. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650. PMID: 24163401

18. Ecsedi S., Hernandez-Vargas H., Lima S.C., Vizkeleti L., Toth R., Lazar V., Koroknai V., Kiss T., Emri G., Herceg Z., Adany R., Balazs M. (2014) DNA methylation characteristics of primary melanomas with distinct biological behaviour PLoS ONE; 9(5):e96612. PMID: 24832207

19. Ghantous A., Saffery R., Cros M.P., Ponsonby A.L., Hirschfeld S., Kasten C., Dwyer T., Herceg Z., Hernandez-Vargas H. (2014) Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling BMC.Biotechnol.; 60. PMID: 24980254

20. Guillot C., Favaudon V., Herceg Z., Sagne C., Sauvaigo S., Merle P., Hall J., Chemin I. (2014) PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models BMC.Cancer; 603. PMID: 25139788

21. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC.Genomics; 435. PMID: 24898317

22. Aury-Landas J., Bougeard G., Castel H., Hernandez-Vargas H., Drouet A., Latouche J.B., Schouft M.T., Ferec C., Leroux D., Lasset C., Coupier I., Caron O., Herceg Z., Frebourg T., Flaman J.M. (2013) Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours Eur.J Hum Genet.; 21(12):1369-1376. PMID: 23612572

23. Lee H.S., Hernandez-Vargas H., Biessy C., Romieu I., Herceg Z., Barraza-Villarreal A., Sly P.D., Ramakrishnan U. (2013) Am.J Clin Nutr.; 98(6):1595-1596. PMID: 24259359

24. Thomas N.E., Busam K.J., From L., Kricker A., Armstrong B.K., Anton-Culver H., Gruber S.B., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Groben P.A., Hao H., Orlow I., Reiner A.S., Luo L., Paine S., Ollila D.W., Wilcox H., Begg C.B., Berwick M. (2013) Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study Journal of clinical oncology; 31(33):4252-4259. PMID: 24127443

25. Browne A., Sriraksa R., Guney T., Rama N., Van Noorden S., Curry E., Gabra H., Stronach E., El-Bahrawy M. (2013) Differential expression of IL-8 and IL-8 receptors in benign, borderline and malignant ovarian epithelial tumours Cytokine; 64(1):413-421. PMID: 23727325

26. Gospodinov A., Herceg Z. (2013) Chromatin structure in double strand break repair DNA Repair; 12(10):800-810. PMID: 23919923

27. Ghantous A., Sinjab A., Herceg Z., Darwiche N. (2013) Parthenolide: from plant shoots to cancer roots Drug Discov.Today; 18(17):894-905. PMID: 23688583

28. Herceg Z., Lambert M.P., van Veldhoven K., Demetriou C., Vineis P., Smith M.T., Straif K., Wild C.P. (2013) Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation Carcinogenesis; 34(9):1955-1967. PMID: 23749751

29. Lee H.S., Barraza-Villarreal A., Hernandez-Vargas H., Sly P.D., Biessy C., Ramakrishnan U., Romieu I., Herceg Z. (2013) Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study Am.J Clin Nutr.; 98(2):480-487. PMID: 23761484

30. Wild C.P., Scalbert A., Herceg Z. (2013) Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk Environ.Mol.Mutagen.; 54(7):480-499. PMID: 23681765

31. Sawan C., Hernandez-Vargas H., Murr R., Lopez F., Vaissiere T., Ghantous A.Y., Cuenin C., Imbert J., Wang Z.Q., Ren B., Herceg Z. (2013) Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells Stem Cells; 31(5):979-991. PMID: 23362228

32. Umer M., Herceg Z. (2013) Deciphering the epigenetic code: an overview of DNA methylation analysis methods Antioxid.Redox.Signal.; 18(15):1972-1986. PMID: 23121567

33. Khoury M.J., Lam T.K., Ioannidis J.P., Hartge P., Spitz M.R., Buring J.E., Chanock S.J., Croyle R.T., Goddard K.A., Ginsburg G.S., Herceg Z., Hiatt R.A., Hoover R.N., Hunter D.J., Kramer B.S., Lauer M.S., Meyerhardt J.A., Olopade O.I., Palmer J.R., Sellers T.A., Seminara D., Ransohoff D.F., Rebbeck T.R., Tourassi G., Winn D.M., Zauber A., Schully S.D. (2013) Transforming epidemiology for 21st century medicine and public health Cancer epidemiology, biomarkers & prevention; 22(4):508-516. PMID: 23462917

34. Genevois A.L., Ichim G., Coissieux M.M., Lambert M.P., Lavial F., Goldschneider D., Jarrosson-Wuilleme L., Lepinasse F., Gouysse G., Herceg Z., Scoazec J.Y., Tauszig-Delamasure S., Mehlen P. (2013) Dependence receptor TrkC is a putative colon cancer tumor suppressor Proceedings of the National Academy of Sciences of the United States of America; 110(8):3017-3022. PMID: 23341610

35. Gospodinov A., Herceg Z. (2013) Shaping chromatin for repair Mutation research; 752(1):45-60. PMID: 23085398

36. Aushev V.N., Zborovskaya I.B., Laktionov K.K., Girard N., Cros M.P., Herceg Z., Krutovskikh V. (2013) Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma PLoS ONE; 8(10):e78649. PMID: 24130905

37. Demetriou C.A., Chen J., Polidoro S., van Veldhoven K., Cuenin C., Campanella G., Brennan K., Clavel-Chapelon F., Dossus L., Kvaskoff M., Drogan D., Boeing H., Kaaks R., Risch A., Trichopoulos D., Lagiou P., Masala G., Sieri S., Tumino R., Panico S., Quiros J.R., Sanchez Perez M.J., Amiano P., Huerta Castano J.M., Ardanaz E., Onland-Moret C., Peeters P., Khaw K.T., Wareham N., Key T.J., Travis R.C., Romieu I., Gallo V., Gunter M., Herceg Z., Kyriacou K., Riboli E., Flanagan J.M., Vineis P. (2013) Methylome analysis and epigenetic changes associated with menarcheal age PLoS ONE; 8(11):e79391. PMID: 24278132

38. Ecsedi S.I., Hernandez-Vargas H., Lima S.C., Herceg Z., Adany R., Balazs M. (2013) Transposable hypomethylation is associated with metastatic capacity of primary melanomas Int.J Clin Exp.Pathol; 6(12):2943-2948. PMID: 24294382

39. El Hajj H., Ali J., Ghantous A., Hodroj D., Daher A., Zibara K., Journo C., Otrock Z., Zaatari G., Mahieux R., El Sabban M., Bazarbachi A., Abou Merhi R. (2013) Combination of arsenic and interferon-alpha inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas PLoS ONE; 8(11):e79474. PMID: 24250827

40. Ouzounova M., Vuong T., Ancey P.B., Ferrand M., Durand G., Le-Calvez Kelm F., Croce C., Matar C., Herceg Z., Hernandez-Vargas H. (2013) MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells BMC.Genomics; 139. PMID: 23445407

41. Rakosy Z., Ecsedi S., Toth R., Vizkeleti L., Hernandez-Vargas H., Lazar V., Emri G., Szatmari I., Herceg Z., Adany R., Balazs M. (2013) Integrative genomics identifies gene signature associated with melanoma ulceration PLoS ONE; 8(1):e54958. PMID: 23383013

42. da Costa N.M., Hautefeuille A., Cros M.P., Melendez M.E., Waters T., Swann P., Hainaut P., Pinto L.F. (2012) Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53 Cell Cycle; 11(24):4570-4578. PMID: 23165212

43. Nogueira da Costa A., Herceg Z. (2012) Detection of cancer-specific epigenomic changes in biofluids: Powerful tools in biomarker discovery and application Mol Oncol; 6(6):704-715. PMID: 22925902

44. Siouda M., Yue J., Shukla R., Guillermier S., Herceg Z., Creveaux M., Accardi R., Tommasino M., Sylla B.S. (2012) Transcriptional Regulation of the Human Tumor Suppressor DOK1 by E2F1 Molecular and cellular biology; 32(23):4877-4890. PMID: 23028047

45. Kesminiene A., Evrard A.S., Ivanov V.K., Malakhova I.V., Kurtinaitise J., Stengrevics A., Tekkel M., Chekin S., Drozdovitch V., Gavrilin Y., Golovanov I., Kryuchkov V.P., Maceika E., Mirkhaidarov A.K., Polyakov S., Tenet V., Tukov A.R., Byrnes G., Cardis E. (2012) Risk of Thyroid Cancer among Chernobyl Liquidators Radiation research; 178(5):425-436. PMID: 22998226

46. Mahabir S., Aagaard K., Anderson L.M., Herceg Z., Hiatt R.A., Hoover R.N., Linet M.S., Medina D., Potischman N., Tretli S., Trichopoulos D., Troisi R. (2012) Challenges and opportunities in research on early-life events/exposures and cancer development later in life Cancer causes & control : CCC; 23(6):983-990. PMID: 22527169

47. Saulnier A., Vaissiere T., Yue J., Siouda M., Malfroy M., Accardi R., Creveaux M., Sebastian S., Shahzad N., Gheit T., Hussain I., Torrente M., Maffini F.A., Calabrese L., Chiesa F., Cuenin C., Shukla R., Fathallah I., Matos E., Daudt A., Koifman S., Wunsch-Filho V., Menezes A.M., Curado M.P., Zaridze D., Boffetta P., Brennan P., Tommasino M., Herceg Z., Sylla B.S. (2012) Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers International journal of cancer; 130(11):2484-2494. PMID: 21796618

48. Xu X., Gammon M.D., Hernandez-Vargas H., Herceg Z., Wetmur J.G., Teitelbaum S.L., Bradshaw P.T., Neugut A.I., Santella R.M., Chen J. (2012) DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study FASEB journal; 26(6):2657-2666. PMID: 22371529

49. Kaur P., Mani S., Cros M.P., Scoazec J.Y., Chemin I., Hainaut P., Herceg Z. (2012) Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma Tumour biology; 33(2):325-336. PMID: 22351518

50. Mani S., Szymanska K., Cuenin C., Zaridze D., Balassiano K., Lima S.C., Matos E., Daudt A., Koifman S., Filho V.W., Menezes A.M., Curado M.P., Ferro G., Vaissiere T., Sylla B.S., Tommasino M., Pinto L.F., Boffetta P., Hainaut P., Brennan P., Herceg Z. (2012) DNA methylation changes associated with risk factors in tumors of the upper aerodigestive tract Epigenetics; 7(3):270-277. PMID: 22430803

51. Zoldos V., Horvat T., Novokmet M., Cuenin C., Muzinic A., Pucic M., Huffman J.E., Gornik O., Polasek O., Campbell H., Hayward C., Wright A.F., Rudan I., Owen K., McCarthy M.I., Herceg Z., Lauc G. (2012) Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome Epigenetics; 7(2):164-172. PMID: 22395466

52. Martin M., Herceg Z. (2012) From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms Genome Med; 4(1):8. PMID: 22293089

53. Balassiano K., Lima S., Jenab M., Overvad K., Tjonneland A., Boutron-Ruault M.C., Clavel-Chapelon F., Canzian F., Kaaks R., Boeing H., Meidtner K., Trichopoulou A., Laglou P., Vineis P., Panico S., Palli D., Grioni S., Tumino R., Lund E., Bueno-de-Mesquita H.B., Numans M.E., Peeters P.H., Ramon Quiros J., Sanchez M.A., Navarro C., Ardanaz E., Dorronsoro M., Hallmans G., Stenling R., Ehrnstrom R., Regner S., Allen N.E., Travis R.C., Khaw K.T., Offerhaus G.J., Sala N., Riboli E., Hainaut P., Scoazec J.Y., Sylla B.S., Gonzalez C.A., Herceg Z. (2011) Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Cancer letters; 311(1):85-95. PMID: 21831520

54. Gospodinov A., Vaissiere T., Krastev D.B., Legube G., Anachkova B., Herceg Z. (2011) Mammalian Ino80 Mediates Double-Strand Break Repair through Its Role in DNA End Strand Resection Molecular and cellular biology; 31(23):4735-4745. PMID: 21947284

55. Krutovskikh V., Partensky C. (2011) [New insights in oncology: Epigenetics and cancer stem cells] Cancer Radiother; 15(8):716-722. PMID: 22079560

56. Lima S.C., Hernandez-Vargas H., Simao T., Durand G., Kruel C.D., Le Calvez-Kelm F., Ribeiro Pinto L.F., Herceg Z. (2011) Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers Epigenetics; 6(10):1217-1227. PMID: 21946330

57. Krais A.M., Hautefeuille A.H., Cros M.P., Krutovskikh V., Tournier J.M., Birembaut P., Thepot A., Paliwal A., Herceg Z., Boffetta P., Brennan P., Hainaut P.L. (2011) CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression Carcinogenesis; 32(9):1388-1395. PMID: 21586512

58. Scoccianti C., Ricceri F., Ferrari P., Cuenin C., Sacerdote C., Polidoro S., Jenab M., Hainaut P., Vineis P., Herceg Z. (2011) Methylation patterns in sentinel genes in peripheral blood cells of heavy smokers: Influence of cruciferous vegetables in an intervention study Epigenetics; 6(9):1114-1119. PMID: 21822058

59. Yue J., Shukla R., Accardi R., Zanella-Cleon I., Siouda M., Cros M.P., Krutovskikh V., Hussain I., Niu Y., Hu S., Becchi M., Jurdic P., Tommasino M., Sylla B.S. (2011) Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A Journal of virology; 85(17):8477-8494. PMID: 21697493

60. Herceg Z., Vaissiere T. (2011) Epigenetic mechanisms and cancer: An interface between the environment and the genome Epigenetics; 6(7):804-819. PMID: 21758002

61. Shukla R., Yue J., Siouda M., Gheit T., Hantz O., Merle P., Zoulim F., Krutovskikh V., Tommasino M., Sylla B.S. (2011) Proinflammatory cytokine TNF-alpha increases the stability of hepatitis B virus X protein through NF-kappaB signaling Carcinogenesis; 32(7):978-985. PMID: 21459755

62. Herceg Z., Paliwal A. (2011) Epigenetic mechanisms in hepatocellular carcinoma: How environmental factors influence the epigenome Mutation research.Reviews in Mutation Research; 727(3):55-61. PMID: 21514401

63. Hernandez-Vargas H., Ouzounova M., Le Calvez-Kelm F., Lambert M.P., McKay-Chopin S., Tavtigian S.V., Puisieux A., Matar C., Herceg Z. (2011) Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells Epigenetics; 6(4):428-439. PMID: 21266853

64. Lambert M.P., Paliwal A., Vaissiere T., Chemin I., Zoulim F., Tommasino M., Hainaut P., Sylla B., Scoazec J.Y., Tost J., Herceg Z. (2011) Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake J Hepatol; 54(4):705-715. PMID: 21146512

65. Auclair J., Vaissiere T., Desseigne F., Lasset C., Bonadona V., Giraud S., Saurin J.C., Joly M.O., Leroux D., Faivre L., Audoynaud C., Montmain G., Ruano E., Herceg Z., Puisieux A., Wang Q. (2011) Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles Genes, chromosomes & cancer; 50(3):178-185. PMID: 21213371

66. Shukla V., Cuenin C., Dubey N., Herceg Z. (2011) Loss of histone acetyltransferase cofactor transformation/transcription domain-associated protein impairs liver regeneration after toxic injury Hepatology; 53(3):954-963. PMID: 21319192

67. Vineis P., Chuang S.C., Vaissiere T., Cuenin C., Ricceri F., Johansson M., Ueland P., Brennan P., Herceg Z. (2011) DNA methylation changes associated with cancer risk factors and blood levels of vitamin metabolites in a prospective study Epigenetics; 6(2):195-201. PMID: 20978370

68. Sincic N., Herceg Z. (2011) DNA methylation and cancer: ghosts and angels above the genes Current opinion in oncology; 23(1):69-76. PMID: 21119515

69. Herceg Z., Hernandez-Vargas H. (2011) New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research Epigenomics; 3(4):383-386. PMID: 22126196

70. Thepot A., Desanlis A., Venet E., Thivillier L., Justin V., Morel A.P., Defraipont F., Till M., Krutovskikh V., Tommasino M., Damour O., Hainaut P. (2011) Assessment of transformed properties in vitro and of tumorigenicity in vivo in primary keratinocytes cultured for epidermal sheet transplantation J Skin Cancer; 936546. PMID: 21188234