Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Previous Publications - All publications 2017-2013

1. Degli Esposti D., Sklias A., Lima S. C., Beghelli-de la Forest Divonne S., Cahais V., Fernandez-Jimenez N., Cros M. P., Ecsedi S., Cuenin C., Bouaoun L., Byrnes G., Accardi R., Sudaka A., Giordanengo V., Hernandez-Vargas H., Pinto L. F., Van Obberghen-Schilling E., Herceg Z. (2017) Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas Genome Med; 9(1):33. PMID: 28381277

2. Ambatipudi S., Horvath S., Perrier F., Cuenin C., Hernandez-Vargas H., Le Calvez-Kelm F., Durand G., Byrnes G., Ferrari P., Bouaoun L., Sklias A., Chajes V., Overvad K., Severi G., Baglietto L., Clavel-Chapelon F., Kaaks R., Barrdahl M., Boeing H., Trichopoulou A., Lagiou P., Naska A., Masala G., Agnoli C., Polidoro S., Tumino R., Panico S., Dolle M., Peeters P. H., Onland-Moret N. C., Sandanger T. M., Nost T. H., Weiderpass E., Quiros J. R., Agudo A., Rodriguez-Barranco M., Huerta Castano J. M., Barricarte A., Fernandez A. M., Travis R. C., Vineis P., Muller D. C., Riboli E., Gunter M., Romieu I., Herceg Z. (2017) DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility Eur J Cancer; 299-307. PMID: 28259012

3. Vineis P., Chadeau-Hyam M., Gmuender H., Gulliver J., Herceg Z., Kleinjans J., Kogevinas M., Kyrtopoulos S., Nieuwenhuijsen M., Phillips D. H., Probst-Hensch N., Scalbert A., Vermeulen R., Wild C. P. (2017) The exposome in practice: Design of the EXPOsOMICS project Int J Hyg Environ Health; 220(2):142-151. PMID: 27576363

4. Holmila R., Sklias A., Muller D. C., Degli Esposti D., Guilloreau P., McKay J., Sangrajrang S., Srivatanakul P., Hainaut P., Merle P., Herceg Z., Nogueira da Costa A. (2017) Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma PLoS ONE; 12(3):e0174265. PMID: 28333958

5. Beltrami C. M., Dos Reis M. B., Barros-Filho M. C., Marchi F. A., Kuasne H., Pinto C. A. L., Ambatipudi S., Herceg Z., Kowalski L. P., Rogatto S. R. (2017) Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas Clin Epigenetics; 45. PMID: 28469731

6. Joehanes R., Just A. C., Marioni R. E., Pilling L. C., Reynolds L. M., Mandaviya P. R., Guan W., Xu T., Elks C. E., Aslibekyan S., Moreno-Macias H., Smith J. A., Brody J. A., Dhingra R., Yousefi P., Pankow J. S., Kunze S., Shah S. H., McRae A. F., Lohman K., Sha J., Absher D. M., Ferrucci L., Zhao W., Demerath E. W., Bressler J., Grove M. L., Huan T., Liu C., Mendelson M. M., Yao C., Kiel D. P., Peters A., Wang-Sattler R., Visscher P. M., Wray N. R., Starr J. M., Ding J., Rodriguez C. J., Wareham N. J., Irvin M. R., Zhi D., Barrdahl M., Vineis P., Ambatipudi S., Uitterlinden A. G., Hofman A., Schwartz J., Colicino E., Hou L., Vokonas P. S., Hernandez D. G., Singleton A. B., Bandinelli S., Turner S. T., Ware E. B., Smith A. K., Klengel T., Binder E. B., Psaty B. M., Taylor K. D., Gharib S. A., Swenson B. R., Liang L., DeMeo D. L., O'Connor G. T., Herceg Z., Ressler K. J., Conneely K. N., Sotoodehnia N., Kardia S. L., Melzer D., Baccarelli A. A., van Meurs J. B., Romieu I., Arnett D. K., Ong K. K., Liu Y., Waldenberger M., Deary I. J., Fornage M., Levy D., London S. J. (2016) Epigenetic Signatures of Cigarette Smoking Circ Cardiovasc Genet; 9(5):436-447. PMID: 27651444

7. Esposti D. D., Hernandez-Vargas H., Voegele C., Fernandez-Jimenez N., Forey N., Bancel B., Le Calvez-Kelm F., McKay J., Merle P., Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing Oncotarget; 7(22):31862-77. PMID: 26887054

8. Ambatipudi S., Cuenin C., Hernandez-Vargas H., Ghantous A., Le Calvez-Kelm F., Kaaks R., Barrdahl M., Boeing H., Aleksandrova K., Trichopoulou A., Lagiou P., Naska A., Palli D., Krogh V., Polidoro S., Tumino R., Panico S., Bueno-de-Mesquita B., Peeters P. H., Quiros J. R., Navarro C., Ardanaz E., Dorronsoro M., Key T., Vineis P., Murphy N., Riboli E., Romieu I., Herceg Z. (2016) Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study Epigenomics; 8(5):599-618. PMID: 26864933

9. van der Mei I., Lucas R. M., Taylor B. V., Valery P. C., Dwyer T., Kilpatrick T. J., Pender M. P., Williams D., Chapman C., Otahal P., Ponsonby A. L. (2016) Population attributable fractions and joint effects of key risk factors for multiple sclerosis Mult Scler; 22(4):461-9. PMID: 26199349

10. Joubert B. R., Felix J. F., Yousefi P., Bakulski K. M., Just A. C., Breton C., Reese S. E., Markunas C. A., Richmond R. C., Xu C. J., Kupers L. K., Oh S. S., Hoyo C., Gruzieva O., Soderhall C., Salas L. A., Baiz N., Zhang H., Lepeule J., Ruiz C., Ligthart S., Wang T., Taylor J. A., Duijts L., Sharp G. C., Jankipersadsing S. A., Nilsen R. M., Vaez A., Fallin M. D., Hu D., Litonjua A. A., Fuemmeler B. F., Huen K., Kere J., Kull I., Munthe-Kaas M. C., Gehring U., Bustamante M., Saurel-Coubizolles M. J., Quraishi B. M., Ren J., Tost J., Gonzalez J. R., Peters M. J., Haberg S. E., Xu Z., van Meurs J. B., Gaunt T. R., Kerkhof M., Corpeleijn E., Feinberg A. P., Eng C., Baccarelli A. A., Benjamin Neelon S. E., Bradman A., Merid S. K., Bergstrom A., Herceg Z., Hernandez-Vargas H., Brunekreef B., Pinart M., Heude B., Ewart S., Yao J., Lemonnier N., Franco O. H., Wu M. C., Hofman A., McArdle W., Van der Vlies P., Falahi F., Gillman M. W., Barcellos L. F., Kumar A., Wickman M., Guerra S., Charles M. A., Holloway J., Auffray C., Tiemeier H. W., Smith G. D., Postma D., Hivert M. F., Eskenazi B., Vrijheid M., Arshad H., Anto J. M., Dehghan A., Karmaus W., Annesi-Maesano I., Sunyer J., Ghantous A., Pershagen G., Holland N., Murphy S. K., DeMeo D. L., Burchard E. G., Ladd-Acosta C., Snieder H., Nystad W., Koppelman G. H., Relton C. L., Jaddoe V. W., Wilcox A., Melen E., London S. J. (2016) DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis Am J Hum Genet; 98(4):680-96. PMID: 27040690

11. Showeil R., Romano C., Valganon M., Lambros M., Trivedi P., Van Noorden S., Sriraksa R., El-Kaffash D., El-Etreby N., Natrajan R., Foroni L., Osborne R., El-Bahrawy M. (2016) The status of epidermal growth factor receptor in borderline ovarian tumours Oncotarget; 7(9):10568-77. PMID: 26870997

12. Vuong T., Mallet J. F., Ouzounova M., Rahbar S., Hernandez-Vargas H., Herceg Z., Matar C. (2016) Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation J Transl Med; 14(13):1-12. PMID: 26762586

13. Herceg Z. (2016) Epigenetic Mechanisms as an Interface Between the Environment and Genome Adv Exp Med Biol; 3-15. PMID: 27343085

14. Grandin M., Mathot P., Devailly G., Bidet Y., Ghantous A., Favrot C., Gibert B., Gadot N., Puisieux I., Herceg Z., Delcros J. G., Bernet A., Mehlen P., Dante R. (2016) Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference EMBO Mol Med; 8(8):863-77. PMID: 27378792

15. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

16. Ghantous A., Hernandez-Vargas H., Byrnes G., Dwyer T., Herceg Z. (2015) Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk Mutagenesis; 30(6):733-42. PMID: 25724893

17. Ancey P. B., Testoni B., Gruffaz M., Cros M. P., Durand G., Le Calvez-Kelm F., Durantel D., Herceg Z., Hernandez-Vargas H. (2015) Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes Oncotarget; . PMID: 26565721

18. Accardi R., Gruffat H., Sirand C., Fusil F., Gheit T., Hernandez-Vargas H., Le Calvez-Kelm F., Traverse-Glehen A., Cosset F. L., Manet E., Wild C. P., Tommasino M. (2015) The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models Carcinogenesis; 36(11):1440-51. PMID: 26424750

19. Torabi K., Miro R., Fernandez-Jimenez N., Quintanilla I., Ramos L., Prat E., Del Rey J., Pujol N., Killian J. K., Meltzer P. S., Fernandez P. L., Ried T., Lozano J. J., Camps J., Ponsa I. (2015) Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer Carcinogenesis; 36(10):1103-10. PMID: 26243311

20. Stronach E. A., Cunnea P., Turner C., Guney T., Aiyappa R., Jeyapalan S., de Sousa C. H., Browne A., Magdy N., Studd J. B., Sriraksa R., Gabra H., El-Bahrawy M. (2015) The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma Oncotarget; 6(31):31593-603. PMID: 26267317

21. Hernandez-Vargas H., Castelino J., Silver M. J., Dominguez-Salas P., Cros M. P., Durand G., Calvez-Kelm F. L., Prentice A. M., Wild C. P., Moore S. E., Hennig B. J., Herceg Z., Gong Y. Y., Routledge M. N. (2015) Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia Int J Epidemiol; 44(4):1238-48. PMID: 25855716

22. Taylor N. J., Reiner A. S., Begg C. B., Cust A. E., Busam K. J., Anton-Culver H., Dwyer T., From L., Gallagher R. P., Gruber S. B., Rosso S., White K. A., Zanetti R., Orlow I., Thomas N. E., Rebbeck T. R., Berwick M., Kanetsky P. A., G. E. M. Study Grp (2015) Inherited variation at MC1R and ASIP and association with melanoma-specific survival Int. J Cancer; 136(11):2659-2667. PMID: 25382380

23. Taylor N. J., Busam K. J., From L., Groben P. A., Anton-Culver H., Cust A. E., Begg C. B., Dwyer T., Gallagher R. P., Gruber S. B., Orlow I., Rosso S., Thomas N. E., Zanetti R., Rebbeck T. R., Berwick M., Kanetsky P. A. (2015) Inherited Variation at MC1R and Histological Characteristics of Primary Melanoma PLoS ONE; 10(3):10. PMID: 25790105

24. Wild C.P., Bucher J.R., de Jong B.W., Dillner J., von Gertten C., Groopman J.D., Herceg Z., Holmes E., Holmila R., Olsen J.H., Ringborg U., Scalbert A., Shibata T., Smith M.T., Ulrich C., Vineis P., McLaughlin J. (2015) Translational Cancer Research: Balancing Prevention and Treatment to Combat Cancer Globally J Natl Cancer Inst; 107(1):353. PMID: 25515230

25. Vaca-Paniagua F., Oliver J., Nogueira da Costa A., Merle P., McKay J., Herceg Z., Holmila R. (2015) Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing Epigenomics; 7(3):353-362. PMID: 26077425

26. Silver M.J., Kessler N.J., Hennig B.J., Dominguez-Salas P., Laritsky E., Baker M.S., Coarfa C., Hernandez-Vargas H., Castelino J.M., Routledge M.N., Gong Y.Y., Herceg Z., Lee Y.S., Lee K., Moore S.E., Fulford A.J., Prentice A.M., Waterland R.A. (2015) Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment Genome Biol; 16(1):118. PMID: 26062908

27. Sahay D., Leblanc R., Grunewald T.G., Ambatipudi S., Ribeiro J., Clezardin P., Peyruchaud O. (2015) The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer Oncotarget; 6(24):20604-20620. PMID: 26098771

28. Paltiel O., Tikellis G., Linet M., Golding J., Lemeshow S., Phillips G., Lamb K., Stoltenberg C., Haberg S.E., Strom M., Granstrom C., Northstone K., Klebanoff M., Ponsonby A.L., Milne E., Pedersen M., Kogevinas M., Ha E., Dwyer T. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C) Paediatr. Perinat. Epidemiol; 29(4):335-345. PMID: 25989709

29. Lee H. S. (2015) Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood Nutrients; 7(11):9492-507. PMID: 26593940

30. Lambert M.P., Ancey P.B., Esposti D.D., Cros M.P., Sklias A., Scoazec J.Y., Durantel D., Hernandez-Vargas H., Herceg Z. (2015) Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors Clin. Epigenetics; 7(1):15. PMID: 25755686

31. Kuasne H., Colus I.M., Busso A.F., Hernandez-Vargas H., Barros-Filho M.C., Marchi F.A., Scapulatempo-Neto C., Faria E.F., Lopes A., Guimaraes G.C., Herceg Z., Rogatto S.R. (2015) Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers Clin. Epigenetics; 7(1):46. PMID: 25908946

32. Kracker S., Di Virgilio M., Schwartzentruber J., Cuenin C., Forveille M., Deau M.C., McBride K.M., Majewski J., Gazumyan A., Seneviratne S., Grimbacher B., Kutukculer N., Herceg Z., Cavazzana M., Jabado N., Nussenzweig M.C., Fischer A., Durandy A. (2015) An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex J Allergy Clin. Immunol; 135(4):998-1007. PMID: 25312759

33. da Costa A.N., Plymoth A., Santos-Silva D., Ortiz-Cuaran S., Camey S., Guilloreau P., Sangrajrang S., Khuhaprema T., Mendy M., Lesi O.A., Chang H.K., Oh J.K., Lee D.H., Shin H.R., Kirk G.D., Merle P., Beretta L., Hainaut P. (2015) Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma Int J Cancer; 136(1):172-181. PMID: 24803312

34. Wang N., Tikellis G., Sun C., Pezic A., Wang L., Wells J.C., Cochrane J., Ponsonby A.L., Dwyer T. (2014) The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio Placenta; 35(7):437-441. PMID: 24816479

35. Thomas N.E., Kricker A., Waxweiler W.T., Dillon P.M., Busam K.J., From L., Groben P.A., Armstrong B.K., Anton-Culver H., Gruber S.B., Marrett L.D., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Orlow I., Paine S., Ollila D.W., Reiner A.S., Luo L., Hao H., Frank J.S., Begg C.B., Berwick M. (2014) Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas: A Population-Based Study JAMA Dermatol; 150(12):1306-1314. PMID: 25162299

36. Tapias A., Zhou Z.W., Shi Y., Chong Z., Wang P., Groth M., Platzer M., Huttner W., Herceg Z., Yang Y.G., Wang Z.Q. (2014) Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions Cell Stem Cell; 14(5):632-643. PMID: 24792116

37. Siouda M., Frecha C., Accardi R., Yue J., Cuenin C., Gruffat H., Manet E., Herceg Z., Sylla B.S., Tommasino M. (2014) Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression PLoS Pathog; 10(5):e1004125. PMID: 24809689

38. Ponsonby A.L., Dwyer T. (2014) Statistics: Biomedicine must look beyond P values Nature; 507(7491):169. PMID: 24622193

39. McCloskey K., Sun C., Pezic A., Cochrane J., Morley R., Vuillermin P., Burgner D., Dwyer T., Ponsonby A.L. (2014) The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study J Dev. Orig. Health Dis; 5(4):307-313. PMID: 24965137 http://jour

40. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC. Genomics; 435. PMID: 24898317

41. Lee H.S., Herceg Z. (2014) The epigenome and cancer prevention: A complex story of dietary supplementation Cancer Lett; 342(2):275-284. PMID: 22266189

42. Lee H.S., Barraza-Villarreal A., Biessy C., Duarte-Salles T., Sly P.D., Ramakrishnan U., Rivera J., Herceg Z., Romieu I. (2014) Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants Physiol Genomics; 46(23):851-857. PMID: 25293351

43. Leduc C., Chemin G., Puget N., Sawan C., Moutahir M., Herceg Z., Khamlichi A.A. (2014) Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells Cell Cycle; 13(10):1583-1589. PMID: 24675885

44. Ichim G., Mola M., Finkbeiner M.G., Cros M.P., Herceg Z., Hernandez-Vargas H. (2014) The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene; 33(2):181-192. PMID: 23318449

45. Herceg Z. (2014) Cancer prevention potential of diet and dietary supplements in epigenome modulation ; 43-70.

46. Hedley C., Sriraksa R., Showeil R., Van Noorden S., El-Bahrawy M. (2014) The frequency and significance of WT-1 expression in serous endometrial carcinoma Hum Pathol; 45(9):1879-1884. PMID: 25033726

47. Guillot C., Hall J., Herceg Z., Merle P., Chemin I. (2014) Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy Clin Res Hepatol. Gastroenterol; 38(2):137-142. PMID: 23953496

48. Guillot C., Favaudon V., Herceg Z., Sagne C., Sauvaigo S., Merle P., Hall J., Chemin I. (2014) PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models BMC. Cancer; 603. PMID: 25139788

49. Ghantous A., Saffery R., Cros M.P., Ponsonby A.L., Hirschfeld S., Kasten C., Dwyer T., Herceg Z., Hernandez-Vargas H. (2014) Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling BMC. Biotechnol; 60. PMID: 24980254

50. Ecsedi S., Hernandez-Vargas H., Lima S.C., Vizkeleti L., Toth R., Lazar V., Koroknai V., Kiss T., Emri G., Herceg Z., Adany R., Balazs M. (2014) DNA methylation characteristics of primary melanomas with distinct biological behaviour PLoS ONE; 9(5):e96612. PMID: 24832207

51. Durandy A, Kracker S., Schwartzentruber J., Cuenin C., Herceg Z., Jabado N., Nejentsev S, Fischer A. (2014) Immunoglobulin class-switch recombination deficiencies. Selected Abstracts from the 100th J Project Meeting, Antalya, Turkey, March 12-14, 2014 J Clin Immunol; 34(6):696.

52. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650. PMID: 24163401

53. Caygill C.P., Gatenby P.A., Herceg Z., Lima S.C., Pinto L.F., Watson A., Wu M.S. (2014) Comparative genomic analysis of esophageal cancers Ann N. Y. Acad Sci; 1325(1):69-76. PMID: 25266016

54. Berwick M., MacArthur J., Orlow I., Kanetsky P., Begg C.B., Luo L., Reiner A., Sharma A., Armstrong B.K., Kricker A., Cust A.E., Marrett L.D., Gruber S.B., Anton-Culver H., Zanetti R., Rosso S., Gallagher R.P., Dwyer T., Venn A., Busam K., From L., White K., Thomas N.E. (2014) MITF E318K's effect on melanoma risk independent of, but modified by, other risk factors Pigment Cell Melanoma Res; 27(3):485-488. PMID: 24406078

55. Wild C.P., Scalbert A., Herceg Z. (2013) Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk Environ. Mol. Mutagen; 54(7):480-499. PMID: 23681765

56. Umer M., Herceg Z. (2013) Deciphering the epigenetic code: an overview of DNA methylation analysis methods Antioxid. Redox. Signal; 18(15):1972-1986. PMID: 23121567

57. Thomas N.E., Busam K.J., From L., Kricker A., Armstrong B.K., Anton-Culver H., Gruber S.B., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Groben P.A., Hao H., Orlow I., Reiner A.S., Luo L., Paine S., Ollila D.W., Wilcox H., Begg C.B., Berwick M. (2013) Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study J Clin Oncol; 31(33):4252-4259. PMID: 24127443

58. Sawan C., Hernandez-Vargas H., Murr R., Lopez F., Vaissiere T., Ghantous A.Y., Cuenin C., Imbert J., Wang Z.Q., Ren B., Herceg Z. (2013) Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells Stem Cells; 31(5):979-991. PMID: 23362228 http://onli

59. Rakosy Z., Ecsedi S., Toth R., Vizkeleti L., Hernandez-Vargas H., Lazar V., Emri G., Szatmari I., Herceg Z., Adany R., Balazs M. (2013) Integrative genomics identifies gene signature associated with melanoma ulceration PLoS ONE; 8(1):e54958. PMID: 23383013

60. Ouzounova M., Vuong T., Ancey P.B., Ferrand M., Durand G., Le-Calvez Kelm F., Croce C., Matar C., Herceg Z., Hernandez-Vargas H. (2013) MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells BMC. Genomics; 139. PMID: 23445407

61. Lee H.S., Hernandez-Vargas H., Biessy C., Romieu I., Herceg Z., Barraza-Villarreal A., Sly P.D., Ramakrishnan U. (2013) Am. J Clin Nutr; 98(6):1595-1596. PMID: 24259359 http://ajcn

62. Lee H.S., Barraza-Villarreal A., Hernandez-Vargas H., Sly P.D., Biessy C., Ramakrishnan U., Romieu I., Herceg Z. (2013) Modulation of DNA methylation states and infant immune system by dietary supplementation with omega-3 PUFA during pregnancy in an intervention study Am. J Clin Nutr; 98(2):480-487. PMID: 23761484 https://www

63. Khoury M.J., Lam T.K., Ioannidis J.P., Hartge P., Spitz M.R., Buring J.E., Chanock S.J., Croyle R.T., Goddard K.A., Ginsburg G.S., Herceg Z., Hiatt R.A., Hoover R.N., Hunter D.J., Kramer B.S., Lauer M.S., Meyerhardt J.A., Olopade O.I., Palmer J.R., Sellers T.A., Seminara D., Ransohoff D.F., Rebbeck T.R., Tourassi G., Winn D.M., Zauber A., Schully S.D. (2013) Transforming epidemiology for 21st century medicine and public health Cancer Epidemiol Biomarkers Prev; 22(4):508-516. PMID: 23462917

64. Herceg Z., Lambert M.P., van Veldhoven K., Demetriou C., Vineis P., Smith M.T., Straif K., Wild C.P. (2013) Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation Carcinogenesis; 34(9):1955-1967. PMID: 23749751

65. Gospodinov A., Herceg Z. (2013) Chromatin structure in double strand break repair DNA Repair (Amst); 12(10):800-810. PMID: 23919923

66. Gospodinov A., Herceg Z. (2013) Shaping chromatin for repair Mutat Res; 752(1):45-60. PMID: 23085398

67. Ghantous A., Sinjab A., Herceg Z., Darwiche N. (2013) Parthenolide: from plant shoots to cancer roots Drug Discov. Today; 18(17):894-905. PMID: 23688583

68. Genevois A.L., Ichim G., Coissieux M.M., Lambert M.P., Lavial F., Goldschneider D., Jarrosson-Wuilleme L., Lepinasse F., Gouysse G., Herceg Z., Scoazec J.Y., Tauszig-Delamasure S., Mehlen P. (2013) Dependence receptor TrkC is a putative colon cancer tumor suppressor Proc Natl Acad Sci U S A; 110(8):3017-3022. PMID: 23341610

69. El Hajj H., Ali J., Ghantous A., Hodroj D., Daher A., Zibara K., Journo C., Otrock Z., Zaatari G., Mahieux R., El Sabban M., Bazarbachi A., Abou Merhi R. (2013) Combination of arsenic and interferon-alpha inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas PLoS ONE; 8(11):e79474. PMID: 24250827 https://www

70. Ecsedi S.I., Hernandez-Vargas H., Lima S.C., Herceg Z., Adany R., Balazs M. (2013) Transposable hypomethylation is associated with metastatic capacity of primary melanomas Int. J Clin Exp. Pathol; 6(12):2943-2948. PMID: 24294382

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