Research Groups

Mechanisms of Carcinogenesis - Epigenetics Group

Previous Publications - All publications 2018-2014

1. Ghantous A., Hernandez-Vargas H., Herceg Z. (2018) DNA Methylation Analysis from Blood Spots: Increasing Yield and Quality for Genome-Wide and Locus-Specific Methylation Analysis Methods Mol Biol; 605-619. PMID: 29224166

2. Bisarro Dos Reis M., Barros-Filho M. C., Marchi F. A., Beltrami C. M., Kuasne H., Pinto C. A. L., Ambatipudi S., Herceg Z., Kowalski L. P., Rogatto S. R. (2017) Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors J Clin Endocrinol Metab; 102(11):4089-4099. PMID: 28938489

3. Degli Esposti D., Aushev V. N., Lee E., Cros M. P., Zhu J., Herceg Z., Chen J., Hernandez-Vargas H. (2017) miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival Sci Rep; 7(1):15966. PMID: 29162888

4. Kettunen E., Hernandez-Vargas H., Cros M. P., Durand G., Le Calvez-Kelm F., Stuopelyte K., Jarmalaite S., Salmenkivi K., Anttila S., Wolff H., Herceg Z., Husgafvel-Pursiainen K. (2017) Asbestos-associated genome-wide DNA methylation changes in lung cancer Int J Cancer; 141(10):2014-2029. PMID: 28722770

5. Huskova H., Ardin M., Weninger A., Vargova K., Barrin S., Villar S., Olivier M., Stopka T., Herceg Z., Hollstein M., Zavadil J., Korenjak M. (2017) Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing Oncogene; 36(43):6041-6048. PMID: 28692054

6. Mathot P., Grandin M., Devailly G., Souaze F., Cahais V., Moran S., Campone M., Herceg Z., Esteller M., Juin P., Mehlen P., Dante R. (2017) DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment Oncogenesis; 6(10):e390. PMID: 29058695

7. Sharp G. C., Salas L. A., Monnereau C., Allard C., Yousefi P., Everson T. M., Bohlin J., Xu Z., Huang R. C., Reese S. E., Xu C. J., Baiz N., Hoyo C., Agha G., Roy R., Holloway J. W., Ghantous A., Merid S. K., Bakulski K. M., Kupers L. K., Zhang H., Richmond R. C., Page C. M., Duijts L., Lie R. T., Melton P. E., Vonk J. M., Nohr E. A., Williams-DeVane C., Huen K., Rifas-Shiman S. L., Ruiz-Arenas C., Gonseth S., Rezwan F. I., Herceg Z., Ekstrom S., Croen L., Falahi F., Perron P., Karagas M. R., Quraishi B. M., Suderman M., Magnus M. C., Jaddoe V. W. V., Taylor J. A., Anderson D., Zhao S., Smit H. A., Josey M. J., Bradman A., Baccarelli A. A., Bustamante M., Haberg S. E., Pershagen G., Hertz-Picciotto I., Newschaffer C., Corpeleijn E., Bouchard L., Lawlor D. A., Maguire R. L., Barcellos L. F., Davey Smith G., Eskenazi B., Karmaus W., Marsit C. J., Hivert M. F., Snieder H., Fallin M. D., Melen E., Munthe-Kaas M. C., Arshad H., Wiemels J. L., Annesi-Maesano I., Vrijheid M., Oken E., Holland N., Murphy S. K., Sorensen T. I. A., Koppelman G. H., Newnham J. P., Wilcox A. J., Nystad W., London S. J., Felix J. F., Relton C. L. (2017) Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium Hum Mol Genet; 26(20):4067-4085. PMID: 29016858

8. Narvaez D. M., Groot H., Diaz S. M., Palma R. M., Munoz N., Cros M. P., Hernandez-Vargas H. (2017) Oxidative stress and repetitive element methylation changes in artisanal gold miners occupationally exposed to mercury Heliyon; 3(9):e00400. PMID: 28948237

9. Ancey P. B., Ecsedi S., Lambert M. P., Talukdar F. R., Cros M. P., Glaise D., Narvaez D. M., Chauvet V., Herceg Z., Corlu A., Hernandez-Vargas H. (2017) TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors Stem Cell Reports; 9(1):264-278. PMID: 28648900

10. Col E., Hoghoughi N., Dufour S., Penin J., Koskas S., Faure V., Ouzounova M., Hernandez-Vargash H., Reynoird N., Daujat S., Folco E., Vigneron M., Schneider R., Verdel A., Khochbin S., Herceg Z., Caron C., Vourc\'h C. (2017) Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock Sci Rep; 7(1):5418. PMID: 28710461

11. Hernandez-Vargas H., Gruffat H., Cros M. P., Diederichs A., Sirand C., Vargas-Ayala R. C., Jay A., Durand G., Le Calvez-Kelm F., Herceg Z., Manet E., Wild C. P., Tommasino M., Accardi R. (2017) Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines Sci Rep; 7(1):5852. PMID: 28724958

12. Ambatipudi S., Horvath S., Perrier F., Cuenin C., Hernandez-Vargas H., Le Calvez-Kelm F., Durand G., Byrnes G., Ferrari P., Bouaoun L., Sklias A., Chajes V., Overvad K., Severi G., Baglietto L., Clavel-Chapelon F., Kaaks R., Barrdahl M., Boeing H., Trichopoulou A., Lagiou P., Naska A., Masala G., Agnoli C., Polidoro S., Tumino R., Panico S., Dolle M., Peeters P. H., Onland-Moret N. C., Sandanger T. M., Nost T. H., Weiderpass E., Quiros J. R., Agudo A., Rodriguez-Barranco M., Huerta Castano J. M., Barricarte A., Fernandez A. M., Travis R. C., Vineis P., Muller D. C., Riboli E., Gunter M., Romieu I., Herceg Z. (2017) DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility Eur J Cancer; 299-307. PMID: 28259012

13. Degli Esposti D., Sklias A., Lima S. C., Beghelli-de la Forest Divonne S., Cahais V., Fernandez-Jimenez N., Cros M. P., Ecsedi S., Cuenin C., Bouaoun L., Byrnes G., Accardi R., Sudaka A., Giordanengo V., Hernandez-Vargas H., Pinto L. F., Van Obberghen-Schilling E., Herceg Z. (2017) Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas Genome Med; 9(1):33. PMID: 28381277

14. Vineis P., Chadeau-Hyam M., Gmuender H., Gulliver J., Herceg Z., Kleinjans J., Kogevinas M., Kyrtopoulos S., Nieuwenhuijsen M., Phillips D. H., Probst-Hensch N., Scalbert A., Vermeulen R., Wild C. P. (2017) The exposome in practice: Design of the EXPOsOMICS project Int J Hyg Environ Health; 220(2):142-151. PMID: 27576363

15. Beltrami C. M., Dos Reis M. B., Barros-Filho M. C., Marchi F. A., Kuasne H., Pinto C. A. L., Ambatipudi S., Herceg Z., Kowalski L. P., Rogatto S. R. (2017) Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas Clin Epigenetics; 45. PMID: 28469731

16. Fernandez-Jimenez N., Sklias A., Ecsedi S., Cahais V., Degli-Esposti D., Jay A., Ancey P. B., Woo H. D., Hernandez-Vargas H., Herceg Z. (2017) Lowly methylated region analysis identifies EBF1 as a potential epigenetic modifier in breast cancer Epigenetics; 12(11):964-972. PMID: 29099283

17. Gonzaga I. M., Soares Lima S. C., Nicolau M. C., Nicolau-Neto P., da Costa N. M., de Almeida Simao T., Hernandez-Vargas H., Herceg Z., Ribeiro Pinto L. F. (2017) TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells Clin Epigenetics; 130. PMID: 29296124

18. Halaburkova A., Jendzelovsky R., Koval J., Herceg Z., Fedorocko P., Ghantous A. (2017) Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A Clin Epigenetics; 62. PMID: 28603560

19. Holmila R., Sklias A., Muller D. C., Degli Esposti D., Guilloreau P., McKay J., Sangrajrang S., Srivatanakul P., Hainaut P., Merle P., Herceg Z., Nogueira da Costa A. (2017) Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma PLoS ONE; 12(3):e0174265. PMID: 28333958

20. Lee Ho-Sun, Herceg Zdenko (2017) Chapter 30 – Nutritional Epigenome and Metabolic Syndrome ; 465?475.

21. Vanzan Ludovica, Sklias Athena, Herceg Zdenko (2017) Chapter 3 – Mechanisms of Histone Modifications ; 25?46.

22. Joehanes R., Just A. C., Marioni R. E., Pilling L. C., Reynolds L. M., Mandaviya P. R., Guan W., Xu T., Elks C. E., Aslibekyan S., Moreno-Macias H., Smith J. A., Brody J. A., Dhingra R., Yousefi P., Pankow J. S., Kunze S., Shah S. H., McRae A. F., Lohman K., Sha J., Absher D. M., Ferrucci L., Zhao W., Demerath E. W., Bressler J., Grove M. L., Huan T., Liu C., Mendelson M. M., Yao C., Kiel D. P., Peters A., Wang-Sattler R., Visscher P. M., Wray N. R., Starr J. M., Ding J., Rodriguez C. J., Wareham N. J., Irvin M. R., Zhi D., Barrdahl M., Vineis P., Ambatipudi S., Uitterlinden A. G., Hofman A., Schwartz J., Colicino E., Hou L., Vokonas P. S., Hernandez D. G., Singleton A. B., Bandinelli S., Turner S. T., Ware E. B., Smith A. K., Klengel T., Binder E. B., Psaty B. M., Taylor K. D., Gharib S. A., Swenson B. R., Liang L., DeMeo D. L., O\'Connor G. T., Herceg Z., Ressler K. J., Conneely K. N., Sotoodehnia N., Kardia S. L., Melzer D., Baccarelli A. A., van Meurs J. B., Romieu I., Arnett D. K., Ong K. K., Liu Y., Waldenberger M., Deary I. J., Fornage M., Levy D., London S. J. (2016) Epigenetic Signatures of Cigarette Smoking Circ Cardiovasc Genet; 9(5):436-447. PMID: 27651444

23. Ambatipudi S., Cuenin C., Hernandez-Vargas H., Ghantous A., Le Calvez-Kelm F., Kaaks R., Barrdahl M., Boeing H., Aleksandrova K., Trichopoulou A., Lagiou P., Naska A., Palli D., Krogh V., Polidoro S., Tumino R., Panico S., Bueno-de-Mesquita B., Peeters P. H., Quiros J. R., Navarro C., Ardanaz E., Dorronsoro M., Key T., Vineis P., Murphy N., Riboli E., Romieu I., Herceg Z. (2016) Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study Epigenomics; 8(5):599-618. PMID: 26864933

24. Esposti D. D., Hernandez-Vargas H., Voegele C., Fernandez-Jimenez N., Forey N., Bancel B., Le Calvez-Kelm F., McKay J., Merle P., Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing Oncotarget; 7(22):31862-77. PMID: 26887054

25. Joubert B. R., Felix J. F., Yousefi P., Bakulski K. M., Just A. C., Breton C., Reese S. E., Markunas C. A., Richmond R. C., Xu C. J., Kupers L. K., Oh S. S., Hoyo C., Gruzieva O., Soderhall C., Salas L. A., Baiz N., Zhang H., Lepeule J., Ruiz C., Ligthart S., Wang T., Taylor J. A., Duijts L., Sharp G. C., Jankipersadsing S. A., Nilsen R. M., Vaez A., Fallin M. D., Hu D., Litonjua A. A., Fuemmeler B. F., Huen K., Kere J., Kull I., Munthe-Kaas M. C., Gehring U., Bustamante M., Saurel-Coubizolles M. J., Quraishi B. M., Ren J., Tost J., Gonzalez J. R., Peters M. J., Haberg S. E., Xu Z., van Meurs J. B., Gaunt T. R., Kerkhof M., Corpeleijn E., Feinberg A. P., Eng C., Baccarelli A. A., Benjamin Neelon S. E., Bradman A., Merid S. K., Bergstrom A., Herceg Z., Hernandez-Vargas H., Brunekreef B., Pinart M., Heude B., Ewart S., Yao J., Lemonnier N., Franco O. H., Wu M. C., Hofman A., McArdle W., Van der Vlies P., Falahi F., Gillman M. W., Barcellos L. F., Kumar A., Wickman M., Guerra S., Charles M. A., Holloway J., Auffray C., Tiemeier H. W., Smith G. D., Postma D., Hivert M. F., Eskenazi B., Vrijheid M., Arshad H., Anto J. M., Dehghan A., Karmaus W., Annesi-Maesano I., Sunyer J., Ghantous A., Pershagen G., Holland N., Murphy S. K., DeMeo D. L., Burchard E. G., Ladd-Acosta C., Snieder H., Nystad W., Koppelman G. H., Relton C. L., Jaddoe V. W., Wilcox A., Melen E., London S. J. (2016) DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis Am J Hum Genet; 98(4):680-96. PMID: 27040690

26. Showeil R., Romano C., Valganon M., Lambros M., Trivedi P., Van Noorden S., Sriraksa R., El-Kaffash D., El-Etreby N., Natrajan R., Foroni L., Osborne R., El-Bahrawy M. (2016) The status of epidermal growth factor receptor in borderline ovarian tumours Oncotarget; 7(9):10568-77. PMID: 26870997

27. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

28. Grandin M., Mathot P., Devailly G., Bidet Y., Ghantous A., Favrot C., Gibert B., Gadot N., Puisieux I., Herceg Z., Delcros J. G., Bernet A., Mehlen P., Dante R. (2016) Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference EMBO Mol Med; 8(8):863-77. PMID: 27378792

29. Herceg Z. (2016) Epigenetic Mechanisms as an Interface Between the Environment and Genome Adv Exp Med Biol; 3-15. PMID: 27343085

30. Vuong T., Mallet J. F., Ouzounova M., Rahbar S., Hernandez-Vargas H., Herceg Z., Matar C. (2016) Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation J Transl Med; 14(13):1-12. PMID: 26762586

31. Accardi R., Gruffat H., Sirand C., Fusil F., Gheit T., Hernandez-Vargas H., Le Calvez-Kelm F., Traverse-Glehen A., Cosset F. L., Manet E., Wild C. P., Tommasino M. (2015) The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models Carcinogenesis; 36(11):1440-51. PMID: 26424750

32. Ancey P. B., Testoni B., Gruffaz M., Cros M. P., Durand G., Le Calvez-Kelm F., Durantel D., Herceg Z., Hernandez-Vargas H. (2015) Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes Oncotarget; . PMID: 26565721

33. Ghantous A., Hernandez-Vargas H., Byrnes G., Dwyer T., Herceg Z. (2015) Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk Mutagenesis; 30(6):733-42. PMID: 25724893

34. Stronach E. A., Cunnea P., Turner C., Guney T., Aiyappa R., Jeyapalan S., de Sousa C. H., Browne A., Magdy N., Studd J. B., Sriraksa R., Gabra H., El-Bahrawy M. (2015) The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma Oncotarget; 6(31):31593-603. PMID: 26267317

35. Torabi K., Miro R., Fernandez-Jimenez N., Quintanilla I., Ramos L., Prat E., Del Rey J., Pujol N., Killian J. K., Meltzer P. S., Fernandez P. L., Ried T., Lozano J. J., Camps J., Ponsa I. (2015) Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer Carcinogenesis; 36(10):1103-10. PMID: 26243311

36. Hernandez-Vargas H., Castelino J., Silver M. J., Dominguez-Salas P., Cros M. P., Durand G., Calvez-Kelm F. L., Prentice A. M., Wild C. P., Moore S. E., Hennig B. J., Herceg Z., Gong Y. Y., Routledge M. N. (2015) Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia Int J Epidemiol; 44(4):1238-48. PMID: 25855716

37. Taylor N. J., Reiner A. S., Begg C. B., Cust A. E., Busam K. J., Anton-Culver H., Dwyer T., From L., Gallagher R. P., Gruber S. B., Rosso S., White K. A., Zanetti R., Orlow I., Thomas N. E., Rebbeck T. R., Berwick M., Kanetsky P. A., G. E. M. Study Grp (2015) Inherited variation at MC1R and ASIP and association with melanoma-specific survival Int. J Cancer; 136(11):2659-2667. PMID: 25382380

38. Taylor N. J., Busam K. J., From L., Groben P. A., Anton-Culver H., Cust A. E., Begg C. B., Dwyer T., Gallagher R. P., Gruber S. B., Orlow I., Rosso S., Thomas N. E., Zanetti R., Rebbeck T. R., Berwick M., Kanetsky P. A. (2015) Inherited Variation at MC1R and Histological Characteristics of Primary Melanoma PLoS ONE; 10(3):10. PMID: 25790105

39. da Costa A.N., Plymoth A., Santos-Silva D., Ortiz-Cuaran S., Camey S., Guilloreau P., Sangrajrang S., Khuhaprema T., Mendy M., Lesi O.A., Chang H.K., Oh J.K., Lee D.H., Shin H.R., Kirk G.D., Merle P., Beretta L., Hainaut P. (2015) Osteopontin and latent-TGF beta binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma Int J Cancer; 136(1):172-181. PMID: 24803312

40. Kracker S., Di Virgilio M., Schwartzentruber J., Cuenin C., Forveille M., Deau M.C., McBride K.M., Majewski J., Gazumyan A., Seneviratne S., Grimbacher B., Kutukculer N., Herceg Z., Cavazzana M., Jabado N., Nussenzweig M.C., Fischer A., Durandy A. (2015) An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex J Allergy Clin. Immunol; 135(4):998-1007. PMID: 25312759

41. Kuasne H., Colus I.M., Busso A.F., Hernandez-Vargas H., Barros-Filho M.C., Marchi F.A., Scapulatempo-Neto C., Faria E.F., Lopes A., Guimaraes G.C., Herceg Z., Rogatto S.R. (2015) Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers Clin. Epigenetics; 7(1):46. PMID: 25908946

42. Lambert M.P., Ancey P.B., Esposti D.D., Cros M.P., Sklias A., Scoazec J.Y., Durantel D., Hernandez-Vargas H., Herceg Z. (2015) Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors Clin. Epigenetics; 7(1):15. PMID: 25755686

43. Lee H. S. (2015) Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood Nutrients; 7(11):9492-507. PMID: 26593940

44. Paltiel O., Tikellis G., Linet M., Golding J., Lemeshow S., Phillips G., Lamb K., Stoltenberg C., Haberg S.E., Strom M., Granstrom C., Northstone K., Klebanoff M., Ponsonby A.L., Milne E., Pedersen M., Kogevinas M., Ha E., Dwyer T. (2015) Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C) Paediatr. Perinat. Epidemiol; 29(4):335-345. PMID: 25989709

45. Sahay D., Leblanc R., Grunewald T.G., Ambatipudi S., Ribeiro J., Clezardin P., Peyruchaud O. (2015) The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer Oncotarget; 6(24):20604-20620. PMID: 26098771

46. Silver M.J., Kessler N.J., Hennig B.J., Dominguez-Salas P., Laritsky E., Baker M.S., Coarfa C., Hernandez-Vargas H., Castelino J.M., Routledge M.N., Gong Y.Y., Herceg Z., Lee Y.S., Lee K., Moore S.E., Fulford A.J., Prentice A.M., Waterland R.A. (2015) Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment Genome Biol; 16(1):118. PMID: 26062908

47. Vaca-Paniagua F., Oliver J., Nogueira da Costa A., Merle P., McKay J., Herceg Z., Holmila R. (2015) Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing Epigenomics; 7(3):353-362. PMID: 26077425

48. Wild C.P., Bucher J.R., de Jong B.W., Dillner J., von Gertten C., Groopman J.D., Herceg Z., Holmes E., Holmila R., Olsen J.H., Ringborg U., Scalbert A., Shibata T., Smith M.T., Ulrich C., Vineis P., McLaughlin J. (2015) Translational Cancer Research: Balancing Prevention and Treatment to Combat Cancer Globally J Natl Cancer Inst; 107(1):353. PMID: 25515230

49. Berwick M., MacArthur J., Orlow I., Kanetsky P., Begg C.B., Luo L., Reiner A., Sharma A., Armstrong B.K., Kricker A., Cust A.E., Marrett L.D., Gruber S.B., Anton-Culver H., Zanetti R., Rosso S., Gallagher R.P., Dwyer T., Venn A., Busam K., From L., White K., Thomas N.E. (2014) MITF E318K\'s effect on melanoma risk independent of, but modified by, other risk factors Pigment Cell Melanoma Res; 27(3):485-488. PMID: 24406078

50. Caygill C.P., Gatenby P.A., Herceg Z., Lima S.C., Pinto L.F., Watson A., Wu M.S. (2014) Comparative genomic analysis of esophageal cancers Ann N. Y. Acad Sci; 1325(1):69-76. PMID: 25266016

51. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650. PMID: 24163401

52. Durandy A, Kracker S., Schwartzentruber J., Cuenin C., Herceg Z., Jabado N., Nejentsev S, Fischer A. (2014) Immunoglobulin class-switch recombination deficiencies. Selected Abstracts from the 100th J Project Meeting, Antalya, Turkey, March 12-14, 2014 J Clin Immunol; 34(6):696.

53. Ecsedi S., Hernandez-Vargas H., Lima S.C., Vizkeleti L., Toth R., Lazar V., Koroknai V., Kiss T., Emri G., Herceg Z., Adany R., Balazs M. (2014) DNA methylation characteristics of primary melanomas with distinct biological behaviour PLoS ONE; 9(5):e96612. PMID: 24832207

54. Ghantous A., Saffery R., Cros M.P., Ponsonby A.L., Hirschfeld S., Kasten C., Dwyer T., Herceg Z., Hernandez-Vargas H. (2014) Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling BMC. Biotechnol; 60. PMID: 24980254

55. Guillot C., Favaudon V., Herceg Z., Sagne C., Sauvaigo S., Merle P., Hall J., Chemin I. (2014) PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models BMC. Cancer; 603. PMID: 25139788

56. Guillot C., Hall J., Herceg Z., Merle P., Chemin I. (2014) Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy Clin Res Hepatol. Gastroenterol; 38(2):137-142. PMID: 23953496

57. Hedley C., Sriraksa R., Showeil R., Van Noorden S., El-Bahrawy M. (2014) The frequency and significance of WT-1 expression in serous endometrial carcinoma Hum Pathol; 45(9):1879-1884. PMID: 25033726

58. Herceg Z. (2014) Cancer prevention potential of diet and dietary supplements in epigenome modulation ; 43-70.

59. Ichim G., Mola M., Finkbeiner M.G., Cros M.P., Herceg Z., Hernandez-Vargas H. (2014) The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle Oncogene; 33(2):181-192. PMID: 23318449

60. Leduc C., Chemin G., Puget N., Sawan C., Moutahir M., Herceg Z., Khamlichi A.A. (2014) Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells Cell Cycle; 13(10):1583-1589. PMID: 24675885

61. Lee H.S., Barraza-Villarreal A., Biessy C., Duarte-Salles T., Sly P.D., Ramakrishnan U., Rivera J., Herceg Z., Romieu I. (2014) Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants Physiol Genomics; 46(23):851-857. PMID: 25293351

62. Lee H.S., Herceg Z. (2014) The epigenome and cancer prevention: A complex story of dietary supplementation Cancer Lett; 342(2):275-284. PMID: 22266189

63. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC. Genomics; 435. PMID: 24898317

64. McCloskey K., Sun C., Pezic A., Cochrane J., Morley R., Vuillermin P., Burgner D., Dwyer T., Ponsonby A.L. (2014) The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study J Dev. Orig. Health Dis; 5(4):307-313. PMID: 24965137

65. Ponsonby A.L., Dwyer T. (2014) Statistics: Biomedicine must look beyond P values Nature; 507(7491):169. PMID: 24622193

66. Siouda M., Frecha C., Accardi R., Yue J., Cuenin C., Gruffat H., Manet E., Herceg Z., Sylla B.S., Tommasino M. (2014) Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression PLoS Pathog; 10(5):e1004125. PMID: 24809689

67. Tapias A., Zhou Z.W., Shi Y., Chong Z., Wang P., Groth M., Platzer M., Huttner W., Herceg Z., Yang Y.G., Wang Z.Q. (2014) Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions Cell Stem Cell; 14(5):632-643. PMID: 24792116

68. Thomas N.E., Kricker A., Waxweiler W.T., Dillon P.M., Busam K.J., From L., Groben P.A., Armstrong B.K., Anton-Culver H., Gruber S.B., Marrett L.D., Gallagher R.P., Zanetti R., Rosso S., Dwyer T., Venn A., Kanetsky P.A., Orlow I., Paine S., Ollila D.W., Reiner A.S., Luo L., Hao H., Frank J.S., Begg C.B., Berwick M. (2014) Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas: A Population-Based Study JAMA Dermatol; 150(12):1306-1314. PMID: 25162299

69. Wang N., Tikellis G., Sun C., Pezic A., Wang L., Wells J.C., Cochrane J., Ponsonby A.L., Dwyer T. (2014) The effect of maternal prenatal smoking and alcohol consumption on the placenta-to-birth weight ratio Placenta; 35(7):437-441. PMID: 24816479