Research Groups

Section of Environment and Radiation

Current Research Topics:

Environmental and occupational exposures
  • AGRICOH research consortium: Pooled analyses of data from 26 cohort studies of agricultural workers or pesticide applicators and their families, to investigate cancer risk and that of other diseases related to exposure to pesticides and other prevalent agricultural exposures (http://agricoh.iarc.fr); specific ongoing projects include i) overall cancer risks in various agricultural activities, ii) risk of haematological malignancies in farmers (pooled study including France, Norway, and the USA)
  • Case-control study on causes of testicular cancer in France (TESTESPERA), with a focus on endocrine-disrupting agents (including pesticides); register-based case-control study in the Nordic countries on testicular cancer and parental occupational exposures in particular in regard to exposure to pesticides (NORDTEST)
  • Parental occupational and home exposure to pesticides and the risk of childhood cancer, using two pooling approaches: i) case-control studies from the Childhood Leukemia International Consortium (CLIC); ii) Mother and child cohort studies from the International Childhood Cancer Cohort Consortium (I4C)
  • SYNERGY research consortium: Studying lung cancer risk following combined occupational exposures and smoking, by pooling case-control studies of lung cancer from 13 countries (http://synergy.iarc.fr); selected carcinogens in main analyses include asbestos, respirable crystalline silica, polycyclic aromatic hydrocarbons (PAH), chromium and nickel
  • Occupational exposure to loud noise and the risk of vestibular schwannoma (acoustic neuroma); pooled analyses of case-control studies
  • Pooling project of European cohort studies of workers employed in the contemporary rubber industry
  • Occupational exposure to chrysotile in workers in mines and processing facilities in Asbest, Russian Federation (cohort study) (http://asbest-study.iarc.fr)
  • Estimating the asbestos-related lung cancer mortality burden from mesothelioma deaths.

Lifestyle factors
  • Pilot case-control study of lifestyle factors, including qat chewing and tobacco use and upper digestive tract cancer in Ethiopia
  • Smoking patterns in first and second generation immigrants in France (cross-sectional study)
  • Lung cancer risk in first and second generation immigrants in Denmark (nationwide cohort study)
  • Publication of the IARC Handbooks of Cancer Prevention, Tobacco Control:
    - Volume 11 Reversal of Risk after Quitting Smoking
    - Volume 12 Methods for Evaluating Tobacco Control Policies
    - Volume 13 Evaluating the effectiveness of smoke-free policies
    - Volume 14 Effectiveness of Tax and Price Policies for Tobacco Control, within the EC-FP7
    funded PPACTE project (www.ppacte.eu)
  • Update of the European Code against Cancer (4th revision; coordination together with IARC Quality Assurance Group).

Ionizing radiation
  • Multinational cohort study (coordination), EPI-CT: Cohort studies of children with CT examination and follow up for childhood cancer
  • Follow-up to the International Study of Workers in the Nuclear Industry (extended follow up of cohorts in France, the UK, and the USA)
  • Compilation of historical breast doses from X-ray diagnosis
  • Evaluation of the health effects of the Chernobyl accident: a) Agenda for Research on Chernobyl Health (ARCH): to develop a strategic plan for research on the health consequences of radiation for the Chernobyl accident; b) Case-control studies of haematological malignancies and of thyroid cancer among Chernobyl emergency accident workers in Belarus, the Russian Federation and the Baltic states
  • Genetic and environmental factors in cancer: Case-control study of thyroid cancer in young people in the wake of the Chernobyl accident
  • GENE-RAD-RISK: Radiation exposures at an early age: impact of genotype on breast cancer risk
  • Radiation-related disease risk in nuclear facility workers and their offspring and local residents and their offspring: pooled analyses of cancer risk in persons with in-utero exposure to ionizing radiation of exposed population in the Southern Urals, Russia (SOLO project)
  • Assessment of feasibility of setting up a prospective integrated epidemiologic study of cancer risk in residents near the Semipalatinsk nuclear test site in Kazakhstan.

Non-ionizing radiation
  • Multinational case-control study INTERPHONE: Large multicentric study of tumours of the brain, acoustic nerve and parotid gland in relation with radiofrequency radiation emitted by mobile telephones (The Interphone Study)
  • Participation in cohort studies of mobile phone users: i) Danish nationwide cohort of early (1982-1995) mobile phone subscribers; ii) multinational prospective cohort study of mobile phone users in Denmark, Finland, Sweden, The Netherlands, and the UK (Cosmos study); conduct of pilot study in France to join the Cosmos study
  • Participation in the CEFALO multinational case-control study: Multicentric study of brain tumours in children and adolescents in relation to mobile phone use
  • Pooled analyses of studies on exposure to extremely low-frequency magnetic fields and survival of childhood leukaemia.

Cancer-specific investigations
  • Breast cancer:
    - International Pooling Project of Mammographic Density (http://mdpool.iarc.fr)
    - African Breast Cancer-Disparities in Outcomes study (ABC-DO): an African multi-country study of the entire journey of a breast cancer patient, to identify determinants and pathways of poor survival (http://abc-do.iarc.fr/)
    - Breast Cancer in Southern Africa: Population-based review of hormone receptor status performed at diagnosis across Southern Africa
  • Oesophageal cancer:
    - studies in high-incidence areas, particularly Eastern Africa (pilot studies in Kenya, Tanzania, South Africa)
  • Brain tumours:
    - risk factors such as medical conditions (particularly allergies), family history of cancer, smoking, diagnostic ionizing radiation, and occupational exposures using pooling of case-control studies from Interphone
    - time trends in brain tumour incidence rates
  • Childhood cancers:
    - risk factors for brain tumours in teenagers and adolescents such as social contacts, infections, animal contacts, allergies, birth characteristics, and maternal exposures during pregnancy, using pooled case-control studies (Cefalo study)
    - birth characteristics and risk of solid tumours in children, using record linkage-based case-control studies in the Nordic countries
    - determinants of survival of childhood cancer, using cohorts from the UK and Germany, and extending to pool case-series from studies from the CLIC
    - pilot study on assessing characteristics of childhood leukaemia from high and low incidence areas around the world (galnet.iarc.fr)