Research Groups

Section of Genetics - Genetic Cancer Susceptibility Group

Recent Publications - 12 most recent publications

1. Couraud S., Vaca-Paniagua F., Villar S., Oliver J., Schuster T., Blanche H., Girard N., Tredaniel J., Guilleminault L., Gervais R., Prim N., Vincent M., Margery J., Larive S., Foucher P., Duvert B., Vallee M., Le Calvez-Kelm F., McKay J., Missy P., Morin F., Zalcman G., Olivier M., Souquet P.J. (2014) Noninvasive Diagnosis of Actionable Mutations by Deep Sequencing of Circulating Free DNA in Lung Cancer from Never-Smokers: A Proof-of-Concept Study from BioCAST/IFCT-1002 Clinical cancer research; 20(17):4613-4624. PMID: 25013125

2. Kim Y.H., Ohta T., Oh J.E., Le Calvez-Kelm F., McKay J., Voegele C., Durand G., Mittelbronn M., Kleihues P., Paulus W., Ohgaki H. (2014) TP53, MSH4, and LATS1 Germline Mutations in a Family with Clustering of Nervous System Tumors American journal of pathology; 184(9):2374-2381. PMID: 25041856

3. Babron M.C., Kazma R., Gaborieau V., McKay J., Brennan P., Sarasin A., Benhamou S. (2014) Genetic variants in DNA repair pathways and risk of upper aerodigestive tract cancers: combined analysis of data from two genome-wide association studies in European populations Carcinogenesis; 35(7):1523-1527. PMID: 24658182

4. Park D.J., Tao K., Le Calvez-Kelm F., Nguyen-Dumont T., Robinot N., Hammet F., Odefrey F., Tsimiklis H., Teo Z.L., Thingholm L.B., Young E.L., Voegele C., Lonie A., Pope B.J., Roane T.C., Bell R., Hu H., Shankaracharya, Huff C.D., Ellis J., Li J., Makunin I.V., John E.M., Andrulis I.L., Terry M.B., Daly M., Buys S.S., Snyder C., Lynch H.T., Devilee P., Giles G.G., Hopper J.L., Feng B.J., Lesueur F., Tavtigian S.V., Southey M.C., Goldgar D.E. (2014) Rare Mutations in RINT1 Predispose Carriers to Breast and Lynch Syndrome-Spectrum Cancers Cancer Discov.; 4(7):804-815. PMID: 25050558

5. Wang Y., McKay J.D., Rafnar T., Wang Z., Timofeeva M.N., Broderick P., Zong X., Laplana M., Wei Y., Han Y., Lloyd A., Delahaye-Sourdeix M., Chubb D., Gaborieau V., Wheeler W., Chatterjee N., Thorleifsson G., Sulem P., Liu G., Kaaks R., Henrion M., Kinnersley B., Vallee M., LeCalvez-Kelm F., Stevens V.L., Gapstur S.M., Chen W.V., Zaridze D., Szeszenia-Dabrowska N., Lissowska J., Rudnai P., Fabianova E., Mates D., Bencko V., Foretova L., Janout V., Krokan H.E., Gabrielsen M.E., Skorpen F., Vatten L., Njolstad I., Chen C., Goodman G., Benhamou S., Vooder T., Valk K., Nelis M., Metspalu A., Lener M., Lubinski J., Johansson M., Vineis P., Agudo A., Clavel-Chapelon F., Bueno-de-Mesquita H.B., Trichopoulos D., Khaw K.T., Johansson M., Weiderpass E., Tjonneland A., Riboli E., Lathrop M., Scelo G., Albanes D., Caporaso N.E., Ye Y., Gu J., Wu X., Spitz M.R., Dienemann H., Rosenberger A., Su L., Matakidou A., Eisen T., Stefansson K., Risch A., Chanock S.J., Christiani D.C., Hung R.J., Brennan P., Landi M.T., Houlston R.S., Amos C.I. (2014) Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer Nature genetics; 46(7):736-741. PMID: 24880342

6. Damiola F., Pertesi M., Oliver J., Le Calvez-Kelm F., Voegele C., Young E.L., Robinot N., Forey N., Durand G., Vallee M.P., Tao K., Roane T.C., Williams G.J., Hopper J.L., Southey M.C., Andrulis I.L., John E.M., Goldgar D.E., Lesueur F., Tavtigian S.V. (2014) Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study Breast cancer research; 16(3):R58. PMID: 24894818

7. Bonora E., Rizzato C., Diquigiovanni C., Oudot-Mellakh T., Campa D., Vargiolu M., Guedj M., McKay J.D., Romeo G., Canzian F., Lesueur F. (2014) The FOXE1 locus is a major genetic determinant for familial nonmedullary thyroid carcinoma International journal of cancer; 134(9):2098-2107. PMID: 24127282

8. Damiola F., Byrnes G., Moissonnier M., Pertesi M., Deltour I., Fillon A., Le Calvez-Kelm F., Tenet V., McKay-Chopin S., McKay J.D., Malakhova I., Masyakin V., Cardis E., Lesueur F., Kesminiene A. (2014) Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation International journal of cancer; 134(7):1659-1668. PMID: 24105688

9. Gheit T., Abedi-Ardekani B., Carreira C., Missad C.G., Tommasino M., Torrente M.C. (2014) Comprehensive analysis of HPV expression in laryngeal squamous cell carcinoma J Med.Virol.; 86(4):642-646. PMID: 24374907

10. Agarwal D., Pineda S., Michailidou K., Herranz J., Pita G., Moreno L.T., Alonso M.R., Dennis J., Wang Q., Bolla M.K., Meyer K.B., Menendez-Rodriguez P., Hardisson D., Mendiola M., Gonzalez-Neira A., Lindblom A., Margolin S., Swerdlow A., Ashworth A., Orr N., Jones M., Matsuo K., Ito H., Iwata H., Kondo N., Hartman M., Hui M., Lim W.Y., Iau P.T., Sawyer E., Tomlinson I., Kerin M., Miller N., Kang D., Choi J., Park S.K., Noh D., Hopper J.L., Schmidt D.F., Makalic E., Southey M.C., Teo S.H., Yip C.H., Sivanandan K., Tay W., Brauch H., Bruning T., Hamann U., Dunning A.M., Shah M., Andrulis I.L., Knight J.A., Glendon G., Tchatchou S., Schmidt M.K., Broeks A., Rosenberg E.H., van't Veer L.J., Fasching P.A., Renner S.P., Ekici A.B., Beckmann M.W., Shen C., Hsiung C., Yu J., Hou M., Blot W., Cai Q., Wu A.H., Tseng C., Van Den Berg D., Stram D.O., Cox A., Brock I.W., Reed M.W., Muir K., Lophatananon A., Stewart-Brown S., Siriwanarangsan P., Zheng W., Deming-Halverson S., Shrubsole M.J., Long J., Shu X., Lu W., Gao Y., Zhang B., Radice P., Peterlongo P., Manoukian S., Mariette F., Sangrajrang S., McKay J., Couch F.J., Toland A.E., Yannoukakos D., Fletcher O., Johnson N., Dos Santos Silva I, Peto J., Marme F., Burwinkel B., Guenel P., Truong T., Sanchez M., Mulot C., Bojesen S.E., Nordestgaard B.G., Flyer H., Brenner H., Dieffenbach A.K., Arndt V., Stegmaier C., Mannermaa A., Kataja V., Kosma V., Hartikainen J.M., Lambrechts D., Yesilyurt B.T., Floris G., Leunen K., Chang-Claude J., Rudolph A., Seibold P., Flesch-Janys D., Wang X., Olson J.E., Vachon C., Purrington K., Giles G.G., Severi G., Baglietto L., Haiman C.A., Henderson B.E., Schumacher F., Marchand L.L., Simard J., Dumont M., Goldberg M.S., Labreche F., Winqvist R., Pylkas K., Jukkola-Vuorinen A., Grip M., Devilee P., Tollenaar R.A., Seynaeve C., Garcia-Closas M., Chanock S.J., Lissowska J., Figueroa J.D., Czene K., Eriksson M., Humphreys K., Darabi H., Hooning M.J., Kriege M., Collee J.M., Tilanus-Linthorst M., Li J., Jakubowska A., Lubinski J., Jaworska-Bieniek K., Durda K., Nevanlinna H., Muranen T.A., Aittomaki K., Blomqvist C., Bogdanova N., Dork T., Hall P., Chenevix-Trench G., Easton D.F., Pharroah P.D., Arias-Perez J.I., Zamora P., Benitez J., Milne R.L. (2014) FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium British journal of cancer; 110(4):1088-1100. PMID: 24548884

11. Anantharaman D., Chabrier A., Gaborieau V., Franceschi S., Herrero R., Rajkumar T., Samant T., Mahimkar M.B., Brennan P., McKay J.D. (2014) Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in India PLoS ONE; 9(2):e88240. PMID: 24505444

12. Cozen W., Timofeeva M.N., Li D., Diepstra A., Hazelett D., Delahaye-Sourdeix M., Edlund C.K., Franke L., Rostgaard K., Van Den Berg D.J., Cortessis V.K., Smedby K.E., Glaser S.L., Westra H.J., Robison L.L., Mack T.M., Ghesquieres H., Hwang A.E., Nieters A., de Sanjose S., Lightfoot T., Becker N., Maynadie M., Foretova L., Roman E., Benavente Y., Rand K.A., Nathwani B.N., Glimelius B., Staines A., Boffetta P., Link B.K., Kiemeney L., Ansell S.M., Bhatia S., Strong L.C., Galan P., Vatten L., Habermann T.M., Duell E.J., Lake A., Veenstra R.N., Visser L., Liu Y., Urayama K.Y., Montgomery D., Gaborieau V., Weiss L.M., Byrnes G., Lathrop M., Cocco P., Best T., Skol A.D., Adami H.O., Melbye M., Cerhan J.R., Gallagher A., Taylor G.M., Slager S.L., Brennan P., Coetzee G.A., Conti D.V., Onel K., Jarrett R.F., Hjalgrim H., van den Berg A., McKay J.D. (2014) A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus Nat Commun.; 3856. PMID: 24920014