Research Groups

Section of Genetics - Genetic Cancer Susceptibility Group

Recent Publications - 12 most recent publications

1. Park D.J., Tao K., Le Calvez-Kelm F., Nguyen-Dumont T., Robinot N., Hammet F., Odefrey F., Tsimiklis H., Teo Z.L., Thingholm L.B., Young E.L., Voegele C., Lonie A., Pope B.J., Roane T.C., Bell R., Hu H., Shankaracharya, Huff C.D., Ellis J., Li J., Makunin I.V., John E.M., Andrulis I.L., Terry M.B., Daly M., Buys S.S., Snyder C., Lynch H.T., Devilee P., Giles G.G., Hopper J.L., Feng B.J., Lesueur F., Tavtigian S.V., Southey M.C., Goldgar D.E. (2014) Rare Mutations in RINT1 Predispose Carriers to Breast and Lynch Syndrome-Spectrum Cancers Cancer Discov.; 4(7):804-815. PMID: 25050558

2. Babron M.C., Kazma R., Gaborieau V., McKay J., Brennan P., Sarasin A., Benhamou S. (2014) Genetic variants in DNA repair pathways and risk of upper aerodigestive tract cancers: combined analysis of data from two genome-wide association studies in European populations Carcinogenesis; 35(7):1523-1527. PMID: 24658182

3. Bonora E., Rizzato C., Diquigiovanni C., Oudot-Mellakh T., Campa D., Vargiolu M., Guedj M., McKay J.D., Romeo G., Canzian F., Lesueur F. (2014) The FOXE1 locus is a major genetic determinant for familial nonmedullary thyroid carcinoma International journal of cancer; 134(9):2098-2107. PMID: 24127282

4. Damiola F., Byrnes G., Moissonnier M., Pertesi M., Deltour I., Fillon A., Le Calvez-Kelm F., Tenet V., McKay-Chopin S., McKay J.D., Malakhova I., Masyakin V., Cardis E., Lesueur F., Kesminiene A. (2014) Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation International journal of cancer; 134(7):1659-1668. PMID: 24105688

5. Agarwal D., Pineda S., Michailidou K., Herranz J., Pita G., Moreno L.T., Alonso M.R., Dennis J., Wang Q., Bolla M.K., Meyer K.B., Menendez-Rodriguez P., Hardisson D., Mendiola M., Gonzalez-Neira A., Lindblom A., Margolin S., Swerdlow A., Ashworth A., Orr N., Jones M., Matsuo K., Ito H., Iwata H., Kondo N., Hartman M., Hui M., Lim W.Y., Iau P.T., Sawyer E., Tomlinson I., Kerin M., Miller N., Kang D., Choi J., Park S.K., Noh D., Hopper J.L., Schmidt D.F., Makalic E., Southey M.C., Teo S.H., Yip C.H., Sivanandan K., Tay W., Brauch H., Bruning T., Hamann U., Dunning A.M., Shah M., Andrulis I.L., Knight J.A., Glendon G., Tchatchou S., Schmidt M.K., Broeks A., Rosenberg E.H., van't Veer L.J., Fasching P.A., Renner S.P., Ekici A.B., Beckmann M.W., Shen C., Hsiung C., Yu J., Hou M., Blot W., Cai Q., Wu A.H., Tseng C., Van Den Berg D., Stram D.O., Cox A., Brock I.W., Reed M.W., Muir K., Lophatananon A., Stewart-Brown S., Siriwanarangsan P., Zheng W., Deming-Halverson S., Shrubsole M.J., Long J., Shu X., Lu W., Gao Y., Zhang B., Radice P., Peterlongo P., Manoukian S., Mariette F., Sangrajrang S., McKay J., Couch F.J., Toland A.E., Yannoukakos D., Fletcher O., Johnson N., Dos Santos Silva I, Peto J., Marme F., Burwinkel B., Guenel P., Truong T., Sanchez M., Mulot C., Bojesen S.E., Nordestgaard B.G., Flyer H., Brenner H., Dieffenbach A.K., Arndt V., Stegmaier C., Mannermaa A., Kataja V., Kosma V., Hartikainen J.M., Lambrechts D., Yesilyurt B.T., Floris G., Leunen K., Chang-Claude J., Rudolph A., Seibold P., Flesch-Janys D., Wang X., Olson J.E., Vachon C., Purrington K., Giles G.G., Severi G., Baglietto L., Haiman C.A., Henderson B.E., Schumacher F., Marchand L.L., Simard J., Dumont M., Goldberg M.S., Labreche F., Winqvist R., Pylkas K., Jukkola-Vuorinen A., Grip M., Devilee P., Tollenaar R.A., Seynaeve C., Garcia-Closas M., Chanock S.J., Lissowska J., Figueroa J.D., Czene K., Eriksson M., Humphreys K., Darabi H., Hooning M.J., Kriege M., Collee J.M., Tilanus-Linthorst M., Li J., Jakubowska A., Lubinski J., Jaworska-Bieniek K., Durda K., Nevanlinna H., Muranen T.A., Aittomaki K., Blomqvist C., Bogdanova N., Dork T., Hall P., Chenevix-Trench G., Easton D.F., Pharroah P.D., Arias-Perez J.I., Zamora P., Benitez J., Milne R.L. (2014) FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium British journal of cancer; 110(4):1088-1100. PMID: 24548884

6. Martin M., Ancey P.B., Cros M.P., Durand G., Le Calvez-Kelm F., Hernandez-Vargas H., Herceg Z. (2014) Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch BMC.Genomics; 435. PMID: 24898317

7. Muhleisen T.W., Leber M., Schulze T.G., Strohmaier J., Degenhardt F., Treutlein J., Mattheisen M., Forstner A.J., Schumacher J., Breuer R., Meier S., Herms S., Hoffmann P., Lacour A., Witt S.H., Reif A., Muller-Myhsok B., Lucae S., Maier W., Schwarz M., Vedder H., Kammerer-Ciernioch J., Pfennig A., Bauer M., Hautzinger M., Moebus S., Priebe L., Czerski P.M., Hauser J., Lissowska J., Szeszenia-Dabrowska N., Brennan P., McKay J.D., Wright A., Mitchell P.B., Fullerton J.M., Schofield P.R., Montgomery G.W., Medland S.E., Gordon S.D., Martin N.G., Krasnow V., Chuchalin A., Babadjanova G., Pantelejeva G., Abramova L.I., Tiganov A.S., Polonikov A., Khusnutdinova E., Alda M., Grof P., Rouleau G.A., Turecki G., Laprise C., Rivas F., Mayoral F., Kogevinas M., Grigoroiu-Serbanescu M., Propping P., Becker T., Rietschel M., Nothen M.M., Cichon S. (2014) Genome-wide association study reveals two new risk loci for bipolar disorder Nat Commun.; 3339. PMID: 24618891

8. Cozen W., Timofeeva M.N., Li D., Diepstra A., Hazelett D., Delahaye-Sourdeix M., Edlund C.K., Franke L., Rostgaard K., Van Den Berg D.J., Cortessis V.K., Smedby K.E., Glaser S.L., Westra H.J., Robison L.L., Mack T.M., Ghesquieres H., Hwang A.E., Nieters A., de Sanjose S., Lightfoot T., Becker N., Maynadie M., Foretova L., Roman E., Benavente Y., Rand K.A., Nathwani B.N., Glimelius B., Staines A., Boffetta P., Link B.K., Kiemeney L., Ansell S.M., Bhatia S., Strong L.C., Galan P., Vatten L., Habermann T.M., Duell E.J., Lake A., Veenstra R.N., Visser L., Liu Y., Urayama K.Y., Montgomery D., Gaborieau V., Weiss L.M., Byrnes G., Lathrop M., Cocco P., Best T., Skol A.D., Adami H.O., Melbye M., Cerhan J.R., Gallagher A., Taylor G.M., Slager S.L., Brennan P., Coetzee G.A., Conti D.V., Onel K., Jarrett R.F., Hjalgrim H., van den Berg A., McKay J.D. (2014) A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus Nat Commun.; 3856. PMID: 24920014

9. Anantharaman D., Chabrier A., Gaborieau V., Franceschi S., Herrero R., Rajkumar T., Samant T., Mahimkar M.B., Brennan P., McKay J.D. (2014) Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in India PLoS ONE; 9(2):e88240. PMID: 24505444

10. Olivier M., Weninger A., Ardin M., Huskova H., Castells X., Vallee M.P., McKay J., Nedelko T., Muehlbauer K.R., Marusawa H., Alexander J., Hazelwood L., Byrnes G., Hollstein M., Zavadil J. (2014) Modelling mutational landscapes of human cancers in vitro Sci Rep.; 4482. PMID: 24670820

11. Meyer K.B., O'Reilly M., Michailidou K., Carlebur S., Edwards S.L., French J.D., Prathalingham R., Dennis J., Bolla M.K., Wang Q., de Santiago I, Hopper J.L., Tsimiklis H., Apicella C., Southey M.C., Schmidt M.K., Broeks A., Van 't Veer L.J., Hogervorst F.B., Muir K., Lophatananon A., Stewart-Brown S., Siriwanarangsan P., Fasching P.A., Lux M.P., Ekici A.B., Beckmann M.W., Peto J., Dos Santos Silva I, Fletcher O., Johnson N., Sawyer E.J., Tomlinson I., Kerin M.J., Miller N., Marme F., Schneeweiss A., Sohn C., Burwinkel B., Guenel P., Truong T., Laurent-Puig P., Menegaux F., Bojesen S.E., Nordestgaard B.G., Nielsen S.F., Flyger H., Milne R.L., Zamora M.P., Arias J.I., Benitez J., Neuhausen S., Anton-Culver H., Ziogas A., Dur C.C., Brenner H., Muller H., Arndt V., Stegmaier C., Meindl A., Schmutzler R.K., Engel C., Ditsch N., Brauch H., Bruning T., Ko Y.D., Nevanlinna H., Muranen T.A., Aittomaki K., Blomqvist C., Matsuo K., Ito H., Iwata H., Yatabe Y., Dork T., Helbig S., Bogdanova N.V., Lindblom A., Margolin S., Mannermaa A., Kataja V., Kosma V.M., Hartikainen J.M., Chenevix-Trench G., Wu A.H., Tseng C.C., Van Den Berg D., Stram D.O., Lambrechts D., Thienpont B., Christiaens M.R., Smeets A., Chang-Claude J., Rudolph A., Seibold P., Flesch-Janys D., Radice P., Peterlongo P., Bonanni B., Bernard L., Couch F.J., Olson J.E., Wang X., Purrington K., Giles G.G., Severi G., Baglietto L., McLean C., Haiman C.A., Henderson B.E., Schumacher F., Le Marchand L., Simard J., Goldberg M.S., Labreche F., Dumont M., Teo S.H., Yip C.H., Phuah S.Y., Kristensen V., Grenaker Alnaes G., Borresen-Dale A.L., Zheng W., Deming-Halverson S., Shrubsole M., Long J., Winqvist R., Pylkas K., Jukkola-Vuorinen A., Kauppila S., Andrulis I.L., Knight J.A., Glendon G., Tchatchou S., Devilee P., Tollenaar R.A., Seynaeve C.M., Garcia-Closas M., Figueroa J., Chanock S.J., Lissowska J., Czene K., Darabi H., Eriksson K., Hooning M.J., Martens J.W., van den Ouweland A.M., van Deurzen C.H., Hall P., Li J., Liu J., Humphreys K., Shu X.O., Lu W., Gao Y.T., Cai H., Cox A., Reed M.W., Blot W., Signorello L.B., Cai Q., Pharoah P.D., Ghoussaini M., Harrington P., Tyrer J., Kang D., Choi J.Y., Park S.K., Noh D.Y., Hartman M., Hui M., Lim W.Y., Buhari S.A., Hamann U., Forsti A., Rudiger T., Ulmer H.U., Jakubowska A., Lubinski J., Jaworska K., Durda K., Sangrajrang S., Gaborieau V., Brennan P., McKay J., Vachon C., Slager S., Fostira F., Pilarski R., Shen C.Y., Hsiung C.N., Wu P.E., Hou M.F., Swerdlow A., Ashworth A., Orr N., Schoemaker M.J., Ponder B.A., Dunning A.M., Easton D.F. (2013) Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1 Am.J Hum Genet.; 93(6):1046-1060. PMID: 24290378

12. Ortiz-Cuaran S., Cox D., Villar S., Friesen M.D., Durand G., Chabrier A., Khuhaprema T., Sangrajrang S., Ognjanovic S., Groopman J.D., Hainaut P., Le Calvez-Kelm F. (2013) Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma Genes Chromosomes.Cancer; 52(10):912-919. PMID: 23836507