Research Groups

Recent Publications:

1. Cazzaniga M, Gheit T, Casadio C, Khan N, Macis D, Valenti F, Miller MJ, Sylla BS, Akiba S, Bonanni B, Decensi A, Veronesi U and Tommasino M (2009) Analysis of the presence of cutaneous and mucosal papillomavirus types in ductal lavage fluid, milk and colostrum to evaluate its role in breast carcinogenesis. Breast Cancer Res Treat, 114: 599-605.

2. Cardone RA, Busco G, Greco MR, Bellizzi A, Accardi R, Cafarelli A, Monterisi S, Carratù P, Casavola V, Paradiso A, Tommasino M and Reshkin SJ (2008) HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha. PloS One, 3(10):e3529.

3. Dong W, Arpin C, Accardi R, Gissmann L, Sylla BS, Marvel J and Tommasino M (2008) Loss of p53 or p73 in human papillomavirus type 38 E6 and E7 transgenic mice partially restores the UV-activated cell cycle checkpoints. Oncogene, 27: 2923-8.

4. Gabet AS, Accardi R, Bellopede A, Popp S, Boukamp P, Sylla BS, Londoño-Vallejo JA and Tommasino M (2008) Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin Human Papillomavirus type 38. FASEB J, 22: 622-32.

5. Hasan UA, Caux C, Perrot I, Doffin AC, Menetrier-Caux C, Trinchieri G, Tommasino M and Vlach J (2007) Cell proliferation and survival induced by TLRs is antagonized by type I Interferons. Proc Natl Acad Sci USA, 104: 8047-52.

6. Hasan UA, Bates E, Takeshita F, Biliato A, Accardi R, Bouvard V, Mansour M, Vincent I, Gissmann L, Iftner T, Sideri M, Stubenrauch F and Tommasino M (2007) TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16. J Immunol, 178: 3186-97.

7. Lee S, Huang H, Niu Y, Tommasino M, Lenoir G and Sylla BS (2007) Dok1 expression and mutation in Burkitt's lymphoma cell lines. Cancer Lett, 245: 44-50.

8. Niu Y, Roy F, Saltel F, Andrieu-Soler C, Dong W, Chantegrel AL, Accardi R, Thépot A, Foiselle N, Tommasino M, Jurdic P and Sylla BS (2006) Nuclear export signal and phosphorylation regulate Dok1 subcellular localization and functions. Mol Cell Biol, 26: 4288-301.

9. Accardi R, Dong W, Smet A, Cui R, Hautefeuille A, Gabet AS, Sylla BS, Gissmann L, Hainaut P and Tommasino M (2006) Skin human papillomavirus type 38 alters p53 functions via accumulation of _Np73. EMBO Rep., 7: 334-40.

10. Dong W, Klotz U, Accardi R, Caldeira S, Tong WM, Wang ZQ, Jansen L, Dürst M, Sylla BS, Gissmann L and Tommasino M (2005) Skin hyperproliferation and susceptibility to chemical carcinogenesis in transgenic mice expressing E6 and E7 of human papillomavirus type 38. J Virol 79: 14899-908.