Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group
The Molecular Mechanisms and Biomarkers Group (MMB) conducts studies aimed at better understanding mechanisms of carcinogenesis and at identifying biomarkers applicable in molecular epidemiology and cancer prevention. This is achieved through the study of molecular and genetic changes, gene function and gene-environment interactions. MMB also aims to investigate the effects of environmental exposures on molecular changes to discover and validate new cancer biomarkers that can be used as biomarkers of exposures. To this end, the MMB Group develops a multi-faceted research programme which builds on new and existing collaborative studies and combines experimental (mechanistic) studies with molecular epidemiology studies on human biospecimens using genomic platforms, molecular/cell biology and biochemistry tools.