Research Groups

Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group

Recent Publications - 12 most recent publications

1. Hollstein M., Alexandrov L. B., Wild C. P., Ardin M., Zavadil J. (2017) Base changes in tumour DNA have the power to reveal the causes and evolution of cancer Oncogene; 36(2):158-167. PMID: 27270430

2. Vargova J., Vargova K., Dusilkova N., Kulvait V., Pospisil V., Zavadil J., Trneny M., Klener P., Stopka T. (2016) Differential expression, localization and activity of MARCKS between mantle cell lymphoma and chronic lymphocytic leukemia Blood Cancer J; 6(9):e475. PMID: 27662204

3. Bouaoun L., Sonkin D., Ardin M., Hollstein M., Byrnes G., Zavadil J., Olivier M. (2016) TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data Hum Mutat; 37(9):865-76. PMID: 27328919

4. Fernandez-Cuesta L., Perdomo S., Avogbe P. H., Leblay N., Delhomme T. M., Gaborieau V., Abedi-Ardekani B., Chanudet E., Olivier M., Zaridze D., Mukeria A., Vilensky M., Holcatova I., Polesel J., Simonato L., Canova C., Lagiou P., Brambilla C., Brambilla E., Byrnes G., Scelo G., Le Calvez-Kelm F., Foll M., McKay J. D., Brennan P. (2016) Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer EBioMedicine; 117-23. PMID: 27377626

5. He S., Limi S., McGreal R. S., Xie Q., Brennan L. A., Kantorow W. L., Kokavec J., Majumdar R., Hou H., Edelmann W., Liu W., Ashery-Padan R., Zavadil J., Kantorow M., Skoultchi A. I., Stopka T., Cvekl A. (2016) Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation Development; 143(11):1937-1947. PMID: 27246713

6. Ma X., Le Teuff G., Lacas B., Tsao M. S., Graziano S., Pignon J. P., Douillard J. Y., Le Chevalier T., Seymour L., Filipits M., Pirker R., Janne P. A., Shepherd F. A., Brambilla E., Soria J. C., Hainaut P. (2016) Prognostic and Predictive Effect of TP53 Mutations in Patients with Non-Small Cell Lung Cancer from Adjuvant Cisplatin-Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis J Thorac Oncol; 11(6):850-61. PMID: 26899019

7. Tissot C., Villar S., Olivier M., Couraud S. (2016) [Free circulating DNA as a tool for lung cancer patients management] Rev Pneumol Clin; 72(1):61-71. PMID: 26190335

8. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

9. Vojtechova Z., Sabol I., Salakova M., Smahelova J., Zavadil J., Turek L., Grega M., Klozar J., Prochazka B., Tachezy R. (2016) Comparison of the miRNA profiles in HPV-positive and HPV-negative tonsillar tumors and a model system of human keratinocyte clones BMC cancer; 382. PMID: 27377959

10. Castells X., Karanovic S., Ardin M., Tomic K., Xylinas E., Durand G., Villar S., Forey N., Le Calvez-Kelm F., Voegele C., Karlovic K., Misic M., Dittrich D., Dolgalev I., McKay J., Shariat S. F., Sidorenko V. S., Fernandes A., Heguy A., Dickman K. G., Olivier M., Grollman A. P., Jelakovic B., Zavadil J. (2015) Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid Cancer Epidemiol Biomarkers Prev; 24(12):1873-81. PMID: 26383547

11. Tissot C., Toffart A. C., Villar S., Souquet P. J., Merle P., Moro-Sibilot D., Perol M., Zavadil J., Brambilla C., Olivier M., Couraud S. (2015) Circulating free DNA concentration is an independent prognostic biomarker in lung cancer Eur Respir J; 46(6):1773-80. PMID: 26493785

12. Traore F., Gormally E., Villar S., Friesen M. D., Groopman J. D., Vernet G., Diallo S., Hainaut P., Maiga M. Y. (2015) Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali BMC Infect Dis; 180. PMID: 25886382