Research Groups

Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group

Recent Publications - 12 most recent publications

1. Shang S., Plymoth A., Ge S., Feng Z., Rosen H.R., Sangrajrang S., Hainaut P., Marrero J.A., Beretta L. (2012) Identification of osteopontin as a novel marker for early hepatocellular carcinoma Hepatology; 55(2):483-490. PMID: 21953299

2. Blandino G., Deppert W., Hainaut P., Levine A., Lozano G., Olivier M., Rotter V., Wiman K., Oren M. (2012) Mutant p53 protein, master regulator of human malignancies: a report on the fifth Mutant p53 Workshop Cell death and differentiation; 19(1):180-183. PMID: 22095277

3. Hainaut P., Plymoth A. (2012) Cancer as a metabolic disease Current opinion in oncology; 24(1):56-57. PMID: 22143370

4. Balassiano K., Lima S., Jenab M., Overvad K., Tjonneland A., Boutron-Ruault M.C., Clavel-Chapelon F., Canzian F., Kaaks R., Boeing H., Meidtner K., Trichopoulou A., Laglou P., Vineis P., Panico S., Palli D., Grioni S., Tumino R., Lund E., Bueno-de-Mesquita H.B., Numans M.E., Peeters P.H., Ramon Quiros J., Sanchez M.A., Navarro C., Ardanaz E., Dorronsoro M., Hallmans G., Stenling R., Ehrnstrom R., Regner S., Allen N.E., Travis R.C., Khaw K.T., Offerhaus G.J., Sala N., Riboli E., Hainaut P., Scoazec J.Y., Sylla B.S., Gonzalez C.A., Herceg Z. (2011) Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Cancer letters; 311(1):85-95. PMID: 21831520

5. da Silva E.M., Achatz M.I., Martel-Planche G., Montagnini A.L., Olivier M., Prolla P.A., Hainaut P., Soares F.A. (2011) TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype: case report BMC cancer; 11(1):449. PMID: 22004116

6. Hafsi H., Hainaut P. (2011) Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence Antioxidants & redox signaling; 15(6):1655-1667. PMID: 21194382

7. Krais A.M., Hautefeuille A.H., Cros M.P., Krutovskikh V., Tournier J.M., Birembaut P., Thepot A., Paliwal A., Herceg Z., Boffetta P., Brennan P., Hainaut P.L. (2011) CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression Carcinogenesis; 32(9):1388-1395. PMID: 21586512

8. Moore H.M., Kelly A.B., Jewell S.D., McShane L.M., Clark D.P., Greenspan R., Hayes D.F., Hainaut P., Kim P., Mansfield E., Potapova O., Riegman P., Rubinstein Y., Seijo E., Somiari S., Watson P., Weier H.U., Zhu C., Vaught J. (2011) Biospecimen Reporting for Improved Study Quality (BRISQ) J Proteome Res; 10(8):3429-3438. PMID: 21574648

9. Beau-Faller M., Degeorges A., Rolland E., Mounawar M., Antoine M., Poulot V., Mauguen A., Barbu V., Coulet F., Pretet J.L., Bieche I., Blons H., Boyer J.C., Buisine M.P., de Fraipont F., Lizard S., Olschwang S., Saulnier P., Prunier-Mirebeau D., Richard N., Danel C., Brambilla E., Chouaid C., Zalcman G., Hainaut P., Michiels S., Cadranel J. (2011) Cross-Validation Study for Epidermal Growth Factor Receptor and KRAS Mutation Detection in 74 Blinded Non-small Cell Lung Carcinoma Samples: A Total of 5550 Exons Sequenced by 15 Molecular French Laboratories (Evaluation of the EGFR Mutation Status for the Administration of EGFR-TKIs in Non-Small Cell Lung Carcinoma [ERMETIC] Project-Part 1) J Thorac Oncol; 6(6):1006-1015. PMID: 21532509

10. Nogueira da Costa A., Mijal R.S., Keen J.N., Findlay J.B., Wild C.P. (2011) Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol Proteomics; 11(10):1903-1914. PMID: 21462343

11. Brennan P., Hainaut P., Boffetta P. (2011) Genetics of lung-cancer susceptibility Lancet oncology; 12(4):399-408. PMID: 20951091

12. Fernandez-Cuesta L., Anaganti S., Hainaut P., Olivier M. (2011) p53 status influences response to tamoxifen but not to fulvestrant in breast cancer cell lines International journal of cancer; 128(8):1813-1821. PMID: 20549698