Research Groups

Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group

Recent Publications - 12 most recent publications

1. Sagne C., Marcel V., Bota M., Martel-Planche G., Nobrega A., Palmero E.I., Perriaud L., Boniol M., Vagner S., Cox D.G., Chan C.S., Mergny J.L., Olivier M., Ashton-Prolla P., Hall J., Hainaut P., Achatz M.I. (2014) Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures Carcinogenesis; 35(4):807-815. PMID: 24336192

2. Cortot A.B., Younes M., Martel-Planche G., Guibert B., Isaac S., Souquet P.J., Commo F., Girard P., Fouret P., Brambilla E., Hainaut P., Soria J.C. (2014) Mutation of TP53 and Alteration of p14(arf) Expression in EGFR- and KRAS-mutated lung adenocarcinomas. Clin Lung Cancer; 15(2):124-130. PMID: 24169260

3. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650. PMID: 24163401

4. Giacomazzi J., Graudenz M.S., Osorio C.A., Koehler-Santos P., Palmero E.I., Zagonel-Oliveira M., Michelli R.A., Neto C.S., Fernandes G.C., Achatz M.I., Martel-Planche G., Soares F.A., Caleffi M., Goldim J.R., Hainaut P., Camey S.A., Ashton-Prolla P. (2014) Prevalence of the TP53 p.R337H Mutation in Breast Cancer Patients in Brazil PLoS ONE; 9(6):e99893. PMID: 24936644

5. Sighoko D., Kamate B., Traore C., Malle B., Coulibaly B., Karidiatou A., Diallo C., Bah E., McCormack V., Muwonge R., Bourgeois D., Gormally E., Curado M.P., Bayo S., Hainaut P. (2013) Breast cancer in pre-menopausal women in West Africa: analysis of temporal trends and evaluation of risk factors associated with reproductive life Breast; 22(5):828-835. PMID: 23489760

6. Shepherd F.A., Domerg C., Hainaut P., Janne P.A., Pignon J.P., Graziano S., Douillard J.Y., Brambilla E., Le Chevalier T., Seymour L., Bourredjem A., Le Teuff G., Pirker R., Filipits M., Rosell R., Kratzke R., Bandarchi B., Ma X., Capelletti M., Soria J.C., Tsao M.S. (2013) Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy Journal of clinical oncology; 31(17):2173-2181. PMID: 23630215

7. Dichtel-Danjoy M.L., Ma D., Dourlen P., Chatelain G., Napoletano F., Robin M., Corbet M., Levet C., Hafsi H., Hainaut P., Ryoo H.D., Bourdon J.C., Mollereau B. (2013) Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation Cell Death.Differ.; 20(1):108-116. PMID: 22898807

8. Hafsi H., Santos-Silva D., Courtois-Cox S., Hainaut P. (2013) Effects of Delta40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53 BMC.Cancer; 134. PMID: 23514281

9. Shang S., Plymoth A., Ge S., Feng Z., Rosen H.R., Sangrajrang S., Hainaut P., Marrero J.A., Beretta L. (2012) Identification of osteopontin as a novel marker for early hepatocellular carcinoma Hepatology; 55(2):483-490. PMID: 21953299

10. Blandino G., Deppert W., Hainaut P., Levine A., Lozano G., Olivier M., Rotter V., Wiman K., Oren M. (2012) Mutant p53 protein, master regulator of human malignancies: a report on the fifth Mutant p53 Workshop Cell death and differentiation; 19(1):180-183. PMID: 22095277

11. Hainaut P., Plymoth A. (2012) Cancer as a metabolic disease Current opinion in oncology; 24(1):56-57. PMID: 22143370

12. Balassiano K., Lima S., Jenab M., Overvad K., Tjonneland A., Boutron-Ruault M.C., Clavel-Chapelon F., Canzian F., Kaaks R., Boeing H., Meidtner K., Trichopoulou A., Laglou P., Vineis P., Panico S., Palli D., Grioni S., Tumino R., Lund E., Bueno-de-Mesquita H.B., Numans M.E., Peeters P.H., Ramon Quiros J., Sanchez M.A., Navarro C., Ardanaz E., Dorronsoro M., Hallmans G., Stenling R., Ehrnstrom R., Regner S., Allen N.E., Travis R.C., Khaw K.T., Offerhaus G.J., Sala N., Riboli E., Hainaut P., Scoazec J.Y., Sylla B.S., Gonzalez C.A., Herceg Z. (2011) Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Cancer letters; 311(1):85-95. PMID: 21831520