Research Groups

Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group

Recent Publications - 12 most recent publications

1. Bouaoun L., Sonkin D., Ardin M., Hollstein M., Byrnes G., Zavadil J., Olivier M. (2016) TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data Hum Mutat; 37(9):865-76. PMID: 27328919

2. Fernandez-Cuesta L., Perdomo S., Avogbe P. H., Leblay N., Delhomme T. M., Gaborieau V., Abedi-Ardekani B., Chanudet E., Olivier M., Zaridze D., Mukeria A., Vilensky M., Holcatova I., Polesel J., Simonato L., Canova C., Lagiou P., Brambilla C., Brambilla E., Byrnes G., Scelo G., Le Calvez-Kelm F., Foll M., McKay J. D., Brennan P. (2016) Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer EBioMedicine; 117-23. PMID: 27377626

3. He S., Limi S., McGreal R. S., Xie Q., Brennan L. A., Kantorow W. L., Kokavec J., Majumdar R., Hou H. Jr., Edelmann W., Liu W., Ashery-Padan R., Zavadil J., Kantorow M., Skoultchi A. I., Stopka T., Cvekl A. (2016) Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation Development; 143(11):1937-47. PMID: 27246713

4. Tissot C., Villar S., Olivier M., Couraud S. (2016) [Free circulating DNA as a tool for lung cancer patients management] Rev Pneumol Clin; 72(1):61-71. PMID: 26190335

5. Ardin M., Cahais V., Castells X., Bouaoun L., Byrnes G., Herceg Z., Zavadil J., Olivier M. (2016) MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes BMC Bioinformatics; 170. PMID: 27091472

6. Vojtechova Z., Sabol I., Salakova M., Smahelova J., Zavadil J., Turek L., Grega M., Klozar J., Prochazka B., Tachezy R. (2016) Comparison of the miRNA profiles in HPV-positive and HPV-negative tonsillar tumors and a model system of human keratinocyte clones BMC cancer; 382. PMID: 27377959

7. Castells X., Karanovic S., Ardin M., Tomic K., Xylinas E., Durand G., Villar S., Forey N., Le Calvez-Kelm F., Voegele C., Karlovic K., Misic M., Dittrich D., Dolgalev I., McKay J., Shariat S. F., Sidorenko V. S., Fernandes A., Heguy A., Dickman K. G., Olivier M., Grollman A. P., Jelakovic B., Zavadil J. (2015) Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid Cancer Epidemiol Biomarkers Prev; 24(12):1873-81. PMID: 26383547

8. Tissot C., Toffart A. C., Villar S., Souquet P. J., Merle P., Moro-Sibilot D., Perol M., Zavadil J., Brambilla C., Olivier M., Couraud S. (2015) Circulating free DNA concentration is an independent prognostic biomarker in lung cancer Eur Respir J; 46(6):1773-80. PMID: 26493785

9. Jelakovic B., Castells X., Tomic K., Ardin M., Karanovic S., Zavadil J. (2015) Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid Int. J Cancer; 136(12):2967-2972.

10. Krais A.M., Muhlbauer K.R., Kucab J.E., Chinbuah H., Cornelius M.G., Wei Q.X., Hollstein M., Phillips D.H., Arlt V.M., Schmeiser H.H. (2015) Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts Toxicol In Vitro; 29(1):34-43. PMID: 25230394

11. Mariga A., Zavadil J., Ginsberg S.D., Chao M.V. (2015) Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function Dev. Neurobiol; 75(2):173-192. PMID: 25059794

12. Ose J., Fortner R.T., Rinaldi S., Schock H., Overvad K., Tjonneland A., Hansen L., Dossus L., Fournier A., Baglietto L., Romieu I., Kuhn E., Boeing H., Trichopoulou A., Lagiou P., Trichopoulos D., Palli D., Masala G., Sieri S., Tumino R., Sacerdote C., Mattiello A., Ramon Quiros J., Obon-Santacana M., Larranaga N., Chirlaque M.D., Sanchez M.J., Barricarte A., Peeters P.H., Bueno-de-Mesquita H.B., Onland-Moret N.C., Brandstedt J., Lundin E., Idahl A., Weiderpass E., Gram I.T., Lund E., Kaw K.T., Travis R.C., Merritt M.A., Gunther M.J., Riboli E., Kaaks R. (2015) Endogenous androgens and risk of epithelial invasive ovarian cancer by tumor characteristics in the European Prospective Investigation into Cancer and Nutrition Int. J Cancer; 136(2):399-410.