Research Groups

Mechanisms of Carcinogenesis - Molecular Mechanisms and Biomarkers Group

Previous Publications - All publications 2015-2011

1. Wild C., Brennan P., Plummer M., Bray F., Straif K., Zavadil J. (2015) Cancer risk: role of chance overstated Science; 347(6223):728. PMID: 25656657

2. Krais A.M., Muhlbauer K.R., Kucab J.E., Chinbuah H., Cornelius M.G., Wei Q.X., Hollstein M., Phillips D.H., Arlt V.M., Schmeiser H.H. (2015) Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts Toxicol In Vitro; 29(1):34-43. PMID: 25230394

3. Mariga A., Zavadil J., Ginsberg S.D., Chao M.V. (2015) Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function Dev.Neurobiol.; 75(2):173-192. PMID: 25059794

4. Ose J., Fortner R.T., Schock H., Peeters P.H., Onland-Moret N.C., Bueno-de-Mesquita H.B., Weiderpass E., Gram I.T., Overvad K., Tjonneland A., Dossus L., Fournier A., Baglietto L., Trichopoulou A., Benetou V., Trichopoulos D., Boeing H., Masala G., Krogh V., Matiello A., Tumino R., Popovic M., Obon-Santacana M., Larranaga N., Ardanaz E., Sanchez M., Menendez V., Chirlaque M., Travis R.C., Khaw K., Brandstedt J., Idahl A., Lundin E., Rinaldi S., Kuhn E., Romieu I., Gunter M.J., Merritt M.A., Riboli E., Kaaks R. (2015) Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: results from the EPIC cohort British journal of cancer; 112(1):162-166. PMID: 25349976

5. Izetti P., Hautefeuille A., Abujamra A.L., de Farias C.B., Giacomazzi J., Alemar B., Lenz G., Roesler R., Schwartsmann G., Osvaldt A.B., Hainaut P., Ashton-Prolla P. (2014) PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines Invest New Drugs; 32(5):783-794. PMID: 24838627

6. SEQC/MAQC-III Consortium (2014) A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium Nat Biotechnol.; 32(9):903-914. PMID: 25150838

7. Couraud S., Vaca-Paniagua F., Villar S., Oliver J., Schuster T., Blanche H., Girard N., Tredaniel J., Guilleminault L., Gervais R., Prim N., Vincent M., Margery J., Larive S., Foucher P., Duvert B., Vallee M., Le Calvez-Kelm F., McKay J., Missy P., Morin F., Zalcman G., Olivier M., Souquet P.J. (2014) Noninvasive Diagnosis of Actionable Mutations by Deep Sequencing of Circulating Free DNA in Lung Cancer from Never-Smokers: A Proof-of-Concept Study from BioCAST/IFCT-1002 Clinical cancer research; 20(17):4613-4624. PMID: 25013125

8. Ma X., Rousseau V., Sun H., Lantuejoul S., Filipits M., Pirker R., Popper H., Mendiboure J., Vataire A.L., Le Chevalier T., Soria J.C., Brambilla E., Dunant A., Hainaut P. (2014) Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer Mol.Oncol; 8(3):555-564. PMID: 24495481

9. Sagne C., Marcel V., Bota M., Martel-Planche G., Nobrega A., Palmero E.I., Perriaud L., Boniol M., Vagner S., Cox D.G., Chan C.S., Mergny J.L., Olivier M., Ashton-Prolla P., Hall J., Hainaut P., Achatz M.I. (2014) Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures Carcinogenesis; 35(4):807-815. PMID: 24336192

10. Cortot A.B., Younes M., Martel-Planche G., Guibert B., Isaac S., Souquet P.J., Commo F., Girard P., Fouret P., Brambilla E., Hainaut P., Soria J.C. (2014) Mutation of TP53 and Alteration of p14(arf) Expression in EGFR- and KRAS-mutated lung adenocarcinomas. Clin Lung Cancer; 15(2):124-130. PMID: 24169260

11. Scelo G., Riazalhosseini Y., Greger L., Letourneau L., Gonzalez-Porta M., Wozniak M.B., Bourgey M., Harnden P., Egevad L., Jackson S.M., Karimzadeh M., Arseneault M., Lepage P., How-Kit A., Daunay A., Renault V., Blanche H., Tubacher E., Sehmoun J., Viksna J., Celms E., Opmanis M., Zarins A., Vasudev N.S., Seywright M., Abedi-Ardekani B., Carreira C., Selby P.J., Cartledge J.J., Byrnes G., Zavadil J., Su J., Holcatova I., Brisuda A., Zaridze D., Moukeria A., Foretova L., Navratilova M., Mates D., Jinga V., Artemov A., Nedoluzhko A., Mazur A., Rastorguev S., Boulygina E., Heath S., Gut M., Bihoreau M.T., Lechner D., Foglio M., Gut I.G., Skryabin K., Prokhortchouk E., Cambon-Thomsen A., Rung J., Bourque G., Brennan P., Tost J., Banks R.E., Brazma A., Lathrop G.M. (2014) Variation in genomic landscape of clear cell renal cell carcinoma across Europe Nat Commun.; 5135. PMID: 25351205

12. Karanovic S., Tomic K., Dittrich D., Borovecki F., Zavadil J., Vukovic-Lela I., Karlovic K., Knezevic M., Jelakovic B. (2014) Endemic (Balkan) nephropathy is aristolochic acid nephropathy Prilozi.; 35(1):43-46. PMID: 24798595

13. Zavadil J. (2014) Multi-'Omics Approaches to Environmental Cancer Risk Factors: A Spotlight on Exposure to Aristolochic Acid and Its Biological Consequences Environ Mol Mutagen; S23 (S15).

14. Mimoso C., Lee D.D., Zavadil J., Tomic-Canic M., Blumenberg M. (2014) Analysis and meta-analysis of transcriptional profiling in human epidermis Methods Mol.Biol.; 61-97. PMID: 24297317

15. Olivier M., Weninger A., Ardin M., Huskova H., Castells X., Vallee M.P., McKay J., Nedelko T., Muehlbauer K.R., Marusawa H., Alexander J., Hazelwood L., Byrnes G., Hollstein M., Zavadil J. (2014) Modelling mutational landscapes of human cancers in vitro Sci Rep.; 4482. PMID: 24670820

16. Giacomazzi J., Graudenz M.S., Osorio C.A., Koehler-Santos P., Palmero E.I., Zagonel-Oliveira M., Michelli R.A., Neto C.S., Fernandes G.C., Achatz M.I., Martel-Planche G., Soares F.A., Caleffi M., Goldim J.R., Hainaut P., Camey S.A., Ashton-Prolla P. (2014) Prevalence of the TP53 p.R337H Mutation in Breast Cancer Patients in Brazil PLoS ONE; 9(6):e99893. PMID: 24936644

17. Dai Y., Cros M.P., Pontoizeau C., Elena-Hermann B., Bonn G.K., Hainaut P. (2014) Downregulation of transcription factor E4F1 in hepatocarcinoma cells: HBV-dependent effects on autophagy, proliferation and metabolism Carcinogenesis; 35(3):635-650. PMID: 24163401

18. Ortiz-Cuaran S., Cox D., Villar S., Friesen M.D., Durand G., Chabrier A., Khuhaprema T., Sangrajrang S., Ognjanovic S., Groopman J.D., Hainaut P., Le Calvez-Kelm F. (2013) Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma Genes Chromosomes.Cancer; 52(10):912-919. PMID: 23836507

19. Sighoko D., Kamate B., Traore C., Malle B., Coulibaly B., Karidiatou A., Diallo C., Bah E., McCormack V., Muwonge R., Bourgeois D., Gormally E., Curado M.P., Bayo S., Hainaut P. (2013) Breast cancer in pre-menopausal women in West Africa: analysis of temporal trends and evaluation of risk factors associated with reproductive life Breast; 22(5):828-835. PMID: 23489760

20. Hollstein M., Moriya M., Grollman A.P., Olivier M. (2013) Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid Mutat.Res.; 753(1):41-49. PMID: 23422071

21. Shepherd F.A., Domerg C., Hainaut P., Janne P.A., Pignon J.P., Graziano S., Douillard J.Y., Brambilla E., Le Chevalier T., Seymour L., Bourredjem A., Le Teuff G., Pirker R., Filipits M., Rosell R., Kratzke R., Bandarchi B., Ma X., Capelletti M., Soria J.C., Tsao M.S. (2013) Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy Journal of clinical oncology; 31(17):2173-2181. PMID: 23630215

22. Lu X., Wontakal S.N., Kavi H., Kim B.J., Guzzardo P.M., Emelyanov A.V., Xu N., Hannon G.J., Zavadil J., Fyodorov D.V., Skoultchi A.I. (2013) Drosophila H1 regulates the genetic activity of heterochromatin by recruitment of Su(var)3-9 Science; 340(6128):78-81. PMID: 23559249

23. Ortiz-Cuaran S., Villar S., Gouas D., Ferro G., Plymoth A., Khuhaprema T., Kalalak A., Sangrajrang S., Friesen M.D., Groopman J.D., Hainaut P. (2013) Association between HBX status, aflatoxin-induced R249S TP53 mutation and risk of hepatocellular carcinoma in a case-control study from Thailand Cancer letters; 331(1):46-51. PMID: 23200676

24. Dichtel-Danjoy M.L., Ma D., Dourlen P., Chatelain G., Napoletano F., Robin M., Corbet M., Levet C., Hafsi H., Hainaut P., Ryoo H.D., Bourdon J.C., Mollereau B. (2013) Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation Cell Death.Differ.; 20(1):108-116. PMID: 22898807

25. Hainaut P., Olivier M., Wiman K.G. (2013) P53 in the Clinics ; -355p..

26. Hainaut P. (2013) TP53: coordinator of the processes that underlie the hallmarks of cancer ; 1-23.

27. Olivier M. (2013) TP53 somatic mutations: prognostic and predictive value in human cancers ; 127-146.

28. Langerod A., Olivier M., Borresen-Dale A.L. (2013) ; 147-165.

29. Fye H.K., Wright-Drakesmith C., Kramer H.B., Camey S., Nogueira da Costa A., Jeng A., Bah A., Kirk G.D., Sharif M.I., Ladep N.G., Okeke E., Hainaut P., Taylor-Robinson S.D., Kessler B.M., Mendy M.E. (2013) Protein profiling in hepatocellular carcinoma by label-free quantitative proteomics in two west African populations PLoS.One.; 8(7):e68381. PMID: 23935864

30. Hafsi H., Santos-Silva D., Courtois-Cox S., Hainaut P. (2013) Effects of Delta40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53 BMC.Cancer; 134. PMID: 23514281

31. Sagne C., Marcel V., Amadou A., Hainaut P., Olivier M., Hall J. (2013) A meta-analysis of cancer risk associated with the TP53 intron 3 duplication polymorphism (rs17878362): geographic and tumor-specific effects Cell Death.Dis; e492. PMID: 23412385

32. Gouas D.A., Villar S., Ortiz-Cuaran S., Legros P., Ferro G., Kirk G.D., Lesi O.A., Mendy M., Bah E., Friesen M.D., Groopman J., Chemin I., Hainaut P. (2012) TP53 R249S mutation, genetic variations in HBX and risk of hepatocellular carcinoma in The Gambia Carcinogenesis; 33(6):1219-1224. PMID: 22759751

33. Scoccianti C., Vesin A., Martel G., Olivier M., Brambilla E., Timsit J.F., Tavecchio L., Brambilla C., Field J.K., Hainaut P. (2012) Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort European respiratory journal; 40(1):177-184. PMID: 22267755

34. Gembarska A., Luciani F., Fedele C., Russell E.A., Dewaele M., Villar S., Zwolinska A., Haupt S., de Lange J., Yip D., Goydos J., Haigh J.J., Haupt Y., Larue L., Jochemsen A., Shi H., Moriceau G., Lo R.S., Ghanem G., Shackleton M., Bernal F., Marine J.C. (2012) MDM4 is a key therapeutic target in cutaneous melanoma Nature Medicine; 18(8):1239-1247. PMID: 22820643

35. de Fraipont F., Levallet G., Creveuil C., Bergot E., Beau-Faller M., Mounawar M., Richard N., Antoine M., Rouquette I., Favrot M.C., Debieuvre D., Braun D., Westeel V., Quoix E., Brambilla E., Hainaut P., Moro-Sibilot D., Morin F., Milleron B., Zalcman G. (2012) An apoptosis methylation prognostic signature for early lung cancer in the IFCT-0002 trial Clinical cancer research; 18(10):2976-2986. PMID: 22434665

36. Shang S., Plymoth A., Ge S., Feng Z., Rosen H.R., Sangrajrang S., Hainaut P., Marrero J.A., Beretta L. (2012) Identification of osteopontin as a novel marker for early hepatocellular carcinoma Hepatology; 55(2):483-490. PMID: 21953299

37. Blandino G., Deppert W., Hainaut P., Levine A., Lozano G., Olivier M., Rotter V., Wiman K., Oren M. (2012) Mutant p53 protein, master regulator of human malignancies: a report on the fifth Mutant p53 Workshop Cell death and differentiation; 19(1):180-183. PMID: 22095277

38. Hainaut P., Plymoth A. (2012) Cancer as a metabolic disease Current opinion in oncology; 24(1):56-57. PMID: 22143370

39. Abedi-Ardekani B., Dar N.A., Mir M.M., Zargar S.A., Lone M.M., Martel-Planche G., Villar S., Mounawar M., Saidi F., Malekzadeh R., Hainaut P. (2012) Epidermal growth factor receptor (EGFR) mutations and expression in squamous cell carcinoma of the esophagus in central Asia BMC.Cancer; 602. PMID: 23244191

40. Ognjanovic S., Martel G., Manivel C., Olivier M., Langer E., Hainaut P. (2012) Low Prevalence of TP53 Mutations and MDM2 Amplifications in Pediatric Rhabdomyosarcoma Sarcoma; 492086. PMID: 22550420

41. Villar S., Ortiz-Cuaran S., Abedi-Ardekani B., Gouas D., Nogueira da Costa A., Plymoth A., Khuhaprema T., Kalalak A., Sangrajrang S., Friesen M.D., Groopman J.D., Hainaut P. (2012) Aflatoxin-Induced TP53 R249S Mutation in HepatoCellular Carcinoma in Thailand: Association with Tumors Developing in the Absence of Liver Cirrhosis PLoS ONE; 7(6):e37707. PMID: 22675488

42. Fernandez-Cuesta L., Oakman C., Falagan-Lotsch P., Smoth K.S., Quinaux E., Buyse M., Dolci M.S., Azambuja E.D., Hainaut P., Dell'orto P., Larsimont D., Francis P.A., Crown J., Piccart-Gebhart M., Viale G., Leo A.D., Olivier M. (2012) Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy: results from the BIG 02-98 phase III trial Breast cancer research; 14(3):R70. PMID: 22551440

43. Balassiano K., Lima S., Jenab M., Overvad K., Tjonneland A., Boutron-Ruault M.C., Clavel-Chapelon F., Canzian F., Kaaks R., Boeing H., Meidtner K., Trichopoulou A., Laglou P., Vineis P., Panico S., Palli D., Grioni S., Tumino R., Lund E., Bueno-de-Mesquita H.B., Numans M.E., Peeters P.H., Ramon Quiros J., Sanchez M.A., Navarro C., Ardanaz E., Dorronsoro M., Hallmans G., Stenling R., Ehrnstrom R., Regner S., Allen N.E., Travis R.C., Khaw K.T., Offerhaus G.J., Sala N., Riboli E., Hainaut P., Scoazec J.Y., Sylla B.S., Gonzalez C.A., Herceg Z. (2011) Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Cancer letters; 311(1):85-95. PMID: 21831520

44. da Silva E.M., Achatz M.I., Martel-Planche G., Montagnini A.L., Olivier M., Prolla P.A., Hainaut P., Soares F.A. (2011) TP53 mutation p.R337H in gastric cancer tissues of a 12-year-old male child - evidence for chimerism involving a common mutant founder haplotype: case report BMC cancer; 11(1):449. PMID: 22004116

45. Krais A.M., Hautefeuille A.H., Cros M.P., Krutovskikh V., Tournier J.M., Birembaut P., Thepot A., Paliwal A., Herceg Z., Boffetta P., Brennan P., Hainaut P.L. (2011) CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression Carcinogenesis; 32(9):1388-1395. PMID: 21586512

46. Hafsi H., Hainaut P. (2011) Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence Antioxidants & redox signaling; 15(6):1655-1667. PMID: 21194382

47. Moore H.M., Kelly A.B., Jewell S.D., McShane L.M., Clark D.P., Greenspan R., Hayes D.F., Hainaut P., Kim P., Mansfield E., Potapova O., Riegman P., Rubinstein Y., Seijo E., Somiari S., Watson P., Weier H.U., Zhu C., Vaught J. (2011) Biospecimen Reporting for Improved Study Quality (BRISQ) J Proteome Res; 10(8):3429-3438. PMID: 21574648

48. Beau-Faller M., Degeorges A., Rolland E., Mounawar M., Antoine M., Poulot V., Mauguen A., Barbu V., Coulet F., Pretet J.L., Bieche I., Blons H., Boyer J.C., Buisine M.P., de Fraipont F., Lizard S., Olschwang S., Saulnier P., Prunier-Mirebeau D., Richard N., Danel C., Brambilla E., Chouaid C., Zalcman G., Hainaut P., Michiels S., Cadranel J. (2011) Cross-Validation Study for Epidermal Growth Factor Receptor and KRAS Mutation Detection in 74 Blinded Non-small Cell Lung Carcinoma Samples: A Total of 5550 Exons Sequenced by 15 Molecular French Laboratories (Evaluation of the EGFR Mutation Status for the Administration of EGFR-TKIs in Non-Small Cell Lung Carcinoma [ERMETIC] Project-Part 1) J Thorac Oncol; 6(6):1006-1015. PMID: 21532509

49. Nogueira da Costa A., Mijal R.S., Keen J.N., Findlay J.B., Wild C.P. (2011) Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol Proteomics; 11(10):1903-1914. PMID: 21462343

50. Lambert M.P., Paliwal A., Vaissiere T., Chemin I., Zoulim F., Tommasino M., Hainaut P., Sylla B., Scoazec J.Y., Tost J., Herceg Z. (2011) Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake J Hepatol; 54(4):705-715. PMID: 21146512

51. Brennan P., Hainaut P., Boffetta P. (2011) Genetics of lung-cancer susceptibility Lancet oncology; 12(4):399-408. PMID: 20951091

52. Fernandez-Cuesta L., Anaganti S., Hainaut P., Olivier M. (2011) p53 status influences response to tamoxifen but not to fulvestrant in breast cancer cell lines International journal of cancer; 128(8):1813-1821. PMID: 20549698

53. Moore H.M., Kelly A.B., Jewell S.D., McShane L.M., Clark D.P., Greenspan R., Hayes D.F., Hainaut P., Kim P., Mansfield E.A., Potapova O., Riegman P., Rubinstein Y., Seijo E., Somiari S., Watson P., Weier H.U., Zhu C., Vaught J. (2011) Biospecimen reporting for improved study quality (BRISQ) Cancer Cytopathol; 119(2):92-102. PMID: 21433001

54. Moore H.M., Kelly A., Jewell S.D., McShane L.M., Clark D.P., Greenspan R., Hainaut P., Hayes D.F., Kim P., Mansfield E., Potapova O., Riegman P., Rubinstein Y., Seijo E., Somiari S., Watson P., Weier H.U., Zhu C., Vaught J. (2011) Biospecimen Reporting for Improved Study Quality Biopreserv Biobank; 9(1):57-70. PMID: 21826252

55. Hafsi H., Hainaut P. (2011) Pharmacological rescue of p53 in cancer cells: The soloist meets the PRIMA donna Cell Cycle; 10(6):875-876. PMID: 21358263

56. Marcel V., Tran P.L., Sagne C., Martel-Planche G., Vaslin L., Teulade-Fichou M.P., Hall J., Mergny J.L., Hainaut P., Van Dyck E. (2011) G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms Carcinogenesis; 32(3):271-278. PMID: 21112961

57. Marcel V., Olivier M., Mollereau B., Hainaut P., Bourdon J.C. (2011) First International p53 Isoforms Meeting: 'p53 isoforms through evolution: from identification to biological function' Cell death and differentiation; 18(3):563-564. PMID: 21151028

58. Umoh N.J., Lesi O.A., Mendy M., Bah E., Akano A., Whittle H., Hainaut P., Kirk G.D. (2011) Aetiological differences in demographical, clinical and pathological characteristics of hepatocellular carcinoma in The Gambia Liver International; 31(2):215-221. PMID: 21143369

59. Franceschi S., Lise M., Trepo C., Berthillon P., Chuang S.C., Nieters A., Travis R.C., Vermeulen R., Overvad K., Tjonneland A., Olsen A., Bergmann M.M., Boeing H., Kaaks R., Becker N., Trichopoulou A., Lagiou P., Bamia C., Palli D., Sieri S., Panico S., Tumino R., Sacerdote C., Bueno-de-Mesquita B., Peeters P.H., Rodriguez L., Barroso L.L., Dorronsoro M., Sanchez M.J., Navarro C., Barricarte A., Regner S., Borgquist S., Melin B., Hallmans G., Khaw K.T., Wareham N., Rinaldi S., Hainaut P., Riboli E., Vineis P. (2011) Infection with hepatitis B and C viruses and risk of lymphoid malignancies in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cancer epidemiology, biomarkers & prevention; 20(1):208-214. PMID: 21098651

60. Fernandez-Cuesta L., Anaganti S., Hainaut P., Olivier M. (2011) Estrogen levels act as a rheostat on p53 levels and modulate p53-dependent responses in breast cancer cell lines Breast cancer research and treatment; 125(1):35-42. PMID: 20221692

61. Goldstein I., Marcel V., Olivier M., Oren M., Rotter V., Hainaut P. (2011) Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies Cancer Gene Therapy; 18(1):2-11. PMID: 20966976

62. Anaganti S., Fernandez-Cuesta L., Langerod A., Hainaut P., Olivier M. (2011) p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines Cancer letters; 300(2):215-224. PMID: 21071137

63. Olivier M., Taniere P. (2011) Somatic mutations in cancer prognosis and prediction: lessons from TP53 and EGFR genes Current opinion in oncology; 23(1):88-92. PMID: 21045690

64. Pfeifer G.P., Hainaut P. (2011) Next-generation sequencing: emerging lessons on the origins of human cancer Current opinion in oncology; 23(1):62-68. PMID: 21119514

65. Plymoth A., Hainaut P. (2011) Proteomics beyond proteomics: toward clinical applications Current opinion in oncology; 23(1):77-82. PMID: 21107258

66. Hainaut P., Plymoth A. (2011) Biomarkers in cancer research and treatment: promises and challenges Current opinion in oncology; 23(1):61. PMID: 21321519

67. Galy O., Chemin I., Le Roux E., Villar S., Le Calvez-Kelm F., Lereau M., Gouas D., Vieco B., Suarez I., Navas M.C., Chevallier M., Norder H., Srivatanakul P., Karalak A., Sangrajrang S., Trepo C., Hainaut P. (2011) Mutations in TP53 and CTNNB1 in Relation to Hepatitis B and C Infections in Hepatocellular Carcinomas from Thailand Hepat Res Treat; doi:10.1155/2011/697. PMID: 21760996

68. Thepot A., Desanlis A., Venet E., Thivillier L., Justin V., Morel A.P., Defraipont F., Till M., Krutovskikh V., Tommasino M., Damour O., Hainaut P. (2011) Assessment of transformed properties in vitro and of tumorigenicity in vivo in primary keratinocytes cultured for epidermal sheet transplantation J Skin Cancer; 936546. PMID: 21188234

69. Hewitt R., Hainaut P. (2011) Biobanking in a fast moving world: an international perspective J Natl Cancer Inst Monogr; 2011(42):50-51. PMID: 21672898

70. Abedi-Ardekani B., Gouas D., Villar S., Sotoudeh M., Hainaut P. (2011) TP53 Mutations and HBX Status Analysis in Hepatocellular Carcinomas from Iran: Evidence for Lack of Association between HBV Genotype D and TP53 R249S Mutations Hepat Res Treat; 475965. PMID: 21869931

71. Navas M.C., Suarez I., Carreno A., Uribe D., Rios W.A., Cortes-Mancera F., Martel G., Vieco B., Lozano D., Jimenez C., Gouas D., Osorio G., Hoyos S., Restrepo J.C., Correa G., Jaramillo S., Lopez R., Bravo L.E., Arbelaez M.P., Scoazec J.Y., Abedi-Ardekani B., Santella R.M., Chemin I., Hainaut P. (2011) Hepatitis B and Hepatitis C Infection Biomarkers and TP53 Mutations in Hepatocellular Carcinomas from Colombia Hepat Res Treat; 582945. PMID: 22114738

72. Hainaut P., Vozar B., Rinaldi S., Riboli E., Caboux E. (2011) The European Prospective Investigation into Cancer and Nutrition biobank Methods in Molecular Biology; 179-191. PMID: 20949388

73. Abedi-Ardekani B., Kamangar F., Sotoudeh M., Villar S., Islami F., Aghcheli K., Nasrollahzadeh D., Taghavi N., Dawsey S.M., Abnet C.C., Hewitt S.M., Fahimi S., Saidi F., Brennan P., Boffetta P., Malekzadeh R., Hainaut P. (2011) Extremely high tp53 mutation load in esophageal squamous cell carcinoma in golestan province, iran PLoS ONE; 6(12):e29488. PMID: 22216294

74. Sighoko D., Curado M.P., Bourgeois D., Mendy M., Hainaut P., Bah E. (2011) Increase in female liver cancer in the gambia, west Africa: evidence from 19 years of population-based cancer registration (1988-2006) PLoS ONE; 6(4):e18415. PMID: 21490972