Research Groups

Section of Molecular Pathology

Previous Publications - All Publications 2016-2012

1. Wang Q., Satomi K., Oh J. E., Hutter B., Brors B., Diessl N., Liu H. K., Wolf S., Wiestler O., Kleihues P., Koelsch B., Kindler-Rohrborn A., Ohgaki H. (2016) Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea Am J Pathol; 186(10):2569-76. PMID: 27658714

2. Gramatzki D., Dehler S., Rushing E. J., Zaugg K., Hofer S., Yonekawa Y., Bertalanffy H., Valavanis A., Korol D., Rohrmann S., Pless M., Oberle J., Roth P., Ohgaki H., Weller M. (2016) Glioblastoma in the Canton of Zurich, Switzerland revisited: 2005 to 2009 Cancer; 122(14):2206-15. PMID: 27088883

3. Oh J. E., Ohta T., Nonoguchi N., Satomi K., Capper D., Pierscianek D., Sure U., Vital A., Paulus W., Mittelbronn M., Antonelli M., Kleihues P., Giangaspero F., Ohgaki H. (2016) Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma Brain Pathol; 26(4):517-22. PMID: 26443480

4. Zhao F., Ohgaki H., Xu L., Giangaspero F., Li C., Li P., Yang Z., Wang B., Wang X., Wang Z., Ai L., Zhang J., Luo L., Liu P. (2016) Molecular subgroups of adult medulloblastoma: a long-term single-institution study Neuro Oncol; 18(7):982-90. PMID: 27106407

5. Louis D. N., Perry A., Reifenberger G., von Deimling A., Figarella-Branger D., Cavenee W. K., Ohgaki H., Wiestler O. D., Kleihues P., Ellison D. W. (2016) The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary Acta Neuropathol; 131(6):803-20. PMID: 27157931

6. Stewart B. W., Bray F., Forman D., Ohgaki H., Straif K., Ullrich A., Wild C. P. (2016) Cancer prevention as part of precision medicine: 'plenty to be done' Carcinogenesis; 37(1):2-9. PMID: 26590901

7. Parroche P., Roblot G., Le Calvez-Kelm F., Tout I., Marotel M., Malfroy M., Durand G., McKay J., Ainouze M., Carreira C., Allatif O., Traverse-Glehen A., Mendiola M., Pozo-Kreilinger J. J., Caux C., Tommasino M., Goutagny N., Hasan U. A. (2016) TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression Oncogenesis; 5(7):e244. PMID: 27454079

8. Walsh K. M., Ohgaki H., Wrensch M. R. (2016) Epidemiology Handb Clin Neurol; 3-18. PMID: 26948345

9. Oh J.E., Ohta T., Satomi K., Foll M., Durand G., McKay J., Le Calvez-Kelm F., Mittelbronn M., Brokinkel B., Paulus W., Ohgaki H. (2015) Alterations in the NF2/LATS1/LATS2/YAP Pathway in Schwannomas J Neuropathol. Exp. Neurol; 74(10):952-959. PMID: 26360373

10. Baumgarten P., Harter P.N., Tonjes M., Capper D., Blank A.E., Sahm F., von Deimling A., Kolluru V., Schwamb B., Rabenhorst U., Starzetz T., Kogel D., Rieker R.J., Plate K.H., Ohgaki H., Radlwimmer B., Zornig M., Mittelbronn M. (2014) Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity Neuropathol. Appl. Neurobiol; 40(2):205-216.

11. Corbex M., Bouzbid S., Traverse-Glehen A., Aouras H., McKay-Chopin S., Carreira C., Lankar A., Tommasino M., Gheit T. (2014) Prevalence of papillomaviruses, polyomaviruses, and herpesviruses in triple-negative and inflammatory breast tumors from algeria compared with other types of breast cancer tumors PLoS ONE; 9(12):e114559.

12. Fiaschetti G., Abela L., Nonoguchi N., Dubuc A.M., Remke M., Boro A., Grunder E., Siler U., Ohgaki H., Taylor M.D., Baumgartner M., Shalaby T., Grotzer M.A. (2014) Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma Br J Cancer; 110(3):636-647.

13. Gheit T., Abedi-Ardekani B., Carreira C., Missad C.G., Tommasino M., Torrente M.C. (2014) Comprehensive analysis of HPV expression in laryngeal squamous cell carcinoma J Med Virol; 86(4):642-646.

14. Kim Y.H., Ohta T., Oh J.E., Le Calvez-Kelm F., McKay J., Voegele C., Durand G., Mittelbronn M., Kleihues P., Paulus W., Ohgaki H. (2014) TP53, MSH4, and LATS1 Germline Mutations in a Family with Clustering of Nervous System Tumors Am J Pathol; 184(9):2374-2381.

15. Louis D.N., Perry A., Burger P., Ellison D.W., Reifenberger G., von Deimling A., Aldape K., Brat D., Collins V.P., Eberhart C., Figarella-Branger D., Fuller G.N., Giangaspero F., Giannini C., Hawkins C., Kleihues P., Korshunov A., Kros J.M., Beatriz Lopes M., Ng H.K., Ohgaki H., Paulus W., Pietsch T., Rosenblum M., Rushing E., Soylemezoglu F., Wiestler O., Wesseling P. (2014) International society of neuropathology-haarlem consensus guidelines for nervous system tumor classification and grading Brain Pathol; 24(5):429-435.

16. Ohgaki H., Burger P., Kleihues P. (2014) Definition of primary and secondary glioblastoma--response Clin Cancer Res; 20(7):2013.

17. Ohta T., Kim Y.H., Oh J.E., Satomi K., Nonoguchi N., Keyvani K., Pierscianek D., Sure U., Mittelbronn M., Paulus W., Vital A., Yokoo H., McDonald K., Kleihues P., Nazaret N., Barbet F., Lachuer J., Ohgaki H. (2014) Alterations of the RRAS and ERCC1 Genes at 19q13 in Gemistocytic Astrocytomas J Neuropathol Exp Neurol; 73(10):908-915.

18. Peng C., Deng Q., Li Z., Xiong C., Li C., Zheng F. (2014) Risk-Association of DNMT1 Gene Polymorphisms with Coronary Artery Disease in Chinese Han Population Int J Mol Sci; 15(12):22694-22705.

19. Suzuki A., Nobusawa S., Natsume A., Suzuki H., Kim Y.H., Yokoo H., Nagaishi M., Ikota H., Nakazawa T., Wakabayashi T., Ohgaki H., Nakazato Y. (2014) Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas J Neurooncol; 120(2):283-291.

20. Xu Q.F., Pan Y.W., Li L.C., Zhou Z., Huang Q.L., Pang J.C., Zhu X.P., Ren Y., Yang H., Ohgaki H., Lv S.Q. (2014) MiR-22 is Frequently Downregulated in Medulloblastomas and Inhibits Cell Proliferation via the Novel Target PAPST1 Brain Pathol; 24(6):568-583.

21. Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Nonoguchi N., Pierscianek D., Kim Y.H., Mariani L., Vital A., Perry A., Ohgaki H. (2013) PDGFRA gain in low-grade diffuse gliomas J Neuropathol Exp Neurol; 72(1):61-66.

22. Nonoguchi N., Ohta T., Oh J.E., Kim Y.H., Kleihues P., Ohgaki H. (2013) TERT promoter mutations in primary and secondary glioblastomas Acta Neuropathol; 126(6):931-937.

23. Ohgaki H. (2013) Contribution of Molecular Biology to the Classification of Low-Grade Diffuse Glioma ; 61-72.

24. Ohgaki H., Kleihues P. (2013) The definition of primary and secondary glioblastoma Clin Cancer Res; 19(4):764-772.

25. Pierscianek D., Kim Y.H., Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Wrede K., Nakazato Y., Tanaka Y., Mariani L., Vital A., Sure U., Ohgaki H. (2013) MET gain in diffuse astrocytomas is associated with poorer outcome Brain Pathol; 23(1):13-18.

26. Sasaki A., Yokoo H., Tanaka Y., Homma T., Nakazato Y., Ohgaki H. (2013) Characterization of microglia/macrophages in gliomas developed in S-100beta-v-erbB transgenic rats Neuropathology; 33(5):505-514.

27. Wozniak M.B., Le Calvez-Kelm F., Abedi-Ardekani B., Byrnes G., Durand G., Carreira C., Michelon J., Janout V., Holcatova I., Foretova L., Brisuda A., Lesueur F., McKay J., Brennan P., Scelo G. (2013) Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States PLoS. One; 8(3):e57886.

28. Badiali M., Gleize V., Paris S., Moi L., Elhouadani S., Arcella A., Morace R., Antonelli M., Buttarelli F.R., Figarella-Branger D., Kim Y.H., Ohgaki H., Mokhtari K., Sanson M., Giangaspero F. (2012) KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults Brain Pathol; 22(6):841-847.

29. Kim Y.H., Nonoguchi N., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Mariani L., Giangaspero F., Tanaka Y., Nakazato Y., Vital A., Mittelbronn M., Perry A., Ohgaki H. (2012) Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss Brain Pathol; 22(6):834-840.

30. Lv S.Q., Kim Y.H., Giulio F., Shalaby T., Nobusawa S., Yang H., Zhou Z., Grotzer M., Ohgaki H. (2012) Genetic Alterations in MicroRNAs in Medulloblastomas Brain Pathol; 22(2):230-239.

31. Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Pierscianek D., Kim Y.H., Mariani L., Vital A., Ohgaki H. (2012) DMBT1 Homozygous Deletion in Diffuse Astrocytomas Is Associated With Unfavorable Clinical Outcome J Neuropathol Exp Neurol; 71(8):702-707.

32. Nagaishi M., Kim Y.H., Mittelbronn M., Giangaspero F., Paulus W., Brokinkel B., Vital A., Tanaka Y., Nakazato Y., Legras-Lachuer C., Lachuer J., Ohgaki H. (2012) Amplification of the STOML3, FREM2, and LHFP Genes Is Associated with Mesenchymal Differentiation in Gliosarcoma Am J Pathol; 180(5):1816-1823.

33. Nagaishi M., Paulus W., Brokinkel B., Vital A., Tanaka Y., Nakazato Y., Giangaspero F., Ohgaki H. (2012) Transcriptional factors for epithelial-mesenchymal transition are associated with mesenchymal differentiation in gliosarcoma Brain Pathol; 22(5):670-676.