Research Groups

Section of Molecular Pathology

Previous Publications - All Publications 2015-2011

1. Suzuki A., Nobusawa S., Natsume A., Suzuki H., Kim Y.H., Yokoo H., Nagaishi M., Ikota H., Nakazawa T., Wakabayashi T., Ohgaki H., Nakazato Y. (2014) Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas J Neurooncol.; 120(2):283-291. PMID: 25085214

2. Xu Q.F., Pan Y.W., Li L.C., Zhou Z., Huang Q.L., Pang J.C., Zhu X.P., Ren Y., Yang H., Ohgaki H., Lv S.Q. (2014) MiR-22 is Frequently Downregulated in Medulloblastomas and Inhibits Cell Proliferation via the Novel Target PAPST1 Brain pathology; 24(6):568-583. PMID: 24576181

3. Ohta T., Kim Y.H., Oh J.E., Satomi K., Nonoguchi N., Keyvani K., Pierscianek D., Sure U., Mittelbronn M., Paulus W., Vital A., Yokoo H., McDonald K., Kleihues P., Nazaret N., Barbet F., Lachuer J., Ohgaki H. (2014) Alterations of the RRAS and ERCC1 Genes at 19q13 in Gemistocytic Astrocytomas Journal of neuropathology and experimental neurology; 73(10):908-915. PMID: 25192052

4. Louis D.N., Perry A., Burger P., Ellison D.W., Reifenberger G., von Deimling A., Aldape K., Brat D., Collins V.P., Eberhart C., Figarella-Branger D., Fuller G.N., Giangaspero F., Giannini C., Hawkins C., Kleihues P., Korshunov A., Kros J.M., Beatriz Lopes M., Ng H.K., Ohgaki H., Paulus W., Pietsch T., Rosenblum M., Rushing E., Soylemezoglu F., Wiestler O., Wesseling P. (2014) International society of neuropathology-haarlem consensus guidelines for nervous system tumor classification and grading Brain pathology; 24(5):429-435. PMID: 24990071

5. Kim Y.H., Ohta T., Oh J.E., Le Calvez-Kelm F., McKay J., Voegele C., Durand G., Mittelbronn M., Kleihues P., Paulus W., Ohgaki H. (2014) TP53, MSH4, and LATS1 Germline Mutations in a Family with Clustering of Nervous System Tumors American journal of pathology; 184(9):2374-2381. PMID: 25041856

6. Gheit T., Abedi-Ardekani B., Carreira C., Missad C.G., Tommasino M., Torrente M.C. (2014) Comprehensive analysis of HPV expression in laryngeal squamous cell carcinoma Journal of medical virology; 86(4):642-646. PMID: 24374907

7. Ohgaki H., Burger P., Kleihues P. (2014) Definition of primary and secondary glioblastoma--response Clinical cancer research; 20(7):2013. PMID: 24557936

8. Baumgarten P., Harter P.N., Tonjes M., Capper D., Blank A.E., Sahm F., von Deimling A., Kolluru V., Schwamb B., Rabenhorst U., Starzetz T., Kogel D., Rieker R.J., Plate K.H., Ohgaki H., Radlwimmer B., Zornig M., Mittelbronn M. (2014) Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity Neuropathol.Appl.Neurobiol.; 40(2):205-216. PMID: 24117486

9. Fiaschetti G., Abela L., Nonoguchi N., Dubuc A.M., Remke M., Boro A., Grunder E., Siler U., Ohgaki H., Taylor M.D., Baumgartner M., Shalaby T., Grotzer M.A. (2014) Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma British journal of cancer; 110(3):636-647. PMID: 24346283

10. Corbex M., Bouzbid S., Traverse-Glehen A., Aouras H., McKay-Chopin S., Carreira C., Lankar A., Tommasino M., Gheit T. (2014) Prevalence of papillomaviruses, polyomaviruses, and herpesviruses in triple-negative and inflammatory breast tumors from algeria compared with other types of breast cancer tumors PLoS ONE; 9(12):e114559. PMID: 25478862

11. Peng C., Deng Q., Li Z., Xiong C., Li C., Zheng F. (2014) Risk-Association of DNMT1 Gene Polymorphisms with Coronary Artery Disease in Chinese Han Population Int J Mol Sci; 15(12):22694-22705. PMID: 25493477

12. Nonoguchi N., Ohta T., Oh J.E., Kim Y.H., Kleihues P., Ohgaki H. (2013) TERT promoter mutations in primary and secondary glioblastomas Acta Neuropathol.; 126(6):931-937. PMID: 23955565

13. Sasaki A., Yokoo H., Tanaka Y., Homma T., Nakazato Y., Ohgaki H. (2013) Characterization of microglia/macrophages in gliomas developed in S-100beta-v-erbB transgenic rats Neuropathology.; 33(5):505-514. PMID: 23331472

14. Ohgaki H., Kleihues P. (2013) The definition of primary and secondary glioblastoma Clin Cancer Res.; 19(4):764-772. PMID: 23209033

15. Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Nonoguchi N., Pierscianek D., Kim Y.H., Mariani L., Vital A., Perry A., Ohgaki H. (2013) PDGFRA gain in low-grade diffuse gliomas Journal of neuropathology and experimental neurology; 72(1):61-66. PMID: 23242283

16. Pierscianek D., Kim Y.H., Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Wrede K., Nakazato Y., Tanaka Y., Mariani L., Vital A., Sure U., Ohgaki H. (2013) MET gain in diffuse astrocytomas is associated with poorer outcome Brain pathology; 23(1):13-18. PMID: 22672415

17. Wozniak M.B., Le Calvez-Kelm F., Abedi-Ardekani B., Byrnes G., Durand G., Carreira C., Michelon J., Janout V., Holcatova I., Foretova L., Brisuda A., Lesueur F., McKay J., Brennan P., Scelo G. (2013) Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States PLoS.One.; 8(3):e57886. PMID: 23526956

18. Ohgaki H. (2013) Contribution of Molecular Biology to the Classification of Low-Grade Diffuse Glioma ; 61-72.

19. Badiali M., Gleize V., Paris S., Moi L., Elhouadani S., Arcella A., Morace R., Antonelli M., Buttarelli F.R., Figarella-Branger D., Kim Y.H., Ohgaki H., Mokhtari K., Sanson M., Giangaspero F. (2012) KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults Brain pathology; 22(6):841-847. PMID: 22591444

20. Kim Y.H., Nonoguchi N., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Mariani L., Giangaspero F., Tanaka Y., Nakazato Y., Vital A., Mittelbronn M., Perry A., Ohgaki H. (2012) Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss Brain pathology; 22(6):834-840. PMID: 22568401

21. Nagaishi M., Paulus W., Brokinkel B., Vital A., Tanaka Y., Nakazato Y., Giangaspero F., Ohgaki H. (2012) Transcriptional factors for epithelial-mesenchymal transition are associated with mesenchymal differentiation in gliosarcoma Brain pathology; 22(5):670-676. PMID: 22288519

22. Motomura K., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nakazato Y., Tanaka Y., Pierscianek D., Kim Y.H., Mariani L., Vital A., Ohgaki H. (2012) DMBT1 Homozygous Deletion in Diffuse Astrocytomas Is Associated With Unfavorable Clinical Outcome Journal of neuropathology and experimental neurology; 71(8):702-707. PMID: 22805772

23. Nagaishi M., Kim Y.H., Mittelbronn M., Giangaspero F., Paulus W., Brokinkel B., Vital A., Tanaka Y., Nakazato Y., Legras-Lachuer C., Lachuer J., Ohgaki H. (2012) Amplification of the STOML3, FREM2, and LHFP Genes Is Associated with Mesenchymal Differentiation in Gliosarcoma American journal of pathology; 180(5):1816-1823. PMID: 22538188

24. Lv S.Q., Kim Y.H., Giulio F., Shalaby T., Nobusawa S., Yang H., Zhou Z., Grotzer M., Ohgaki H. (2012) Genetic Alterations in MicroRNAs in Medulloblastomas Brain pathology; 22(2):230-239. PMID: 21793975

25. Nobusawa S., Stawski R., Kim Y.H., Nakazato Y., Ohgaki H. (2011) Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study Neuropathology; 31(6):583-588. PMID: 21382095

26. Kim Y.H., Lachuer J., Mittelbronn M., Paulus W., Brokinkel B., Keyvani K., Sure U., Wrede K., Nobusawa S., Nakazato Y., Tanaka Y., Vital A., Mariani L., Ohgaki H. (2011) Alterations in the RB1 Pathway in Low-grade Diffuse Gliomas Lacking Common Genetic Alterations Brain pathology; 21(6):645-651. PMID: 21470325

27. Grunder E., D'Ambrosio R., Fiaschetti G., Abela L., Arcaro A., Zuzak T., Ohgaki H., Lv S.Q., Shalaby T., Grotzer M. (2011) MicroRNA-21 suppression impedes medulloblastoma cell migration European journal of cancer; 47(16):2479-2490. PMID: 21775132

28. Kim Y.H., Pierscianek D., Mittelbronn M., Vital A., Mariani L., Hasselblatt M., Ohgaki H. (2011) TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations Journal of clinical pathology; 64(10):850-852. PMID: 21690245

29. Ohgaki H., Kleihues P. (2011) Genetic profile of astrocytic and oligodendroglial gliomas Brain Tumor Pathol; 28(3):177-183. PMID: 21442241

30. Fiaschetti G., Castelletti D., Zoller S., Schramm A., Schroeder C., Nagaishi M., Stearns D., Mittelbronn M., Eggert A., Westermann F., Ohgaki H., Shalaby T., Pruschy M., Arcaro A., Grotzer M.A. (2011) Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma Oncogene; 30(25):2823-2835. PMID: 21317922

31. Chargari C., Comperat E., Magne N., Vedrine L., Houlgatte A., Egevad L., Camparo P. (2011) Prostate needle biopsy examination by means of virtual microscopy Pathol Res Pract; 207(6):366-369. PMID: 21570778

32. Toedt G., Barbus S., Wolter M., Felsberg J., Tews B., Blond F., Sabel M.C., Hofmann S., Becker N., Hartmann C., Ohgaki H., von Deimling A., Wiestler O.D., Hahn M., Lichter P., Reifenberger G., Radlwimmer B. (2011) Molecular signatures classify astrocytic gliomas by IDH1 mutation status International journal of cancer; 128(5):1095-1103. PMID: 20473936