Who's Who

James Mckay

Group Head

Genetic Cancer Susceptibility Group


Specialty:

Genetic susceptibility to human diseases, with a particular focus on genetic susceptibilty to tobacco-related cancers

Academic Degrees

YearDegreeMajorInstitutionTownCountry
2003PhDMolecular GeneticsUniversity of Tasmania/IARCHobart/LyonAustralia/France
1996Bsc (first class honors)Molecular BiologyUniversity of TasmaniaHobartAustralia/


Current Research Projects

  • Development of Next generation sequencing at IARC
    Le Calvez-Kelm F, McKay JD

  • Expansion of genome wide association study approaches to identify cancer susceptibility alleles (head and neck cancers and Hodgkin’s lymphoma)
    McKay JD + (GEP, ICE and external collaborators)

  • Identification of novel lung cancer genetic susceptibility loci using two hit gene mapping
    McKay JD + (GEP, BST)


Selected Publications

Johansson M, Roberts A, Chen D, Li Y, Delahaye-Sourdeix M, Aswani N, Greenwood MA, Benhamou S, Lagiou P, Holcátová I, Richiardi L, Kjaerheim K, Agudo A, Castellsagué X, Macfarlane TV, Barzan L, Canova C, Thakker NS, Conway DI, Znaor A, Healy CM, Ahrens W, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Fabianova E, Mates IN, Bencko V, Foretova L, Janout V, Curado MP, Koifman S, Menezes A, Wünsch-Filho V, Neto JE, Boffetta P, Franceschi S, Herrero R, Fernandez Garrote L, Talamini R, Boccia S, Galan P, Vatten L, Thomson P, Zelenika D, Lathrop M, Byrnes G, Cunningham H, Brennan P, Wakefield J, Mckay JD (2012 ) in press Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4 - the AdAPT method. PLoS One

Urayama KY, Jarrett RF, Hjalgrim H, Diepstra A, Kamatani Y, Chabrier A, Gaborieau V, Boland A, Nieters A, Becker N, Foretova L, Benavente Y, Maynadié M, Staines A, Shield L, Lake A, Montgomery D, Taylor M, Ekström Smedby K, Amini R-M, Adami H-O, Glimelius B, Feenstra B, Nolte IM, Visser L, van Imhoff GW, Lightfoot T, Cocco P, Kiemeney L, Vermeulen SH, Holcatova I, Vatten L, Macfarlane GJ,Thomson P, Conway DI, Benhamou S, Agudo A, Healy CM, Overvad K, Tjønneland A, Melin B, Canzian F, Khaw K-T, Travis RC, Peeters PHM, González CA, Quirós JR, Sánchez M-J, Huerta J-M, Ardanaz E, Dorronsoro M, Clavel-Chapelon F, Bas Bueno-de-Mesquita H, Riboli E, Roman E, Boffetta P, de Sanjosé S, Zelenika D, Melbye M, van den Berg A, Brennan P, Lathrop M, McKay JD (2012) Genome-wide Association Study of Classical Hodgkin Lymphoma and EBV Status-defined. J Natl Cancer Inst., 104(3) : 240-53

McKay JD, Truong T, Gaborieau V, Chabrier A, Shu-chun Chuang, Byrnes G, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Bucur A, Bencko V, Holcatova I, Janout V, Foretova L, Lagiou P, Trichopoulos D, Benhamou S, Bouchardy C, Ahrens W, Merletti F, Richiardi L, Talamini R, Barzan L, Kjaerheim K, Macfarlane GJ, Macfarlane TV, Simonato L, Canova C, Agudo A, Castellsagué X, Lowry R, Conway DI, McKinney PA, Healy CM, Toner ME, Znaor A, Curado MP, Koifman S, Menezes A, Wünsch-Filho V, Eluf Neto J, Fernandez L, Boccia S, Cadoni G, Arzani D, Olshan AF, Weissler MC, Funkhouser WK, Jingchun L, Lubiński J, Trubicka J, Lener M, Oszutowska D, Schwartz SM, Chen C, Fish S, Doody DR, Muscat JE, Lazarus P, Gallagher CJ, Chang SC, Zhang Z-F, Wei W, Sturgis EM, Wang L-E, Franceschi S, Herrero R, Kelsey KT, McClean MD, Marsit CJ, Nelson HH, Romkes M, Buch S, Nukui T, Zhong S, Lacko M, Manni JJ, Peters WHM, Hung RJ, McLaughlin J, Vatten L, Njølstad I, Goodman GE, Field JK, Liloglou T, Vineis P, Clavel-Chapelon F, Palli D, Tumino R, Krogh V, Panico S, González CA, Quirós JR, Martínez C, Navarro C, Ardanaz E, Larrañaga N, Khaw K-T, Key T, Bueno-de-Mesquita HB, Peeters PHM, Trichopoulou A, Linseisen J, Boeing H, Hallmans G, Overvad K, Tjønneland A, Kumle M, Riboli E, Välk K, Vooder T, Metspalu A, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Blanche H, Gut IG, Galan P, Heath S, Hashibe M, Hayes RB, Boffetta P, Lathrop M, Brennan P. (2011) A genome-wide association study of upper aerodigestive tract cancers. conducted within the INHANCE consortium PLoS Genet., 7(3) : e1001333

Hung RJ*, McKay JD* (*equally contributing authors), Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field J, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Shorpen F, Bratt Elvestad M, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita H, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P Trichopoulos D, Holcátová I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway D, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P. (2008) A genome-wide association study identifies a susceptibility locus for lung cancer encompassing nicotinic acetylcholine receptor subunit genes on 15q25 Nature, 452(7187) : 633-7

McKay JD, Hung RJ, Gaborieau V, Boffetta P, Chabrier A, Byrnes G, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, McLaughlin J, Shepherd F, Montpetit A, Narod S, Krokan HE, Skorpen F, Elvestad MB, Vatten L, Njølstad I, Axelsson T, Chen C, Goodman G, Barnett M, Loomis MM, Lubiñski J, Matyjasik J, Lener M, Oszutowska D, Field J, Liloglou T, Xinarianos G, Cassidy A; EPIC Study, Vineis P, Clavel-Chapelon F, Palli D, Tumino R, Krogh V, Panico S, González CA, Ramón Quirós J, Martínez C, Navarro C, Ardanaz E, Larrañaga N, Kham KT, Key T, Bueno-de-Mesquita HB, Peeters PH, Trichopoulou A, Linseisen J, Boeing H, Hallmans G, Overvad K, Tjønneland A, Kumle M, Riboli E, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P. (2008) Lung cancer susceptibility locus at 5p15.33. Nat. Genet., 40(12) : 1404-6

Scientific Societies Membership

American Association for Cancer Research
American Society of Human Genetics

Prizes, Honours

2005 - CJ Martin fellow
2004 - IARC fellowship, International Agency for Research on Cancer, France
2002 - Winner: Young Tasmanian of the Year: Science and Technology
1999-2001 - Recipient of Special Training Award from International Agency for Research on Cancer, France
1999 - Recipient of the Godard Sapin-Jaloustre Foundation Scholarship for studies in France