Who's Who

Hector Hernandez Vargas

Scientist

Epigenetics Group


Specialty:

Mechanisms of carcinogenesis

Academic Degrees

YearDegreeMajorInstitutionTownCountry
2016HDRUniversité Claude BernardLyon
2006PhDBiologyUniversidad ComplutenseMadridSpain
1997MDMedicineUniversidad de CaldasManizalesColombia


Current Research Projects

  • The epigenomic landscape of inflammation-related cancer

  • Early epigenetic changes (“drivers”) in cancer development and in adult stem cells

  • Epigenetic signatures of carcinogenic viruses


Selected Publications

Lambert MP, Ancey PB, Esposti DD, Cros MP, Sklias A, Scoazec JY, Durantel D, Hernandez-Vargas H, Herceg Z. Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors. Clin Epigenetics. 2015 Feb 27;7(1):15. PubMed PMID: 25755686.

Ancey PB, Testoni B, Gruffaz M, Cros MP, Durand G, Le Calvez-Kelm F, Durantel D, Herceg Z, Hernandez-Vargas H. Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes. Oncotarget. 2015 Dec 29;6(42):44877-91. PMID: 26565721.

Ichim G, Mola M, Finkbeiner MG, Cros MP, Herceg Z, Hernandez-Vargas H. The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle. Oncogene. 2014 Jan 9;33(2):181-92. PMID: 23318449.

Martin M, Ancey PB, Cros MP, Durand G, Le Calvez-Kelm F, Hernandez-Vargas H, Herceg Z. Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-β) is associated with a DNA methylome switch. BMC Genomics. 2014 Jun 5;15:435. PMID: 24898317.

Ouzounova M, Vuong T, Ancey PB, Ferrand M, Durand G, Le-Calvez Kelm F, Croce C, Matar C, Herceg Z, Hernandez-Vargas H. MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells. BMC Genomics. 2013 Feb 28;14:139. PMID: 23445407.