Who's Who

Hector Hernandez Vargas

Scientist

Epigenetics Group


Academic Degrees

YearDegreeMajorInstitutionTownCountry
2006PhDBiologyUniversidad ComplutenseMadridSpain
1997MDMedicineUniversidad de CaldasManizalesColombia


Current Research Projects

  • Establishment of enhancer epigenetic memory by Transforming Growth Factor Beta

  • Epigenetic signatures of carcinogenic viruses

  • A DNA methylation signature of childhood leukemia

  • The epigenomic landscape of inflammation-related cancer


Selected Publications

Lambert MP, Ancey PB, Esposti DD, Cros MP, Sklias A, Scoazec JY, Durantel D, Hernandez-Vargas H, Herceg Z. Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors. Clin Epigenetics. 2015 Feb 27;7(1):15. PubMed PMID: 25755686.

Hernandez-Vargas H, Castelino J, Silver MJ, Dominguez-Salas P, Cros MP, Durand G, Calvez-Kelm FL, Prentice AM, Wild CP, Moore SE, Hennig BJ, Herceg Z, Gong YY, Routledge MN. Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia. Int J Epidemiol. 2015 Apr 7. pii: dyv027. PMID: 25855716.

Ichim G, Mola M, Finkbeiner MG, Cros MP, Herceg Z, Hernandez-Vargas H. The histone acetyltransferase component TRRAP is targeted for destruction during the cell cycle. Oncogene. 2014 Jan 9;33(2):181-92. PMID: 23318449.

Ghantous A, Saffery R, Cros MP, Ponsonby AL, Hirschfeld S, Kasten C, Dwyer T, Herceg Z, Hernandez-Vargas H. Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling. BMC Biotechnol. 2014 Jul 1;14:60. PMID: 24980254.

Martin M, Ancey PB, Cros MP, Durand G, Le Calvez-Kelm F, Hernandez-Vargas H, Herceg Z. Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-β) is associated with a DNA methylome switch. BMC Genomics. 2014 Jun 5;15:435. PMID: 24898317.