Who's Who

Academic Degrees

2010PhDGeneticsUniversity of HelsinkiHelsinkiFinland
2003MScApplied microbiologyHelsinki University of TechnologyHelsinkiFinland

Current Research Projects

  • Early detection biomarkers in plasma for hepatocellular carcinoma.

  • Gene expression in human hepatocytes and HCC cell lines in the context of HBV infection and aflatoxin exposure.

  • TP53 mutations in head and neck cancer.

Selected Publications

Holmila R, Bornholdt J, Heikkilä P, Suitiala T, Fevotte J, Cyr D, Hansen J, Snellman S-M, Dictor M, Steiniche T, Sclünssen V, Schneider T, Pukkala E, Savolainen K, Wolff H, Wallin H, Luce D, Husgafvel- Pursiainen. (2010) Profile of TP53 gene mutations in sinonasal cancer. Int J Cancer; 127(3): 578-588

Holmila R, Bornholdt J, Suitiala T, Cyr D, Dictor M, Steiniche T, Wolff H, Wallin H, Luce D, Husgafvel-Pursiainen K. (2010) Profile of TP53 gene mutations in sinonasal cancer. Mutat Res – Fundam Molec Mech Mutagenesis; 686(1-2): 9-14

Anna L*, Holmila R*, Kovács K, Gyorffy E, Gyori Z, Segesdi J, Minárovits J, Soltész I, Kostic S, Csekeo A, Husgafvel-Pursiainen K, Schoket B. *Equal contribution. (2009) Relationship between TP53 tumor suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary. Mutagenesis; 24(6): 475-480

Holmila R, Cyr D, Luce D, Heikkilä P, Dictor M, Steiniche T, Stjernvall T, Bornholdt J, Wallin H, Wolff H, Husgafvel-Pursiainen K. (2008) COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure. Int J Cancer; 122(9): 2154-2159.

Holmila R and Husgafvel-Pursiainen K. (2006) Analysis of TP53 gene mutations in human lung cancer: Comparison of capillary electrophoresis single strand conformation polymorphism assay with denaturing gradient gel electrophoresis and direct sequencing. Cancer Detect Prev; 30(1): 1-6.