Who's Who

Cecilia Frecha

Postdoctoral Fellow

Infections and Cancer Biology Group


Specialty:

Virology, hematology and lentiviral vectors

Academic Degrees

YearDegreeMajorInstitutionTownCountry
2007European PhDLentiviral vectors for Gene TherapyUniversity of GranadaGranadaSpain
2003Research FellowImmunologyUniversity of Buenos AiresBuenos AiresArgentina
2002University DegreeBiochemistryUniversity of Buenos AiresBuenos AiresArgentina


Current Research Projects

  • Characterisation of beta genus cutaneous HPV impact on Innate Immunity
    Cecilia Frecha and Massimo Tommasino (Coordinator)


Selected Publications

Schoenhals M, Frecha C, Bruyer A, Caraux A, Veyrune JL, Jourdan M, Moreaux J, Cosset FL, Verhoeyen E, Klein B. (2012) Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins. Leukemia, July 26 (9) : 1663-70

Frecha C, Costa C, Nègre D, Amirache F, Trono D, Rio P, Bueren J, Cosset FL, and Verhoeyen E (2012) A novel lentivector targets gene transfer into hHSC in marrow from patients with BM-failure-syndrome and in vivo in humanized mice Blood, Feb 2;119 (5) : 1139-50

Frecha C, Lévy C, Costa C, Nègre D, Amirache F, Buckland R, Russell SJ, Cosset FL, Verhoeyen E. (2011) Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors. Journal of Virology, Jun;85 (12) : 5975-85

Frecha C, Costa C, Lévy C, Nègre D, Russell SJ, Maisner A, Salles G, Peng KW, Cosset FL, Verhoeyen E. (2009) Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukaemia cells using measles virus gp displaying lentiviral vectors. Blood, Oct 8;114 (15) : 3173-80

Frecha C., Costa C., Nègre D., Gauthier M., Peng K., Russell S., Cosset FL. and Verhoeyen E. (2008) Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins. Blood, Dec 15; 112 (13) : 4843-52

Scientific Societies Membership

Member of the European Society of Gene and Cell Therapy
Member of the Spanish of Gene and Cell Therapy

Prizes, Honours

Young Investigator Award: Awarded by the Consortium: Adoptive Engineering T cell targeting to activate cancer killing (ATTACK) in the "Cellular Therapy of Cancer Symposium", September 24th-27th, 2010., Montpellier
Best Oral Presentation Award: Awarded by the Société Francophone de Thérapie Cellulaire et Génique, in the VIII Meeting of the SFTGC 21-23 Juin 2009, Paris.