Who's Who

Davide Degli Esposti


Epigenetics Group


Mechanisms of carcinogenesis, Long-term carcinogenicity bioassays, molecular pathophysiology

Academic Degrees

2011PhDCellular and Molecular PathophysiologyUniversité Paris-Sud 11OrsayFrance
2000MScIndustrial BiotechnologyUniversity of BolognaBolognaItaly

Current Research Projects

  • Non-coding RNAs profiling in liver cancer

  • Epigenomic analysis of head and neck cancers

  • Functional miRNA analysis in breast cancer development

  • Epigenetic mechanistic data in carcinogen evaluation

Selected Publications

Degli Esposti D, Hernandez-Vargas H, Voegele C, Fernandez-Jimenez N, Forey N, Bancel B, Le Calvez-Kelm F, Mckay J, Merle P, Herceg Z. (2016) Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing. Oncotarget. doi:10.18632/oncotarget.7364

Degli Esposti D, Hamelin J, Bosselut N, Saffroy R, Sébagh M, Pommier A, Martel C, Lemoine A. (2012) Mitochondrial roles and cytoprotection in chronic liver injury. Biochemistry Research International : 2012:387626

Degli Esposti D, M Sebagh, P Pham, M Reffas, C Poüs, C Brenner, D Azoulay, A Lemoine. (2011) Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes. Cell Death and Disease : 2:e111

Degli Esposti D, Domart MC, Sebagh M, Harper F, Pierron G, Brenner C, Lemoine A. (2010) Autophagy is induced by ischemic preconditioning in human livers formerly treated by chemotherapy to limit necrosis. Autophagy, Vol 1 : 172-174

Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A (2006) First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environmental Health Perspectives 114(3) : 379-385

Prizes, Honours

September 2009. Award of International Society of Doctors for the Environment (ISDE Italy) in memory of Lorenzo Tomatis.
June 2008. Research Fellowship by Association NRB Vaincre le cancer
June 2008. Research Fellowship by Groupement cooperatif de transplantation d Ile de France