Who's Who

Xavier Castells

Postdoctoral Fellow

Molecular Mechanisms and Biomarkers Group


Specialty:

Postdoctoral Fellowship

Academic Degrees

YearDegreeMajorInstitutionTownCountry
2009PhDBiochemistry and Molecular BiologyUniversitat Autònoma de BarcelonaCerdanyola del VallèsCatalonia, Spain
2005MScBiochemistry and Molecular BiologyUniversitat Autònoma de BarcelonaCerdanyola del VallèsCatalonia, Spain
2003BScBiochemistry and Molecular BiologyUniversitat Autònoma de BarcelonaCerdanyola del VallèsCatalonia, Spain


Current Research Projects

  • MicroRNAs as biomarkers of early carcinogenesis in urothelial tissues
    Collaborators: J Nortier, B Jelakovic; AP Grollman

  • Toxicogenomic aspects of aristolochic acid-associated nephropathy and urinary tract carcinogenesis
    Collaborators: AP Grollman, T Rosenquist, K Dickman (model systems), J Nortier, B Jelakovic (clinical samples)


Selected Publications

Jelakovic B, Castells X, Tomic K, Ardin M, Karanovic S, and Zavadil J. (2014) Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid. Int J Cancer. Accepted manuscript online: 2014 Nov 17. doi: 10.1002/ijc.29338. [Epub ahead of print] PubMed PMID: 25403517

Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallee MP, McKay J, Nedelko T, Muehlbauer KR, Marusawa H, Alexander J, Hazelwood L, Byrnes G, Hollstein M, Zavadil J. (2014) Modelling mutational landscapes of human cancers in vitro. Sci Rep 4 4482

Castells X, Acebes JJ, Majós C, Boluda S, Julià-Sapé M, Candiota AP, Ariño J, Barceló A, Arús C. (2012) Development of robust discriminant equations for assessing subtypes of glioblastoma biopsies. Br J Cancer 106 (11): 1816-25

Tortosa R, Castells X, Vidal E, Costa C, Ruiz de Villa M del C, Sánchez A, Barceló A, Torres JM, Pumarola M, Ariño J. (2011) Central nervous system gene expression changes in a transgenic mouse model for bovine spongiform encephalopathy. Vet Res 42(1): 109

Castells X, Acebes JJ, Boluda S, Moreno-Torres A, Pujol J, Julià-Sapé M, Candiota AP, Ariño J, Barceló A, Arús C. (2010) Development of a predictor for human brain tumours based on gene expression values obtained from two types of microarray technologies. OMICS : A Journal of Integrative Biology 14(2): 157-64

Scientific Societies Membership

AACR - American Society for Cancer Research
Societat Catalana de Biologia
Sociedad Española de Bioquímica y Biología Molecular