Centre des Médias - Nouvelles du CIRC

2014

IARC Meetings - Emerging Issues in Head and Neck Cancer and Emerging Oncogenic Viruses: DEADLINE EXTENDED FOR EARLY REGISTRATIONS
09/04/2014 -
Early Registrations have been extended for the following two IARC Meetings:
Emerging Issues in Head and Neck Cancer
2-3 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy
Registration Deadline Extended until 17 April

Emerging Oncogenic Viruses
4-8 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy
Registration Deadline Extended until 7 April.


To register: Emerging Issues in Head and Neck Cancer , Emerging Oncogenic Viruses
IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism / Biomarkers Group
07/04/2014 -
A postdoctoral opportunity is immediately available within the Group to apply metabolomic methodologies based on high performance liquid chromatography and high-resolution mass spectrometry to the discovery of new biomarkers of exposure related to cancer risk. The postdoctoral fellow will work in an innovative, well-equipped and scientifically stimulating environment. The research proposed is part of national and international projects involving leading research groups in the fields of cancer epidemiology and funded by the European Project EurocanPlatform (http://www.eurocanplatform.eu/).
Deadline: 15 May 2014
Pour plus d'informations
IARC Working Group Report No 7: Primary End-points for Prophylactic HPV Vaccine Trials
01/04/2014 -
The potential of the current licensed preventive virus-like particle human papillomavirus (HPV) vaccines to have a major public health impact is leading to additional clinical trials.

The International Agency for Research on Cancer (IARC)/United States National Cancer Institute (NCI) Expert Meeting of September 2013 brought together a Working Group composed of experts from the non-profit public and academic sectors who possessed a wide range of expertise relevant to HPV vaccines. The Working Group reviewed the scientific evidence as to whether it might be appropriate to use a virological end-point, rather than a disease end-point such as cervical intraepithelial neoplasia of grade 2 or worse (CIN2+), as the primary end-point for some future clinical efficacy trials, and the circumstances under which immunobridging trials might be sufficient for licensure. Virological end-points could accelerate vaccine evaluation and licensure.

The Working Group developed recommendations for clinical trial primary end-points that could also include post-trial follow-up recommendations.

Read the Report
The African Breast Cancer - Disparities in Outcomes study
28/03/2014 -
The African Breast Cancer - Disparities in Outcomes (ABC-DO) study is a multi-country sub-Saharan African study of determinants of breast cancer outcomes. The number of women diagnosed with breast cancer per year is rising rapidly in Africa, and the consequences of poor survival are worsened by the young age of women affected. ABC-DO will recruit women from four public hospitals in Nigeria, Uganda, South Africa, and Namibia and examine the full journey of breast cancer patients, both pre- and post-diagnosis, in order to identify modifiable determinants of survival, to be able to prevent avoidable deaths from breast cancer in African women.

Visitez le site web
Modelling mutational landscapes of human cancers
27/03/2014 -
A new report by investigators from the International Agency for Research on Cancer (IARC) describes how key aspects of cancer development can be modelled in cultured cells treated with carcinogenic chemicals. This first-of-its-kind study uses innovative genomics and bioinformatics approaches to establish specific mutation fingerprints left in the cellular DNA by carcinogens during cellular immortalization and clonal expansion, two characteristics of cancer development. The study was published today in the Nature Publishing Group’s Scientific Reports.

Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallée MP, McKay J, Nedelko T, Muehlbauer KR, Marusawa H, Alexander J, Hazelwood L, Byrnes G, Hollstein M, Zavadil J.
Modelling mutational landscapes of human cancers in vitro. Scientific Reports (NPG). 4:4482; published on 27 March 2014; DOI:10.1038/srep04482.
Read article
Interview with Dr Christopher Wild for the Spanish newspaper La Vanguardia|La Contra: Yo puedo decirle cómo evitar la mitad de los cánceres
17/03/2014 -
Interview with Dr Christopher Wild for the Spanish newspaper La Vanguardia|La Contra: Yo puedo decirle cómo evitar la mitad de los cánceres
Read more
Relaunch of the IARC Handbooks of Cancer Prevention
11/03/2014 -
The IARC Monographs Programme is proud to announce the relaunch of the IARC Handbooks of Cancer Prevention. The IARC Handbooks programme was launched in 1995 to complement the IARC Monographs by providing evaluations of approaches to cancer prevention. The first 14 volumes evaluated the cancer-preventive activity of chemopreventive agents and of preventive actions, the effectiveness of screening, and the effectiveness of tobacco control.

Volume 15 will evaluate Breast Cancer Screening. Breast cancer is the most common cancer in women worldwide, in both developed and developing countries, and the potential role of primary prevention is limited because most risk factors for breast cancer are directly linked with endogenous hormone levels and reproductive choices. Therefore, secondary prevention encompassing all forms of screening for breast cancer is a priority. In 2002, an IARC Working Group developed IARC Handbook Volume 7 on Breast Cancer Screening. Today, an up-to-date, objective, and independent evaluation of the benefits and harms of all modalities of screening in different age groups and different settings is urgently needed.

IARC Handbooks of Cancer Prevention Vol. 15: Breast Cancer Screening (11-18 November 2014)
Call for Data (closing date 15 October 2014)
Call for Experts (closing date 31 March 2014)
Request for Observer Status (closing date 11 July 2014)
WHO Declaration of Interests for this volume

Pour plus d'informations , Regarder la brochure
IARC welcomes visitors from Inje University, Republic of Korea
25/02/2014 -
The International Agency for Research on Cancer (IARC) is pleased to welcome 21 students and faculty from the Global Health Research Center of Inje University, Republic of Korea.

The students will meet with Dr Christopher Wild, Director of IARC, and Dr Eduardo Seleiro, who will provide an overview of the Agency′s research activities and present the latest cancer trends.

Cancer is a leading cause of death in the Republic of Korea, which has been an IARC Participating State since 2006. Seven postdoctoral researchers from the country have been trained at the Agency so far.

The Agency also has a number of partnerships with the Republic of Korea and is currently setting up a large study on gastric cancer prevention integrated into the national gastric cancer screening programme.

In early March, Dr Wild will visit the Republic of Korea to attend the 5th meeting of the Asian National Cancer Centres Alliance (ANCCA).

More information about the meeting
IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism /Nutritional Epidemiology Group
19/02/2014 -
Call for applications for a postdoctoral opportunity within the Section of Nutrition and Metabolism / Nutritional Epidemiology Group.

A postdoctoral opportunity (biostatistician/epidemiologist) is available from April 2014 within the Group to work on the identification of dietary and lifestyle determinants in the occurrence of multi-morbidity, here defined as the occurrence of more than one non-communicable disease (cancer, cardio-vascular disease or diabetes).
Deadline: 31 March 2014
Read more
World Cancer Report 2014 - Prevention is Crucial
14/02/2014 -
On 3 February 2014, the International Agency for Research on Cancer (IARC) released World Cancer Report 2014, a collaboration of over 250 leading scientists from more than 40 countries, describing multiple aspects of cancer research and control.
In a new video, the IARC Director, Dr Christopher P. Wild, presents key messages of the Report, emphasizing the need for prevention to address the alarming rise in cancer burden globally. About half of all cancers could be avoided if current knowledge was adequately implemented.
Regarder la video , Lire Communiqué de Presse No 224
Stages post-doctoraux - Section/Groupe: Nutrition et métabolisme - Groupe Epidémiologie nutritionnelle - Nouvelle date de clôture: 31 Mars 2014
12/02/2014 -
A postdoctoral opportunity is available immediately within the Nutritional Epidemiology Group for a biostatistician to work on an integrated approach to combine self-reported and biomarker estimates of dietary exposure, with the aim of exploring the misclassification inherent in these measurements.
Nouvelle date de clôture: 31 Mars 2014
Plus d’informations en anglais
Senior Visiting Scientist Award 2013
10/02/2014 -
The recipients of the 2013 highly competitive Senior Visiting Scientist Award, currently at IARC, are:

Professor Leticia M. Fernandez Garrote from the National School of Public Health, Havana, Cuba,

Professor John D. Groopman from the Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA,

Professor Groesbeck P. Parham from the Center for Infectious Disease Research in Zambia (CIDRZ) Cervical Cancer Prevention Programme, Lusaka, Zambia (an affiliate of University of North Carolina, Chapel Hill, NC, USA), and

Professor Christopher J. Portier Senior Collaborating Scientist, Environmental Defense Fund, New York, USA.

Read more
World Cancer Day 2014
04/02/2014 -
As every year on 4 February, World Cancer Day, the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC) support the Union for International Cancer Control (UICC) in promoting ways to reduce the global burden of cancer. The theme of World Cancer Day 2014 is “Debunk the Myths”.

On 4 February, IARC will host the 2nd IARC Cancer and Society Lecture, featuring Prof. Sir Michael G. Marmot. The title of Professor Marmot’s talk is “Fair society, healthy lives” (See Programme).

See links to WHO , UICC
La bataille mondiale contre le cancer ne pourra se gagner avec les seuls traitements. Il faut mettre en œuvre d'urgence des mesures de prévention efficaces pour éviter une crise du cancer
03/02/2014 -
Le Centre international de Recherche sur le Cancer (CIRC), l'agence spécialisée sur le cancer de l'Organisation mondiale de la Santé, lance aujourd'hui le Rapport sur le cancer dans le monde 2014 (World Cancer Report 2014), fruit de la collaboration de plus de 250 éminents chercheurs de plus de 40 pays différents, et détailllant de multiples aspects de la recherche et de la lutte contre le cancer.
Acheter World Cancer Report 2014
Lire Communiqué de Presse No 224 , Regarder B-roll
The Lancet - Alcohol and mortality in Russia: prospective observational study of 151 000 adults
31/01/2014 -
A paper published in The Lancet and led by scientists from the International Agency for Research on Cancer (IARC), along with colleagues from the Russian Cancer Research Centre in Moscow and Oxford University in the United Kingdom, provides strong evidence that the high and sharply fluctuating death rates in Russia are due mainly to alcohol, and particularly vodka.

The study asked 151 000 people how much vodka they drank, and then followed them for up to a decade, during which 8000 died. The researchers estimate that the 20-year risks of death at ages 35–54 years were 35% for men who had reported drinking three or more half-litre bottles of vodka a week, compared with 16% for men who had reported consuming less than half a litre a week. The corresponding risks of death at ages 55–74 years were 64% and 50%, respectively.

Dr Christopher Wild, Director of IARC, commented that these results reinforce the importance of alcohol as a cause of premature mortality in Russia. They also highlight the potential to reduce premature mortality by 25% by 2025 using measures that curb harmful alcohol consumption. Study leader Professor David Zaridze from the Russian Cancer Research Centre in Moscow added, “The significant decline in Russian mortality rates following the introduction of moderate alcohol controls in 2006 demonstrates the reversibility of the health crisis from hazardous drinking. People who drink spirits in hazardous ways greatly reduce their risk of premature death as soon as they stop.”

D Zaridze, S Lewington, A Boroda, G Scélo et al.
Alcohol and mortality in Russia: prospective observational study of 151 000 adults.
The Lancet, Early Online Publication, 31 January 2014, http://dx.doi.org/10.1016/S0140-6736(13)62247-3

Read article , Lancet Press Release
IARC Publications – IARC Biennial Report 2012–2013
28/01/2014 -
This Biennial Report of the International Agency for Research on Cancer (IARC) provides a summary of the activities of the Agency during the 2012–2013 biennium. These activities span research areas including descriptive epidemiology, cancer registration and analysis of data on cancer occurrence and trends, basic research into the genetic and molecular aspects of cancer development, pathogenesis, and prevention studies. This report demonstrates the high scientific quality of the work emanating from the Agency and the direct relevance of the findings to cancer control and prevention.
Download
Education and Training Programme website launched
28/01/2014 -
IARC is pleased to announce the launch of a new dedicated Education and Training Programme website, also available on mobile platforms. This serves as an online single entry point to all IARC education and training initiatives, including fellowships and courses, opportunities for Early Career Scientists, and a database that links to existing online IARC learning and training resources such as digital training manuals.
Visit website
The Lancet Oncology - International variations in childhood cancer in indigenous populations: a systematic review
27/01/2014 -
A paper, led by scientists of the Menzies School of Health Research (Australia) and the International Agency for Research on Cancer (IARC) and published in Lancet Oncology, reports for the first time the burden of cancer in indigenous children worldwide. Forty-four studies among indigenous children from three main regions were included: Native Americans (American Indians, Alaska Natives, and Hawaiians) in the USA, indigenous children from the Asia–Pacific region (Indigenous Australians, Maori, and Pacific Islanders in New Zealand and French Polynesia), and indigenous children from selected African countries. Little information was available on cancer profiles of indigenous children in some regions with large indigenous populations, such as South America and the circumpolar region (e.g. in the Saami and Nenets populations).

Compared with non-indigenous children, indigenous children had similar or lower incidences of all cancers combined, but patterns of incidence varied by country. The distribution of cancer types in indigenous children more closely reflected that of non-indigenous children within their own country, rather than of other indigenous groups. Cancer mortality rates were available only for Australia, the USA, and New Zealand, and were similar in indigenous and non-indigenous children in the USA and Australia. Cancer survival was overall lower for indigenous children.
These findings highlight the paucity of accessible information and the pressing need for cancer data by indigenous status in population-based cancer registries. The authors advocate the better measurement of cancer burden among indigenous children so that targeted programmes for cancer control can be planned and implemented.

Valery PC, Moore S, Meiklejohn J, Bray F.
International variations in childhood cancer in indigenous populations: a systematic review.
The Lancet Oncology, Volume 15, Issue 2, Pages e90 - e103, February 2014, doi:10.1016/S1470-2045(13)70553-9
Read article
IARC Meetings - Emerging Issues in Head and Neck Cancer and Emerging Oncogenic Viruses: REGISTRATION NOW OPEN!
15/01/2014 -
Registration is now open for the following two IARC Meetings:

Emerging Issues in Head and Neck Cancer
2-3 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy

Emerging Oncogenic Viruses
4-8 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy

For both meetings, the registration deadline is 9 May 2014.
To register: "Emerging Issues in Head and Neck Cancer" , “Emerging Oncogenic Viruses”
IARC Publications - PDFs online - Effectiveness of Tax and Price Policies for Tobacco Control - IARC Handbook of Cancer Prevention Volume 14
14/01/2014 -
IARC Handbook of Cancer Prevention Volume 14

"Effectiveness of Tax and Price Policies for Tobacco Control" is now available in PDF format.

Download here
Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data.
09/01/2014 -
A paper led by scientists of the International Agency for Research on Cancer (IARC) published in the European Journal of Cancer predicts there will be 23,000 new cases of testicular cancer annually in Europe by 2025, a rise of 24% from 2005. The predictions are based on an extrapolation of recent trends in recorded incidence from high-quality population-based cancer registries in Europe using age-period-cohort models.

While testicular cancer incidence rates are increasing in most countries, signs of a transition are apparent, with stabilising rates in certain high-risk countries in Northern and Western Europe (Denmark, Germany, Austria, Switzerland and England) offset by rapid increases in incidence rates in a number of Southern European countries, including Croatia, Slovenia, Italy and Spain. The authors predict that around one in 100 men may be diagnosed with the disease annually in the highest risk countries of Europe (Croatia, Slovenia and Norway) circa 2025. The article aims to support the planning of services and prioritisation of the necessary resources in European countries, ensuring equitable management and provision of care for testicular cancer patients in the future.

Le Cornet C, Lortet-Tieulent J, Forman D, Béranger R, Flechon A, Fervers B, Schüz J, Bray F.
Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data.
Eur J Cancer. 2013 Dec 23. pii: S0959-8049(13)01054-X. doi: 10.1016/j.ejca.2013.11.035. [Epub ahead of print]

Read article at EJC website , Science Direct
21st Roger Sohier Lecture - 10 January 2014
08/01/2014 -
Dr Harold Varmus, co-recipient of a Nobel Prize for studies of the genetic basis of cancer and US National Cancer Institute (NCI) Director will present the 21st Roger Sohier Lecture on 10 January at the International Agency for Research on Cancer (IARC). The title of Dr Varmus's talk is "Promoting the discovery and application of knowledge about cancer".

He will then receive the IARC Medal of Honour from the Director of the Agency, Dr Christopher P. Wild, for his career-long contribution to cancer research.

Visit NCI Director's Page
REMINDER IARC Monographs Meeting: Comité Consultatif pour la Recommandation des Priorités des Monographies du CIRC pour les années 2015-2019
07/01/2014 -
The deadline for submitting the form to nominate agents for consideration in future IARC Monographs is Friday, January 31 2014.

Advisory Group to Recommend Priorities for IARC Monographs during 2015-2019 (7-9 April 2014)
Information on how to submit a nomination, and about the Advisory Group
Form for Nomination of Agents (closing date 31 January 2014)
Declaration of interests for individuals submitting nominations

See IARC Monographs website
In The cancer wars Lancet series, IARC Director emphasizes primary prevention as the most effective way to fight cancer
06/01/2014 -
In a piece entitled “Global cancer patterns: causes and prevention”, IARC Director Dr Christopher Wild, and long-time IARC collaborator Dr Paolo Vineis show that in view of the growing global cancer burden, primary prevention is a particularly effective –and probably also cost-effective– approach to curbing the increase: whilst between a third and half of all cancers are preventable on the basis of current knowledge, “structural interventions (including bans, taxation, and urban planning)” are needed, however, which can benefit other people, reduce shared risk factors associated with other noncommunicable diseases, and can completely remove or reduce some long-term causes of cancer.

Global cancer patterns: causes and prevention
Paolo Vineis, Christopher P Wild
The Lancet, Early Online Publication, 16 December 2013
doi:10.1016/S0140-6736(13)62224-2

Read Article , Read Editorial
Publications du CIRC - Monographies en PDF
05/01/2014 -
Volume 106: Trichloroéthylène, tetrachloroéthylène et d'autres agents chlorés
Nous avons le plaisir d'annoncer que six Monographies du Volume 106 sont désormais disponible. La Monographie restante, Trichloroéthylène, et le volume complet seront postés sous peu.

Volume 105: Gaz d’échappement des moteurs diesel et des moteurs à essence, et certains nitro-arènes
Nous avons le plaisir d'annoncer que ce volume est désormais disponible en ligne.

Télécharger Volume 106 , Volume 105
IARC Monographs - Upcoming Meetings - Volume 111: Some Nanomaterials and Some Fibres
05/01/2014 -
Meeting Volume 111: "Some Nanomaterials and Some Fibres" is announced
30 September - 7 October 2014

Call for Data (closing date 3 September 2014)
Call for Experts (closing date 30 January 2014)
Request for Observer Status (closing date 3 June 2014)
WHO Declaration of Interests for this volume

See IARC Monographs website