IARC News
Coffee drinking and mortality in 10 European countries: a multinational cohort study
11/07/2017
A new study coordinated by the International Agency for Research on Cancer (IARC) and published today in Annals of Internal Medicine examines whether coffee consumption is associated with all-cause and cause-specific mortality. Based on the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, the research included more than 521 300 participants from 10 European countries and is the largest analysis of coffee consumption and mortality currently available. The results suggest that higher levels of coffee drinking are associated with lower risk of death from various causes, and in particular digestive and circulatory diseases.
Gunter MJ, Murphy N, Cross AJ, Dossus L, Dartois L, Fagherazzi G, et al.
Coffee drinking and mortality in 10 European countries: a multinational cohort study
Ann Intern Med, [Epub ahead of print 11 July 2017] doi: 10.7326/M16-2945
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Experimental modelling of cancer driver events
11/07/2017
New research led by the International Agency for Research on Cancer (IARC) studies drivers of cell immortalization, a hallmark of cancer, using an experimental carcinogen exposure system and state-of-the-art genomics technologies. The report, published today in the journal Oncogene, identifies novel putative cancer driver genes not yet recognized by large-scale cancer genome sequencing projects. The research highlights the potential for the systems wider application in complementing tumour sequencing in the discovery and functional characterization of early biomarkers of carcinogenic transformation.
Huskova H, Ardin M, Weninger A, Vargova K, Barrin S, Villar S, et al.
Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing
Oncogene, Published online 10 July 2017;
http://dx.doi.org/10.1038/onc.2017.215
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Mammographic density and ageing: a collaborative pooled analysis of cross-sectional data from 22 countries worldwide
04/07/2017
A new study coordinated by the International Agency for Research on Cancer (IARC) and published in PLoS Medicine assesses the variations in breast density with ageing in 22 countries worldwide, in order to evaluate the basic epidemiology of this strong marker of breast cancer risk. The results indicate that declines in breast density with ageing and through the menopausal transition appear to be an inherent feature of this risk marker in women worldwide.
Burton A, Maskarinec G, Perez-Gomez B, Vachon C, Miao H, Lajous M, et al.
Mammographic density and ageing: a collaborative pooled analysis of cross-sectional data from 22 countries worldwide
PLoS Med, Published online 30 June 2017;
https://doi.org/10.1371/journal.pmed.1002335
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Press Releases
Publications
WHO Classification of Tumours of Endocrine Organs
28/06/2017
The WHO Classification of Tumours of Endocrine Organs is the tenth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome.
The book, prepared by 166 authors from 25 countries, contains more than 700 colour images and tables, and more than 3100 references.
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