Actualité du CIRC

Dons de particuliers pour la recherche du CIRC

25/07/2017 Le Centre international de Recherche sur le Cancer (CIRC) est très reconnaissant de l’aide financière qu’il reçoit des contributions volontaires, qui sert à élaborer et renforcer ses activités de recherche. Ces fonds jouent un rôle essentiel dans le soutien des programmes de recherche et de formation du Centre, ainsi que dans la prévention du cancer dans le monde entier.

Afin de permettre à tous de contribuer à la lutte contre le cancer, le Centre a réorganisé sa page Dons qui fournira aux visiteurs les informations nécessaires au soutien à la recherche du CIRC.

Ensemble, nous pourrons enfin mieux comprendre les causes du cancer et veiller à ce qu’il puisse être évité, détecté et traité aussi tôt et efficacement que possible.

Prévenons le cancer –ensemble..
Visitez la page web Dons

Genome-scale mutational signatures of aflatoxin in cells, mice and human tumours

24/07/2017 A new study published today in Genome Research models a first-of-its-kind approach to exploring the causes of cancer by combining cell and animal experimental studies with genome-wide sequencing of human tumours. Specific patterns of DNA mutations identified in human tumours were reproduced via in vivo and in vitro experimental studies, providing key insights into the mutagenic agents that underlie the development of cancer.

Huang MN, Yu W, Teoh WW, Ardin M, Jusakul A, Ng A, et al.
Genome-scale mutational signatures of aflatoxin in cells, mice and human tumours. Genome Res. Published online 24 July 2017. http://www.genome.org/cgi/doi/10.1101/gr.220038.116
Read article , Read IARC Press Release 252

Asbestos-associated genome-wide DNA methylation changes in lung cancer

23/07/2017 A study by the International Agency for Research on Cancer (IARC) provides new evidence that asbestos exposure may induce DNA methylation changes in specific genes. IARC researchers, in partnership with the Finnish Institute of Occupational Health in Helsinki, carried out a genome-wide DNA methylation analysis of lung cancer tissue samples for which detailed asbestos exposure and clinical data were available, and compared the samples with normal lung tissue. The research, published last week in the International Journal of Cancer (IJC), provides key insights into the mechanisms associated with asbestos exposure that contribute to lung cancer. It also identifies new potential biomarkers of asbestos exposure.

Kettunen E, Hernandez-Vargas H, Cros MP, Durand G, Le Calvez-Kelm F, Stuopelyte K, et al.
Asbestos-associated genome-wide DNA methylation changes in lung cancer
Int J Cancer. 2017 Jul 19. doi: 10.1002/ijc.30897. [EPUB ahead of print]
Read article

Publications

WHO Classification of Tumours of Endocrine Organs

28/06/2017 The WHO Classification of Tumours of Endocrine Organs is the tenth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome.

The book, prepared by 166 authors from 25 countries, contains more than 700 colour images and tables, and more than 3100 references.
Read more