IARC News

Benchmarking life expectancy and cancer mortality: global comparison with cardiovascular disease 1981–2010

22/06/2017 A new study coordinated by the International Agency for Research on Cancer (IARC) and published today in the British Medical Journal (BMJ) assesses the global impact of cancer compared with cardiovascular disease (CVD) on changes in life expectancy. Using data from 52 populations included in the World Health Organization Mortality Database over the period 1981–2010, the study shows that declining cancer mortality rates were responsible for up to 20% of the overall gains in life expectancy at ages 40–84 years. Declining CVD mortality rates had the greatest impact and were responsible for more than 50% of the overall gains experienced.

Cao B, Bray F, Beltrán-Sánchez H, Ginsburg O, Soneji S, Soerjomataram I
Benchmarking life expectancy and cancer mortality: global comparison with cardiovascular disease 1981–2010
BMJ. Published online 22 June 2017; http://dx.doi.org/10.1136/bmj.j2765
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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

19/06/2017 A new large-scale association analysis coordinated by scientists from the International Agency for Research on Cancer (IARC) and published in Nature Genetics identifies new lung cancer susceptibility loci. The new loci highlight the striking heterogeneity in genetic susceptibility across the histological subtypes of lung cancer. In this analysis, 14 803 cases and 12 262 controls of European descent were genotyped on the OncoArray and combined with existing data for an aggregated genome-wide association study (GWAS) analysis of lung cancer in 29 266 cases and 56 450 controls.

McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, et al.
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
Nat Genet. Published online 12 June 2017;
http://dx.doi.org/10.1038/ng.3892
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IARC and the National Cancer Institute of Thailand sign new agreement

16/06/2017 The International Agency for Research on Cancer (IARC) is pleased to announce the signature of a new Letter of Agreement with the National Cancer Institute of Thailand, as part of IARC’s Global Initiative for Cancer Registry Development (GICR), to establish an IARC/GICR Collaborating Centre in Bangkok. The areas of focus of the new Collaborating Centre will include the delivery of tailored training courses in East Asia and the development of networks to promote population-based cancer registration and improve the quality and use of registry data in the region. View photos

Publications

Common Minimum Technical Standards and Protocols for Biobanks Dedicated to Cancer Research

15/05/2017 Biobanking has developed at a rapid pace in recent years, initiated by the drive for personalized medicine, the need for high-quality biological resources and associated data for scientific research, and technological advancement of analytical platforms for molecular and genetic research.
This book includes guidelines and recommendations for biobanks not only in high-income countries but also in low- and middle-income countries (LMICs). The recommendations are based on validated and/or evidence-based guidelines.
The book also includes sections on sample sharing, ethical, legal, and social issues (ELSI), and harmonization guidelines important to support collaborative research efforts that make use of biological materials.
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