A new study led by researchers from the International Agency for Research on Cancer (IARC) assessed the presence of TP53 mutations in the cell-free DNA extracted from the plasma of 51 small-cell lung cancer (SCLC) cases and 123 non-cancer controls. The results raise hopes that circulating tumour DNA could play a significant role in the early detection of SCLC, particularly in smokers.
Identification of circulating tumor DNA for the early detection of small-cell lung cancer
Fernandez-Cuesta L, Perdomo S, Avogbe PH, Leblay N, Delhomme TM, Gaborieau V, et al.
EBioMedicine. 2016; http://dx.doi.org/10.1016/j.ebiom.2016.06.032
The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization, has evaluated the carcinogenicity of drinking coffee, maté, and very hot beverages. The detailed assessments will be published as Volume 116 of the IARC Monographs. A summary of the evaluations has now been published in The Lancet Oncology. Also available are a Q&A on the Volume 116 evaluations, a Fact sheet and Debunking the myths.
Loomis D, Guyton KZ, Grosse Y, Lauby-Secretan B, El Ghissassi F, Bouvard V, et al. Carcinogenicity of drinking coffee, maté, and very hot beverages The Lancet Oncology, Published online 15 June 2016; http://dx.doi.org/10.1016/S1470-2045(16)30239-X Read article, Read IARC Press Release 244
WHO Classification of Tumours of the Central Nervous System
WHO/IARC Classification of Tumours, 4th Edition Revised, Volume 1
Edited by Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Ellison DW, Figarella-Branger D, Perry A, Reifenberger G, von Deimling A
WHO Classification of Tumours of the Central Nervous System is the Revised 4th Edition of the WHO series on histological and genetic typing of human tumours.
Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 122 authors from 19 countries, contains more than 800 colour images and tables, and more than 2800 references.