Media Centre - IARC NEWS
|Blood Cancer Journal - No association seen between exposure to extremely low frequency magnetic fields and risk of relapse or overall survival in children with acute lymphoblastic leukaemia|
In a collaborative study led by IARCÂ’s Section of Environment and Radiation and the Danish Cancer Society Research Center, published online in Blood Cancer Journal today, researchers investigated whether exposure to extremely low frequency (ELF) magnetic fields (50/60 Hz), as occurs for instance in the vicinity of high-voltage power lines, increases the risk of relapse in children with acute lymphoblastic leukaemia (ALL) or has an impact on their survival probability.
J SchĂĽz, K Grell, S Kinsey, MS Linet, MP Link, G Mezei, BH Pollock, E Roman, et al.
Extremely low-frequency magnetic fields and survival from childhood acute lymphoblastic leukemia: an international Q1 follow-up study.
Blood Cancer Journal (2012) 2, e98; doi:10.1038/bcj.2012.43; published online 21 December 2012
Link to PDF , Link to the article
|IARC Publications - IARC Monographs in PDF|
Volume 101: Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water.
The complete volume of 18 Monographs is now available online.
|UICC Â– IARC Development Fellowship. 2012 Award Winner|
The Union for International Cancer Control (UICC) and the International Agency for Research on Cancer (IARC) are pleased to announce the award of the UICC-IARC Development Fellowship of a value of USD 10,000 to:
Dr Oresto Michael Munishi, Director of the Kilimanjaro Cancer Registry, Kilimanjaro Christian Medical Centre, Moshi, United Republic of Tanzania
|Fondation Association pour la recherche sur le cancer (ARC) - Interview of Zdenko Herceg: Epigenetic regulation and cancer development|
Focus Grands Projets: Epigenetic regulation and cancer development
Dr Zdenko Herceg received 5 different grants from Fondation ARC on the last decade. His Group conducts both mechanistic studies and epigenetic profiling, aiming to gain a better mechanistic understanding of tumorigenesis, and to discover and validate new cancer biomarkers.
|New Release of the IARC TP53 Database|
The Molecular Mechanisms and Biomarkers Group is pleased to announce the release of a new version of the IARC TP53 Database.
The IARC TP53 Database compiles TP53 gene variations identified in human populations and tumour samples, with associated data on tumour pathology and patient characteristics. The following molecular epidemiology data sets are available:
-TP53 somatic mutations in sporadic cancers
-TP53 germline mutations in familial cancers
-Common TP53 polymorphisms identified in human populations
-Functional and structural properties of p53 mutant proteins
-TP53 gene status in human cell lines
-Mouse models with engineered TP53.
This new release, R16 (November 2012), features an updated database that can be searched and analysed with new interactive tools through a redesigned web interface.
|IARC Postdoctoral Opportunities - Section of Mechanisms of Carcinogenesis|
Call for applications for a postdoctoral opportunity within the Section of Mechanisms of Carcinogenesis
Deadline: 8 January 2013
|Nature - News - Daily dose of toxics to be tracked|
New technologies for sensing chemicals that people are exposed to and their effects in the body will help scientists work towards a complete picture of how environmental pollutants influence health. The exposome, a concept developed by Dr Christopher Wild, Director, IARC, is the sum of all of the environmental components, including lifestyle factors and chemicals we are exposed to, that influence our health over the course of a lifetime.
Nature News describes the Exposomics project, an ambitious project whose lead scientists believe will benefit public health in ways that genome research so far has not.
|IARC Summer School in Cancer Epidemiology 2013|
Summer School in Cancer Epidemiology
17 June - 5 July 2013
Two modules will be held: Cancer Registration: Principles and Methods and Introduction to Cancer Epidemiology.
The deadline for applications is 14 January 2013
See Course Schedule, Support Letter Template and Online Application Form
|IARC Fellowships - Expertise Transfer Fellowship Deadline Extended|
The application period for the "Expertise Transfer Fellowship" has been extended to 31 December 2012.
|IARC participation in a conference in Kiev, Ukraine, entitled: "Chrysotile Asbestos: Risk Assessment & Management"|
The Agency is about to participate in a conference in Kiev, Ukraine, entitled: "Chrysotile Asbestos: Risk Assessment & Management". Our agreement to participate has caused some concerns to which the Agency is sensitive.
|New Partnership with the International Association of National Public Health Institutes (IANPHI)|
The Agency has established a new key partnership with the International Association of National Public Health Institutes (IANPHI).
IANPHI is a global network of national public health institutes (NPHIs) that aims to improve disease prevention and response, through development of stronger and better coordinated public health systems in countries where these structures are absent or not adequately supported.
Read more , Visit IANPHI Internet home page
|Vacancy Announcement for Director, IARC|
The World Health Organization (WHO) is seeking applications for the post of Director, International Agency for Research on Cancer (IARC), based in Lyon, France.
|IARC Monographs - Upcoming Meetings|
Volume 109: Ambient Air Pollution
Lyon, 8-15 October 2013
Volume 108: Some Drugs and Herbal Medicines
Lyon, 4-11 June 2013
Call for Data (closes 4 May 2013)
Call for Experts (closes 30 November 2012)
|IARC Day 2012|
IARC celebrates its now traditional IARC Day on October 23, 2012.
The theme for the day this year is Nutrition and Cancer, and IARC takes pride in welcoming two keynote speakers, Dr John D. Potter (USA, New-Zealand) and Walter C. Willett (USA) to deliver the two IARC lectures, the 20th Roger Sohier Lecture, and the 9th Richard Doll Lecture, respectively.
Both distinguished speakers will then receive the IARC Medal from the Director of the Agency, Dr Christopher P. Wild, for their career-long contribution to cancer research, in the field of nutrition, diet, and cancer.
If you would like to attend the IARC Day please contact
The presentations will be subject to interpretation into French.
Click here for a short biosketch of Drs Potter and Willett
|The Lancet - Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions|
The burden of cancer is high in every world region, concludes a study led by scientists of the International Agency for Research on Cancer (IARC) and published in The Lancet today [Tuesday, October 16].
In the study, Dr Isabelle Soerjomataram and colleagues derived the disability-adjusted life years (DALYs) for 27 cancers in 184 countries in 12 world regions. DALYs is an indicator that integrates the commonly used measures of cancer burden (incidence, mortality, and survival) with measures of disability due to cancer. DALYs is calculated by adding the time lost due to premature mortality (years of life lost, or YLL) and the duration lived with disability in survivors (years lived with a disability, or YLD).
Soerjomataram I, Lortet-Tieulent J, Parkin DM, Ferlay J, Mathers C, Forman D, Bray F.
Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions.
Lancet 2012, doi: 10.1016/S0140-6736(12)61688-2
Read IARC news , Read Lancet comment
|Launch of SPLIT web site Â– Study of HPV and precancerous lesions in the tonsil|
The International Agency for Research on Cancer (IARC) is coordinating the "Study of human Papillomavirus and precancerous Lesions In the Tonsil" (SPLIT) project, which has received a grant from Institut National du Cancer (INCa), Association pour la Recherche sur le Cancer (ARC), and Ligue contre le Cancer as part of the French "Programme d'Actions IntĂ©grĂ©es de Recherche Â– Cancers des Voies AĂ©ro-Digestives SupĂ©rieures (PAIR Â– VADS) 2011".
Head and neck surgeons and pathologists from 17 recruiting centres and biologists from 7 research laboratories across France are collaborating to address the question of the natural history of human papillomavirus (HPV) infection in the tonsil.
The SPLIT project has the potential to provide a breakthrough in the understanding of the molecular, cytological, and histological changes that accompany the onset of HPV-related and -unrelated tonsil carcinomas.
A dedicated web site, http://split.iarc.fr, presents SPLIT to the scientific community through its public interface, including objectives, news about the project, and other information. The site will also offer the SPLIT group an electronic work platform through its password-protected area.
Visit SPLIT web site
|Inauguration of the first IARC Regional Hub for Cancer Registration|
In collaboration with the Tata Memorial Centre (TMC), the International Agency for Research on Cancer inaugurated the first IARC Regional Hub for Cancer Registration at the new facilities in the Homi Bhabha block of the Tata Memorial Hospital in Mumbai, India on 1 October 2012. The plaque was unveiled by Dr C.P. Wild, Director of IARC, together with Dr R.A. Badwe, Director of TMC. The ceremony was attended by Dr A. Garg, Joint Secretary, Ministry of Health & Family Welfare in India, Dr P.K. Singh, Deputy Regional Director of the South East Asia Regional Office, and by Dr P. Rajaraman, Director of South Asia Programs, Center for Global Health, US NCI, based in Delhi.
|IARC Postdoctoral Opportunities - Section of Environment and Radiation|
Call for applications for a postdoctoral opportunity in Section of the Environment and Radiation
Deadline: 15 November 2012
|IARC Publications - IARC Monographs, Volume 100 (Package of 6 volumes A,B,C,D,E,F)|
Volume 100 compiles information on tumour sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios.
Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations.
Order at WHOPress , Monographs website
|European Cancer Observatory Launch|
The International Agency for Research on Cancer and the European Network of Cancer Registries announce the launch of the European Cancer Observatory (ECO) web site today. The ECO web site is a one-stop shop that permits unique, easy access to data on cancer incidence, prevalence, mortality and survival in 40 European countries. ECO will be a valuable tool for policy-makers, medical and research professionals as well as civil society. ECO was developed as part of the ERA-NET project EUROCOURSE, funded by the Directorate General for Research and Innovation of the European Commission in the Seventh Framework Programme and the 17 partners and subcontractors of the project.
The ECO web site allows accessing, analysing and downloading European cancer data from its three component platforms: EUCAN, EUREG and EUROCIM.
Read more , Visit ECO web site
|A Low-dose ionizing diagnostic radiation to the chest at young age may increase risk of breast cancer in BRCA1/2 mutation carriers|
The Gene-Rad-Risk study reports that ionizing radiation delivered in the course of diagnostic procedures to the chest before age 30 may increase breast cancer risk in women who carry a mutation in the BRCA1 or BRCA2 gene. The findings of the study, coordinated by theÂ International Agency for Research on CancerÂ in Lyon, France, were published today online in the British Medical Journal.
Diagnostic radiation exposure and breast cancer risk among 1,993 BRCA1/2 mutation carriers: a retrospective cohort study (GENE-RAD-RISK).
A Pijpe, N Andrieu, DF Easton, A Kesminiene, E Cardis, et al.
BMJ 2012; 345 doi: 10.1136/bmj.e5660 (Published 6 September 2012
Read Full Text>
Read Article , Read BMJ Press Release
|World Cancer Factsheet|
Cancer Research UK and the International Agency for Research on Cancer, in the framework of the World Cancer LeadersÂ’ Summit, publish today a new world cancer factsheet.
See World Cancer Factsheet (Format A4) , (Format A3)
|IARC Publications - WHO Classification of Tumours of the Breast, Fourth Edition|
IARC WHO Classification of Tumours, No 4
Lakhani, S.R., Ellis. I.O., Schnitt, S.J., Tan, P.H., van de Vijver, M.J.
This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner.
Order at WHOPress
|World Hepatitis Day - 28 July 2012|
The International Agency for Research on Cancer is proud to support the World Hepatitis Day, July 28, 2012!
World Hepatitis Day is an annual event that each year provides international focus for patient groups and people living with hepatitis B and C. It is an opportunity around which interested groups can raise awareness and influence real change in disease prevention and access to testing and treatment.
For more information, click on the following links:
World Hepatitis Alliance
WHO World Hepatitis Day
World Hepatitis Day 2012 campaign video (English)
VidĂ©o de la Campagne de la JournĂ©e mondiale contre l'hĂ©patite 2012 (franĂ§ais)
VĂdeo de la CampaĂ±a del DĂa Mundial contra la Hepatitis 2012 (espaĂ±ol)
|Global estimates of cancer prevalence for 27 sites in the adult population in 2008.|
A paper by scientists of the International Agency for Research on Cancer (IARC) published this month in the International Journal of Cancer provides estimates of the number of adult cancer patients diagnosed between 2004 and 2008 who were still alive at the end of 2008. In this article by Dr Bray and colleagues, cancer prevalence is estimated for 27 cancers and 184 countries from sources of global incidence and absolute survival data, and presented by world region and level of development (the human development index). The global figure of almost 29 million persons living with cancer in 2008 diagnosed within the previous five years serves as an aid in determining the resource needs of patients in different regions of the world.
Bray F, Ren JS, Masuyer E, Ferlay J.
Global estimates of cancer prevalence for 27 sites in the adult population in 2008.
Int J Cancer. 2012 Jul 3. doi: 10.1002/ijc.27711. [Epub ahead of print]
With advances in early detection and treatment, cancer is evolving into a chronic condition in many higher resource countries. In terms of 5-year cancer prevalence, it is worth noting the dominance of three cancer types. Female breast cancer is the most prevalent neoplasm in the vast majority of countries globally, while cervix cancer is the most prevalent in much of Sub-Saharan Africa and Southern Asia. Prostate cancer, meanwhile, is the most prevalent cancer in the highest-resourced regions, including North America, Oceania, and Northern and Western Europe.
The figures highlight the need for longer-term care targeted at managing patients with certain frequently-diagnosed cancer types. To be of greater relevance to cancer planning, the estimation of other time-based measures of global prevalence is warranted, and these are discussed in the article.
|IARC Postdoctoral Opportunities - Section of Cancer Information|
Call for applications for a postdoctoral opportunity in the Section of Cancer Information
|IARC Meetings - 1st IARC Cancer and Society Lecture now online|
IARC Cancer and Society Lecture
"Research is necessary but not sufficient: Challenges in preventing occupational and environmental cancer"
Dr David Michaels
US Department of Labor/Occupational Safety and Health Administration, Washington, USA
28 June 2012
IARC, Lyon, France
|IARC Monographs - Upcoming Meetings|
Volume 108: Some Drugs and Herbal Medicines
Lyon, 4-11 June 2013
Volume 107: Polychlorinated biphenyls and polybrominated biphenyls
Lyon, 12-19 February 2013
Call for Data (closes 12 Jan 2013)
Request for Observer Status (closes 12 Oct 2012)
Volume 106: Trichloroethylene and some chlorinated agents
Lyon, 2-9 October 2012
Preliminary List of Agents to be Reviewed
Call for Data (closes 2 Sept 2012)
|JNCI - The Role of Cancer Research in Noncommunicable Disease Control|
The Role of Cancer Research in Noncommunicable Disease Control
Cancer control needs a targeted approach on a regional basis in order to effectively reduce the burden of disease, according to a commentary published in the Journal of the National Cancer Institute on 10 July.
J Natl Cancer Inst (2012) doi: 10.1093/jnci/djs262
Advance Access First published online: July 10, 2012
Read more , Read article - JNCI website
|Call for applications now open for IARC Fellowships|
Call for applications now open for IARC Fellowships:
- Postdoctoral Fellowship programme
- Expertise Transfer Fellowship
- Senior Visiting Scientist Award
- IARC-Australia Postdoctoral Fellowship
- IARC-Ireland Postdoctoral Fellowship
Deadline 30 November 2012
See IARC Fellowships for Cancer Research
|IARC Scientific Papers Â– Search facility|
The IARC Communications Group is pleased to announce the addition to the IARC website of a Â“Scientific Papers Â– Search facilityÂ”.
The database contains articles published in peer-reviewed journals authored by IARC staff, visiting scientists, fellows and students.
The database goes back to 2003 and will be updated on a monthly basis to incorporate new publications which have complete bibliographic citations.
Link to IARC Scientific Papers
|IARC: DIESEL ENGINE EXHAUST CARCINOGENIC|
After a week-long meeting of international experts, the International Agency for Research on Cancer (IARC), which is part of the World Health Organization (WHO), today classified diesel engine exhaust as carcinogenic to humans (Group 1), based on sufficient evidence that exposure is associated with an increased risk for lung cancer.
Read IARC Press Release 213
Leer IARC Nota de Prensa 213
Watch Videocast, Dr C Portier, Chair, Monographs Meeting Volume 105
Watch Videocast, Dr C Wild, IARC Director
Listen Podcast, Dr N Gaudin, Head, IARC Communications Group
Read Backgrounder Read Frequently Asked Questions
Visit Meeting Volume 105 information page
|Questions and Answers - IARC Monographs Meeting: Diesel and gasoline engine exhausts and some nitroarenes|
IARC Monographs Meeting: Diesel and gasoline engine exhausts and some nitroarenes (5-12 June 2012.
Questions and Answers on IARC Monographs Meeting - Volume 105
Read more , Visit Meeting Volume 105 information page
|IARC Monographs Meeting: Diesel and gasoline engine exhausts and some nitroarenes (5-12 June 2012)|
The Monographs Programme of the International Agency for Research on Cancer is about to proceed with the evaluation of the human carcinogenicity of Diesel and gasoline engine exhausts and some nitroarenes (5-12 June 2012).
The below documents serve to highlight the upcoming meeting and to provide a short briefing on the processes followed for Monograph meetings.
Preliminary List of Participants
Preliminary List of Agents to be Reviewed
Call for Data (closes 5 May 2012)
Call for Experts (closed 31 Aug 2011)
Request for Observer Status (closed 5 Feb 2012)
WHO Declaration of Interests for this volume
Read Backgrounder , Read Frequently asked questions
|IARC Postdoctoral Opportunities - Section of Environment and Radiation - Deadline: 01/07/2012|
Call for applications for a postdoctoral opportunity in the Section of Environment and Radiation.
|The Lancet Oncology - Global cancer transitions according to the Human Development Index (2008Â–2030): a population-based study|
"Human development central to changing cancer burden" - Such is the conclusion of a study led by scientists of the International Agency for Research on Cancer (IARC) and published Friday 1 June 2012 in the Lancet Oncology. Strikingly the study demonstrates not only how an increasing cancer burden will fall predominantly on those countries that are in the process of social and economic transition but also that the type of cancers that are most common is changing.
Global cancer transitions according to the Human Development Index (2008Â–2030): a population-based study.
F Bray, A Jemal, N Grey, J Ferlay, D Forman
Published Online June 1, 2012 DOI:10.1016/S1470-2045(12)70211-5
Read article , IARC Press Release 212
|World No Tobacco Day 2012|
Tobacco industry interference is the theme of this yearÂ’s World No Tobacco Day, which takes place on 31 May 2012. The campaign will focus on the need to expose and counter the tobacco industry's brazen and increasingly aggressive attempts to undermine global tobacco control efforts.
|Quote of the week|
Â“(Â…) Science makes the breakthroughs. Public health operationalizes them and leaps ahead.Â”
Dr Margaret Chan
Director-General of the World Health Organization
Address to the Sixty-fifth World Health Assembly
21 May 2012
|First signs of a levelling off in incidence trends in malignant melanoma in younger generations|
A paper by scientists of the International Agency for Research on Cancer (IARC) published on May 21 in the International Journal of Cancer analysed incidence trends in malignant melanoma worldwide and observed first signs of a levelling off in younger generations.
International trends in the incidence of malignant melanoma 1953Â–2008 - are recent generations at higher or lower risk?
F Erdmann, J Lortet-Tieulent, J SchĂĽz, H Zeeb, R Greinert, E W. Breitbart, F Bray
Int. J. Cancer. doi: 10.1002/ijc.27616
Read more , Read article
|Infections cause one in six of all cancers worldwide: IARC|
Worldwide, 2 million (16.1%) of the total 12.7 million new cancer cases in 2008 are attributable to infections. This fraction is higher in less developed countries (22.9%) than in more developed countries (7.4%) and varies 10-fold by region from 3.3% in Australia and New Zealand to 32.7% in sub-Saharan Africa, according to a landmark study of infection-related cancers published today in The Lancet Oncology.
Global burden of cancers attributable to infections in 2008: a review and synthetic analysis.
C de Martel, J Ferlay, S Franceschi, J Vignat, F Bray, D Forman, M Plummer.
Lancet Oncology, Published online May 9, 2012
Read more , Read article
|IARC Latin America Collaboration Meeting Statement|
At the initiative of the International Agency for Research on Cancer (IARC), leaders of national cancer centres from 16 Latin American countries and representatives of regional and international partners met in Lyon on 26 and 27 March 2012, to discuss the current status of research on cancer prevention and control in the region and propose avenues for progress. After the meeting,Â the participants formulated a statementÂ of initiatives across the continent, spanningÂ cancer registration,Â research on cancer etiology, screening and immunization, as well asÂ education and training of cancer research scientists. These initiatives shouldÂ maximize the effectiveness of the AgencyÂ’s research strategy, through their alignment and integration with the needs and priorities for cancer prevention and control in Latin America.
|BMJ - Long-term opium use in Iran associated with higher risk of premature death|
Long-term opium use, even at moderately low levels, is associated with increased risks of several causes of death, according to a study of more than 50 000 adults in Iran, published today in the British MedicalJournal(BMJ).
Opium use and mortality in Golestan Cohort Study: prospective cohort study of 50 000 adults in Iran.
H Khademi, R Malekzadeh, A Pourshams, E Jafari, R Salahi, S Semnani, B Abaie, F Islami, S Nasseri-Moghaddam, A Etemadi, G Byrnes, C C Abnet, S M Dawsey, N E Day, P D Pharoah, P Boffetta, P Brennan, F Kamangar.
BMJ 2012; 344 doi: 10.1136/bmj.e2502
Read more , Read article
|New breast cancer susceptibility gene found|
Currently, only about 30% of the familial risk of breast cancer has been explained, leaving the substantial majority still unaccounted for. In a large collaborative study led by Professor Melissa Southey at the University of Melbourne and Associate Professor Sean Tavtigian and Professor David Goldgar at the University of Utah, we found that mutations in a gene called XRCC2, although rare, explain another proportion of breast cancers that run in families where there is no known genetic cause and that particularly occur at an early age.
Rare Mutations in XRCC2 Increase the Risk of Breast Cancer
D.J. Park, F. Lesueur, T. Nguyen-Dumont, M. Pertesi, F. Odefrey, F. Hammet, S.L. Neuhausen, E.M. John, I.L. Andrulis, M.B. Terry, M. Daly, S. Buys, F. Le Calvez-Kelm, A. Lonie, B.J. Pope, H. Tsimiklis, C. Voegele, F.M. Hilbers, N. Hoogerbrugge, A. Barroso, A. Osorio, the Breast Cancer Family Registry, the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, G.G. Giles, P. Devilee, J. Benitez, J.L. Hopper, S.V. Tavtigian, D.E. Goldgar, M.C. Southey.
The American Journal of Human Genetics, Volume 90, Issue 4, 734-739, 29 March 2012. doi:10.1016/j.ajhg.2012.02.027
Read more , Read article
|IARC Scientific Publication No 163 - Molecular Epidemiology: Principles and Practices|
Molecular Epidemiology: Principles and Practices
IARC Scientific Publication No 163
Edited by Nathaniel Rothman, Pierre Hainaut, Paul Schulte, Martyn Smith, Paolo Boffetta and Frederica Perera.
This book captures the fascinating developments and provides an extended, forward-looking vision of the principles, practice and impact of Molecular Epidemiology. Written and coordinated by world leaders in the field, the book covers, in a systematic way, the major conceptual advances, with a strong emphasis on study design and on how to incorporate biomarker studies into epidemiology practice.
Read more , Order at WHO Press
|IARC Monographs - List of Classifications by Cancer Site|
We are pleased to announce the publication of a list of carcinogenic agents - by cancer site - with sufficient or limited evidence in humans. The list will be updated regularly as new classifications are announced.
See List of Classifications by Cancer Site , IARC Monographs website
|IARC Latin America Collaboration|
The directors of national cancer institutions from 15 Latin American countries (see list below), met in Lyon on the 26 and 27 March 2012 under the initiative of the International Agency for Research on Cancer (IARC), to discuss the current status of research on cancer prevention and control in the region.
Read IARC Press Release 211 , Spanish version
|The Lancet - Cancer mortality in India: a nationally representative survey|
This landmark study, as well as providing a unique snapshot of the current Indian situation with respect to cancer mortality, paves the way for other emerging economies to implement similar systems in settings where the civil death registration systems (CRS) are either non-existent or too weak to provide reliable information on the numbers and causes of deaths.
Cancer mortality in India: a nationally representative survey.
R Dikshit, P C Gupta, C Ramasundarahettige, V Gajalakshmi, L Aleksandrowicz, R Badwe, R Kumar, S Roy, W Suraweera, F Bray, M Mallath, P K Singh, D N Sinha, A S Shet, H Gelband, P Jha, for the Million Death Study Collaborators
The Lancet, Early Online Publication, 28 March 2012 doi:10.1016/S0140-6736(12)60358-4
Read article , IARC Press Release 210
|El Espectador - Una vez mĂˇs la salud en crisis|
Interview of Dr Chris Wild for the Colombian newspaper El Espectador: Health in crisis, once again.
Read more (available only in Spanish) , Website El Espectador
|Launch of InterCHANGE website: The study of head and neck cancers in Latin America|
The International Agency for Research on Cancer (IARC) is the coordinating centre for a recently launched study of head and neck cancers in Latin America (InterCHANGE). The main focus of the study is to investigate genetic, infectious and lifestyle factors in the onset and outcome of head and neck cancers in the region. The study is currently under way in multiple centres in Brazil as well as Argentina, and additional partners are envisaged.
A dedicated website, http://interchange.iarc.fr, presents InterCHANGE to the scientific community through its public interface, including objectives, a description of the study, a list of collaborators and dates and venues of upcoming meetings. A protected area contains pertinent information for the recruiting centres, such as protocol, questionnaires and minutes of the InterCHANGE meetings.
Centres interested in learning more about InterCHANGE and the possibility of joining the consortium should contact the project coordinator Dr Paul Brennan at: firstname.lastname@example.org
Link to InterCHANGE website
|The Interphone Study|
The Interphone study - a set of multi-national caseÂ–control studies coordinated by the International Agency for Research on Cancer, focusing on the possible relationship between radiofrequency electromagnetic fields as emitted during the use of mobile phones and the risk of four types of tumours of the head and neck region, namely brain tumours (glioma and meningioma), acoustic neurinoma and parotid gland tumours Â– has now been formally completed, with the main scientific publications in 2010 and 2011 and the final report made public today. The international study group continues working together using the study base to identify other possible risk factors for those tumours, including some lifestyle factors, occupational exposures, medical conditions and examinations, or certain environmental exposures.
More details and the final report on mobile phones can be found here.
Link to The Interphone Study website
|European Urology - International Variation in Prostate Cancer Incidence and Mortality Rates|
Prostate cancer is the most commonly diagnosed cancer among men in many regions of the world, with 899 000 new cases and 258 000 new deaths recorded in 2008. The burden from the disease is anticipated to increase to 1.7 million new cases and 499 000 deaths by 2030 were the respective incidence and mortality rates of prostate cancer to remain unchanged in the future.
This collaborative study led by Ahmedin Jemal of the American Cancer Society and Freddie Bray of the International Agency for Research on Cancer observed that prostate cancer incidence rates increased in 32 of the 40 countries examined during the most recent decade, while prostate cancer mortality rates declined during the same period in 27 of the 53 countries included in the analysis.
International Variation in Prostate Cancer Incidence and Mortality Rates
M M Center, A Jemal, J Lortet-Tieulent, E Ward, J Ferlay, O Brawley, F Bray
European Urology, Early online publication 15 March 2012, DOI:10.1016/j.eururo.2012.02.054
Read article , IARC Press Release 209
|IARC Postdoctoral Opportunities|
Call for applications for a postdoctoral opportunity in the Section of Nutrition and Metabolism/Nutritional Epidemiology Group.
|Industry group Â“threatensÂ” journals to delay publications of important study on diesel engine exhaust|
The Lancet Oncology reports today on an industry group "threatening" journals to delay publications that may be relevant for the forthcoming IARC Monographs meeting onÂ Diesel and gasoline engine exhausts and some nitroarenes (Vol. 105, 5-12 June, 2012).
Read more , The Lancet Oncology home page
|World Cancer Day 2012. Together it is possible|
Each year on 4 February, World Cancer Day, WHO and the International Agency for Research on Cancer (IARC) support the Union for International Cancer Control (UICC) to promote ways to ease the global burden of cancer. Preventing cancer and raising quality of life for cancer patients are recurring themes. WHO and IARC will focus this year on screening and vaccination.
"Together it is possible" is the 2012 theme for World Cancer Day, reinforcing that it is only by every person, organization, and government individually doing their part that the world will be able to reduce premature deaths from cancer and other noncommunicable diseases.
|Launch of EPI-CT website|
The International Agency for Research on Cancer (IARC) is the coordinating centre of Â“Epidemiological study to quantify risks for paediatric computerized tomography and to optimize doses (EPI-CT)", an international project supported by the European Union. The EPI-CT study uses cohort data from nine European countries: Belgium, Denmark, France, Germany, the Netherlands, Norway, Spain, Sweden, and the United Kingdom: 1 million patients will be enrolled. The study aims to evaluate the factors associated with the use of paediatric CT scans, to build evidence to understand risks vs benefits of CT procedures and to define strategies for dose reduction.
A dedicated website, http://epi-ct.iarc.fr is the public interface of the study.
Visit EPI-CT website
|Launch of HPV-AHEAD website|
The International Agency for Research on Cancer (IARC) coordinates a study entitled Â“Role of human papillomavirus infection and other co-factors in the aetiology of head and neck cancer in Europe and IndiaÂ” (HPV-AHEAD) that has recently received a grant by the Seventh Framework Programme (FP7) of the European Commission in the Cooperation Work Programme: Health 2011. This proposal will be focused on the elucidation of the role of human papillomavirus (HPV) types and other environmental risk factors in HNC in Europe and India. Overall, the study will provide important insights for the screening, diagnosis, treatment and prophylaxis of HPV-associated HNC in Europe, India and elsewhere.
Link to the HPV-AHEAD website
|The annual Science and Wireless series hosts IARC scientist|
The annual Science & Wireless series, held in Australia, provides an opportunity for researchers, regulators, industry specialists and members of the community to meet and discuss topical issues in a public forum.
In November 2011 the event provided an opportunity to consider the implications of the International Agency for Research into Cancer (IARC)'s recent classification of Radiofrequency (RF) as 2B Â– 'possibly carcinogenic'.
|Cancer - Cancer burden in Africa and opportunities for prevention|
Cancer is an emerging public health problem in Africa. About 715,000 new cancer cases and 542,000 cancer deaths occurred in 2008 on the continent, with these numbers expected to double in the next 20 years simply because of the aging and growth of the population.
This paper reviews the current patterns of cancer in Africa and the opportunities for reducing the burden through the application of resource level interventions, including implementation of vaccinations for liver and cervical cancers, tobacco control policies for smoking-related cancers, and low-tech early detection methods for cervical cancer, as well as pain relief at the palliative stage of cancer.
Cancer burden in Africa and opportunities for prevention
A Jemal, F Bray, D Forman, M O'Brien, J Ferlay, M Center, DM Parkin.
Cancer. 2012 Jan 17. doi: 10.1002/cncr.27410. [Epub ahead of print]
|Epidemiology - Mobile Phone Use and Incidence of Glioma in the Nordic Countries 1979Â–2008: Consistency Check|
Some case-control studies have reported increased risk of glioma associated with mobile phone use. These increased risks would ultimately result in increased incidence rates of glioma over time, after a certain lag or induction period following the introduction of mobile phones. This study analyzed annual age standardized incidence rates of glioma in men and women aged 20 to 79 years in the Nordic countries from 1979-2008.
Â No clear trend change was observed in the incidence rates of glioma in the adult population of the Nordic countries during this period. Some of the higher risk increases reported in case-control studies appear to be incompatible with the observed lack of incidence rate increase in middle-aged men, even when considering exposures and induction periods of up to 15 years, suggesting that biases and errors in the self-reported use of mobile phone may have distorted some of the findings. The results of this study are consistent with either the absence of any association between mobile phone use and glioma risk, with lower risks than reported from some case-control studies, or with longer induction periods than currently investigated.
I Deltour, A Auvinen, M Feychting, C Johansen, L Klaeboe, R Sankila, J SchĂĽz
Epidemiology, Published Ahead-of-Print - Last Updated: January 13, 2012, doi:10.1097/EDE.0b013e3182448295
|IARC Publications - IARC Biennial Report 2010-2011|
The Biennial Report of the International Agency for Research on Cancer (IARC) provides a summary of the activities of the Agency during the 2010/2011 biennium.
This new report describes the various activities led by the AgencyÂ’s scientists, following the Medium-Term Strategy for 2010-2014. These activities span research areas from descriptive epidemiology to cancer registration and analysis of data on cancer occurrence and trends, to basic research into the genetic and molecular aspects of cancer development to pathogenesis and prevention studies.
|Postdoctoral Fellowships: IARC-Ireland Postdoctoral Fellowship Deadline Extended|
The application period for the "IARC-Ireland postdoctoral fellowship" has been extended to 31 January 2012.