Media Centre - IARC NEWS

2014

IARC Monographs Volume 111: evaluation of of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes
31/10/2014 -
An International Agency for Research on Cancer (IARC) Working Group of international experts reviewed the available published scientific evidence and evaluated the carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes, including single-walled and multi-walled types. These assessments will be published as Volume 111 of the IARC Monographs.

A summary of the evaluations has now been published in The Lancet Oncology.
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Variation in genomic landscape of clear cell renal cell carcinoma across Europe.
29/10/2014 -
A new genomic study of renal cell carcinomas (RCCs) uncovers novel pathways and genes affected by recurrent mutations, as well as a peculiar mutational profile in Romanian cases, suggesting that the processes underlying clear cell ccRCC tumorigenesis may vary in different populations.

Variation in genomic landscape of clear cell renal cell carcinoma across Europe
G. Scelo, Y. Riazalhosseini, et al.
Nature Communications, published Oct. 29, 2014.
DOI: 10.1038/ncomms6135
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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
20/10/2014 -
A new article reviews the sources and methods used in compiling the national cancer incidence and mortality estimates in GLOBOCAN 2012, and briefly describes the key results by cancer site and in 20 large areas of the world.

J. Ferlay, I. Soerjomataram, R. Dikshit, S. Eser, C. Mathers, M. Rebelo, D.M. Parkin, D. Forman, F. Bray (2014).
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer doi:10.1002/ijc.29210 PMID:25220842 Published online 9 October 2014
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Global incidence of oesophageal cancer by histological subtype in 2012
16/10/2014 -
A new study conducted by IARC researchers estimates for the first time the worldwide incidence of oesophageal cancer by histological subsite for 2012. The results are published today in the journal Gut.

M. Arnold, I. Soerjomataram, J. Ferlay, D. Forman
Global incidence of oesophageal cancer by histological subtype in 2012.
Gut, DOI: 10.1136/gutjnl-2014-308124. Published online 16 October 2014

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Launch of new European Code Against Cancer
14/10/2014 -
The International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization (WHO), today launches the 4th edition of the European Code Against Cancer with the participation of the European Commission. Based on the best available scientific evidence, the new Code provides 12 ways to adopt healthier lifestyles and boost cancer prevention across Europe. It is the outcome of a two-year collaborative work between cancer specialists, scientists, and other experts from across the European Union (EU).
IARC Press Release 228 , Visit website
Tony McMichael (3 October 1942–26 September 2014)
29/09/2014 -
The International Agency for Research on Cancer (IARC) is deeply saddened by the passing of Professor Tony McMichael, an Australian epidemiologist and long-time collaborator of the Agency, who died on 26 September 2014, after a short illness.
Dr McMichael had been a Member (1989–1992) and Chairman (1991–1992) of the IARC Scientific Council. He was internationally eminent as an environmental epidemiologist, and pioneered and led research on health impacts of global warming.
He will be remembered by all who knew him as a warm and caring human being.
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IARC calls on countries with high stomach cancer burden to act to prevent the disease
24/09/2014 -
A new report from the International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization, urges health authorities of countries with high stomach cancer burden to include stomach cancer in their national cancer control programmes and allocate more resources to control the disease.
IARC Press Release 227
Launch of BCNet website
23/09/2014 -
The International Agency for Research on Cancer (IARC) is pleased to announce the launch of a new website dedicated to the Low- and Middle-Income Countries (LMICs) Biobank and Cohort Building Network (BCNet). The BCNet initiative provides an opportunity for LMICs to work together in a coordinated and effective manner to jointly address the many challenges in biobanking infrastructure. The establishment of BCNet is supported by several international organizations and biobanking societies, including the National Cancer Institute - Center for Global Health (NCI-CGH), ISBER, ESBB, BBMRI-ERIC, and AORTIC, which participate in the BCNet Advisory Committee, and funding support is provided by NCI-CGH. The new website will facilitate the sharing of resources (expertise, guidelines, protocols, and standard operating procedures) between BCNet members and partners, encourage the development of joint projects, and foster collaboration.
Visit the BCNet website
Planning and developing population-based cancer registration in low- and middle-income settings (as an e-Book)
09/09/2014 -
Guidelines for establishing cancer registries, from the International Agency for Research on Cancer (IARC), the World Health Organization (WHO), and the International Association of Cancer Registries (IACR), are now available free in EPUB format. IARC Technical Publication No. 43, entitled "Planning and developing population-based cancer registration in low- and middle-income settings", provides essential guidance on the key steps in planning a registry, including accessing sources of information, monitoring the quality of the data, and reporting results. IARC introduced e-books in 2013 as a new medium for the wider dissemination of the Agency's research. This publication is also available in print and PDF formats.

IARC Technical Publication No. 43
Planning and developing population-based cancer registration in low- and middle-income settings
Freddie Bray, Ariana Znaor, Patricia Cueva, Anne Korir, Rajaraman Swaminathan, Andreas Ullrich, Susan A. Wang, and Donald Maxwell Parkin (2014).
Download this free e-book in EPUB format
IARC Postdoctoral Opportunities - Section of Molecular Pathology
05/09/2014 -
A postdoctoral opportunity is available in the Section of Molecular Pathology for a candidate with an MD or PhD degree in genetics/molecular pathology who has good experience in genomic analyses of neoplasms, as well as a good publication record. Current projects include next generation sequencing to elucidate genetic pathways and intratumoral genetic heterogeneity of brain tumours.
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IARC Fellowships for Cancer Research - Call for applications now open for IARC Fellowships
03/09/2014 -
Call for applications now open for IARC Fellowships:
- Postdoctoral Fellowship programme
- Expertise Transfer Fellowship
- Senior Visiting Scientist Award
Deadline for submission of applications: 30 November 2014
See details
Ban on widely used painkiller significantly reduced incidence of renal pelvis cancer
28/08/2014 -
A new scientific study, conducted jointly by the International Agency for Research on Cancer (IARC) and the New South Wales Cancer Council, evaluates for the first time the long-term impact of the phenacetin ban on upper urinary tract cancer rates. Published today in the Australian and New Zealand Journal of Public Health, the study shows a significant reduction in renal pelvis cancer incidence rates in Australia after phenacetin was banned in 1979, especially among women. Phenacetin, a widely used analgesic, was banned in most countries from the late 1960s because it causes renal diseases and cancers of the upper urinary tract.

S. Antoni, I. Soerjomataram, S. Moore, J. Ferlay, F. Sitas, D. P. Smith, D. Forman
The ban on phenacetin is associated with changes in the incidence trends of upper urinary tract cancers in Australia.
Australian and New Zealand Journal of Public Health, DOI: 10.1111/1753-6405.12252. Published online 28 August 2014

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Launch of IARC Handbooks of Cancer Prevention website
28/08/2014 -
The IARC Monographs Programme is pleased to announce the launch of the IARC Handbooks of Cancer Prevention website. The IARC Handbooks of Cancer Prevention provide evaluations of various approaches to primary and secondary cancer prevention. Previous volumes have evaluated the cancer-preventive activity of chemopreventive agents, the effectiveness of screening, and the effectiveness of tobacco control. The new website provides a comprehensive overview of the IARC Handbooks of Cancer Prevention series, with free access to PDFs of published volumes and lists of evaluations for all agents and activities evaluated so far, as well as updated Working Procedures and Guidelines for Observers for future volumes, and information about upcoming meetings.
Visit the Handbooks website
New report shows that HPV vaccine trials can be significantly shortened
25/08/2014 -
A new report from a Working Group convened by the International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization, and the United States National Cancer Institute (NCI) shows how the evaluation and licensing of prophylactic human papillomavirus (HPV) vaccines could be significantly accelerated.
IARC Press Release 226 , IARC Working Group Report 7
Breast cancer subtypes in Southern Africa
22/08/2014 -
In collaboration with the South African and Namibian national cancer registries, researchers at the International Agency for Research on Cancer (IARC) have conducted the largest scale study to date to examine subtypes of breast cancer in Africa, defined by estrogen, progesterone and, uniquely, human epidermal growth factor-2 receptor status. The study included more than 12 000 histologically confirmed breast cancer patients and benefited from multiracial populations as well as routine at-diagnosis receptor determination. The results of the study, published in Cancer Epidemiology, Biomarkers & Prevention, have important implications for research, early detection and treatment priorities for the growing burden of breast cancer in this region.

C. Dickens, R. Duarte, A. Zietsman, H. Cubasch, P. Kellett, J. SchĂĽz, D. Kielkowski, V. McCormack.
Racial comparison of receptor-defined breast cancer in Southern African women: subtype prevalence and age-incidence analysis of nationwide cancer registry data.
Cancer Epidemiology, Biomarkers & Prevention (2014); doi:10.1158/1055-9965.EPI-14-0603, Published online 20 August 2014.
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Guy Blaudin de Thé (5 May 1930-7 August 2014)
11/08/2014 -
The International Agency for Research on Cancer (IARC) is deeply saddened by the passing away of Professor Guy Blaudin de Thé, at the age of 84.
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IARC Postdoctoral Opportunities - Section of Cancer Surveillance
31/07/2014 -
A postdoctoral opportunity is available within the Section of Cancer Surveillance (CSU) to work on a project that is fundamental in setting priorities in cancer control planning, by quantification of the contribution of various risk factors to the global burden of cancer, thereby assessing the potential for prevention.
Deadline: 15 September 2014
Read more , Visit CSU web pages
IARC Postdoctoral Opportunities - Section of Cancer Surveillance
17/07/2014 -
A postdoctoral opportunity is immediately available within the Section of Cancer Surveillance (CSU) to work on a project which is a critical response in support of policies that combat the rising cancer burden projected over the next decades, notably in lower resource settings and among the elderly worldwide.
Deadline: 15 September 2014
Read more , Visit CSU web pages
IARC Monographs Volume 110: evaluation of five chemicals
11/07/2014 -
The International Agency for Research on Cancer (IARC) recently assessed the carcinogenicity of five chemicals: perfluoro-octanoic acid, tetrafluoroethylene, dichloromethane, 1,2-dichloropropane, and 1,3-propane sultone.

A Working Group composed of 20 international experts reviewed the available published scientific evidence and classified 1,2-dichloropropane as Group 1 (carcinogenic to humans). The experts concluded that there is now sufficient evidence that exposure to 1,2-dichloropropane causes cancer, based on studies investigating biliary tract cancers in exposed workers in the offset colour proof-printing section of a small printing company in Japan.
Tetrafluoroethylene, dichloromethane and 1,3-propane sultone were all upgraded from Group 2B (possibly carcinogenic to humans) to Group 2A (probably carcinogenic to humans). The experts also classified perfluoro-octanoic acid as Group 2B (possibly carcinogenic to humans).

A summary of the evaluations has now been published in The Lancet Oncology.
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IARC Postdoctoral Opportunities - Section of Genetics/Genetic Epidemiology Group
26/06/2014 -
A postdoctoral opportunity is immediately available within the Genetic Epidemiology Group (GEP) to work on large cohort study concerning lifestyle risk factors and both cancer specific and all cause mortality.
Read more , Visit GEP web pages
New release of EPIC website
19/06/2014 -
The International Agency for Research on Cancer (IARC), Imperial College London (ICL), and the European Prospective Investigation into Cancer and Nutrition (EPIC) collaborating centres are pleased to announce the launch of a new, updated EPIC website. The EPIC study is one of the largest cohort studies in the world, with more than half a million participants recruited across 10 European countries and followed for almost 15 years. The new site includes the EPIC access policy and research on topics such as alcohol consumption and cancer incidence, genetic predisposition to lung cancer, and the role of vitamin D in colorectal cancer prevention.
Visit the EPIC website
Launch of PRECAMA study website
05/06/2014 -
The PRECAMA study (Molecular Subtypes of Premenopausal Breast Cancer in Latin American Women) is a large, multicentre case-control study that aims to advance the prevention and management of breast cancer in countries in epidemiological transition in Latin America, through a better understanding of the molecular, pathological, and risk factor patterns. Women recruited from four Latin American countries (Chile, Colombia, Costa Rica, and Mexico) complete questionnaires on lifestyle, diet, and environmental factors and provide biological specimens that will be used for research purposes. The study is unique as it is the first to study specific genetic factors in the Latin American population that may be associated with specific subtypes of breast cancer as well as with specific lifestyle and dietary habits.
Visit website
Update of Cancer Incidence in Five Continents (CI5) websites
27/05/2014 -
The Cancer Incidence in Five Continents (CI5) websites have now been redesigned and updated with full integration of the data from CI5 Volume X. CI5 I-X presents the data published in all 10 volumes of the series in a standardized format, while CI5plus contains annual incidence time series data for selected cancer registries, now extended to 2007. CI5 X contains the detailed data from Volume X.

Visit CI5 websites
IARC and Lalla Salma Foundation sign new partnership
27/05/2014 -
The International Agency for Research on Cancer (IARC) and the Lalla Salma Foundation (LSF) have signed a new agreement to promote cancer research in Morocco and support the countryÂ’s national cancer prevention and control plans.

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IARC/WHO and IACR launch new guidelines for planning and developing cancer registries in low- and middle-income settings
26/05/2014 -
The International Agency for Research on Cancer (IARC), the World Health Organization (WHO), and the International Association of Cancer Registries (IACR) today launch new guidelines for establishing cancer registries. The publication, titled “Planning and developing population-based cancer registration in low- and middle-income settings”, provides essential guidance on the key steps in planning a registry, including accessing sources of information, monitoring the quality of the data, and reporting results.
IARC Press Release 225 , IARC Technical Publication 43
Launch of ICD-O-3 online resource
16/05/2014 -
The International Classification of Diseases for Oncology (ICD-O) is internationally recognized as the definitive classification of neoplasms. The third edition of ICD-O (ICD-O-3) and its 2011 update (ICD-O-3 First Revision, or ICD-O-3.1) have now been made available by the International Agency for Research on Cancer as online, fully searchable electronic resources. An efficient search tool enables the user to quickly identify specific entities. In addition, the listings are enhanced with useful definitions of entities from the WHO/IARC Classification of Tumours series and other sources.
Visit website
IARC Publications - WHO Classification of Tumours of Female Reproductive Organs. Fourth Edition
02/05/2014 -
IARC WHO Classification of Tumours, No 6
Robert J. Kurman, Maria Luisa Carcangiu, C. Simon Herrington, Robert H. Young

WHO Classification of Tumours of Female Reproductive Organs is the sixth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome.

Order at WHOPress
Call for proposals: Transnational Access to Large Prospective Cohorts in Europe
30/04/2014 -
The Biobanking and Biomolecular Research Infrastructure – Large Prospective Cohorts (BBMRI-LPC) FP7 project brings together large prospective cohort studies across Europe to facilitate collaborative transnational research projects. BBMRI-LPC constitutes a large network of 20 European cohort studies, involving more than 1 million study participants with lifestyle information and biospecimens collected at baseline. Within the project, the Genetic Epidemiology and Dietary Exposure Assessment Groups at the International Agency for Research on Cancer (IARC) are involved in organizing access to these unique collections for European scientists.
IARC is pleased to announce that the first call for proposals for gaining free access to these resources is now open. Applications will be accepted until 15 July 2014.

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Building capacity for sustainable research programmes for cancer in Africa
23/04/2014 -
According to an article published in Nature Reviews by a panel of international experts, cancer research in Africa will have a pivotal role in cancer control planning in this continent. The next steps required to create sustainable and impactful research programs there will enable evidenced-based cancer control approaches and planning at the local, regional and national levels.

I. Adewole, D.N Martin, M.J. Williams, C. Adebamowo, K. Bhatia et al.
Building capacity for sustainable research programmes for cancer in Africa.
Nature Reviews Clinical Oncology (2014), doi:10.1038/nrclinonc.2014.37, Published online 11 March 2014.

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Barriers to early breast cancer diagnosis in the South African setting
17/04/2014 -
Researchers at the Chris Hani Baragwanath Academic Hospital, South Africa, and IARC quantify the association between geographical access to health care and more advanced stage at breast cancer diagnosis, a strong prognostic indicator. In a peri-urban South African setting, women living beyond 20 km from the hospital had a considerably later stage at diagnosis, a shorter distance than previously thought. This effect was more pronounced in an underrepresented group of patients over the age of 70. Targeting efforts for early diagnosis of breast cancer in these women could improve diagnostic stage and help reduce the number of lives taken by breast cancer in these settings. This study is published in the International Journal of Cancer.

C. Dickens, M. Joffe, J. Jacobson, F. Venter, J. SchĂĽz, H. Cubasch, V. McCormack
Stage at breast cancer diagnosis and distance from diagnostic hospital in a periurban setting: A South African public hospital case series of over 1,000 women.
Int J Cancer. doi: 10.1002/ijc.28861. [Article first published online: 7 APR 2014]

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IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism / Biomarkers Group
07/04/2014 -
A postdoctoral opportunity is immediately available within the Group to apply metabolomic methodologies based on high performance liquid chromatography and high-resolution mass spectrometry to the discovery of new biomarkers of exposure related to cancer risk. The postdoctoral fellow will work in an innovative, well-equipped and scientifically stimulating environment. The research proposed is part of national and international projects involving leading research groups in the fields of cancer epidemiology and funded by the European Project EurocanPlatform (http://www.eurocanplatform.eu/).
Deadline: 15 May 2014
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IARC Working Group Report No 7: Primary End-points for Prophylactic HPV Vaccine Trials
01/04/2014 -
The potential of the current licensed preventive virus-like particle human papillomavirus (HPV) vaccines to have a major public health impact is leading to additional clinical trials.

The International Agency for Research on Cancer (IARC)/United States National Cancer Institute (NCI) Expert Meeting of September 2013 brought together a Working Group composed of experts from the non-profit public and academic sectors who possessed a wide range of expertise relevant to HPV vaccines. The Working Group reviewed the scientific evidence as to whether it might be appropriate to use a virological end-point, rather than a disease end-point such as cervical intraepithelial neoplasia of grade 2 or worse (CIN2+), as the primary end-point for some future clinical efficacy trials, and the circumstances under which immunobridging trials might be sufficient for licensure. Virological end-points could accelerate vaccine evaluation and licensure.

The Working Group developed recommendations for clinical trial primary end-points that could also include post-trial follow-up recommendations.

Read the Report
IARC Meetings - Emerging Issues in Head and Neck Cancer and Emerging Oncogenic Viruses: DEADLINE EXTENDED FOR EARLY REGISTRATIONS
30/03/2014 -
Early Registrations have been extended for the following two IARC Meetings:
Emerging Issues in Head and Neck Cancer
2-3 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy
Registration Deadline Extended until 17 April

Emerging Oncogenic Viruses
4-8 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy
Registration Deadline Extended until 7 April.


To register: Emerging Issues in Head and Neck Cancer , Emerging Oncogenic Viruses
The African Breast Cancer - Disparities in Outcomes study
28/03/2014 -
The African Breast Cancer - Disparities in Outcomes (ABC-DO) study is a multi-country sub-Saharan African study of determinants of breast cancer outcomes. The number of women diagnosed with breast cancer per year is rising rapidly in Africa, and the consequences of poor survival are worsened by the young age of women affected. ABC-DO will recruit women from four public hospitals in Nigeria, Uganda, South Africa, and Namibia and examine the full journey of breast cancer patients, both pre- and post-diagnosis, in order to identify modifiable determinants of survival, to be able to prevent avoidable deaths from breast cancer in African women.

Visit website
Modelling mutational landscapes of human cancers
27/03/2014 -
A new report by investigators from the International Agency for Research on Cancer (IARC) describes how key aspects of cancer development can be modelled in cultured cells treated with carcinogenic chemicals. This first-of-its-kind study uses innovative genomics and bioinformatics approaches to establish specific mutation fingerprints left in the cellular DNA by carcinogens during cellular immortalization and clonal expansion, two characteristics of cancer development. The study was published today in the Nature Publishing GroupÂ’s Scientific Reports.

Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallée MP, McKay J, Nedelko T, Muehlbauer KR, Marusawa H, Alexander J, Hazelwood L, Byrnes G, Hollstein M, Zavadil J.
Modelling mutational landscapes of human cancers in vitro. Scientific Reports (NPG). 4:4482; published on 27 March 2014; DOI:10.1038/srep04482.
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Relaunch of the IARC Handbooks of Cancer Prevention
11/03/2014 -
The IARC Monographs Programme is proud to announce the relaunch of the IARC Handbooks of Cancer Prevention. The IARC Handbooks programme was launched in 1995 to complement the IARC Monographs by providing evaluations of approaches to cancer prevention. The first 14 volumes evaluated the cancer-preventive activity of chemopreventive agents and of preventive actions, the effectiveness of screening, and the effectiveness of tobacco control.

Volume 15 will evaluate Breast Cancer Screening. Breast cancer is the most common cancer in women worldwide, in both developed and developing countries, and the potential role of primary prevention is limited because most risk factors for breast cancer are directly linked with endogenous hormone levels and reproductive choices. Therefore, secondary prevention encompassing all forms of screening for breast cancer is a priority. In 2002, an IARC Working Group developed IARC Handbook Volume 7 on Breast Cancer Screening. Today, an up-to-date, objective, and independent evaluation of the benefits and harms of all modalities of screening in different age groups and different settings is urgently needed.

IARC Handbooks of Cancer Prevention Vol. 15: Breast Cancer Screening (11-18 November 2014)
Call for Data (closing date 15 October 2014)
Call for Experts (closing date 31 March 2014)
Request for Observer Status (closing date 11 July 2014)
WHO Declaration of Interests for this volume

Read more , See brochure
IARC welcomes visitors from Inje University, Republic of Korea
25/02/2014 -
The International Agency for Research on Cancer (IARC) is pleased to welcome 21 students and faculty from the Global Health Research Center of Inje University, Republic of Korea.

The students will meet with Dr Christopher Wild, Director of IARC, and Dr Eduardo Seleiro, who will provide an overview of the Agency′s research activities and present the latest cancer trends.

Cancer is a leading cause of death in the Republic of Korea, which has been an IARC Participating State since 2006. Seven postdoctoral researchers from the country have been trained at the Agency so far.

The Agency also has a number of partnerships with the Republic of Korea and is currently setting up a large study on gastric cancer prevention integrated into the national gastric cancer screening programme.

In early March, Dr Wild will visit the Republic of Korea to attend the 5th meeting of the Asian National Cancer Centres Alliance (ANCCA).

More information about the meeting
IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism /Nutritional Epidemiology Group
19/02/2014 -
Call for applications for a postdoctoral opportunity within the Section of Nutrition and Metabolism / Nutritional Epidemiology Group.

A postdoctoral opportunity (biostatistician/epidemiologist) is available from April 2014 within the Group to work on the identification of dietary and lifestyle determinants in the occurrence of multi-morbidity, here defined as the occurrence of more than one non-communicable disease (cancer, cardio-vascular disease or diabetes).
Deadline: 31 March 2014
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World Cancer Report 2014 - Prevention is Crucial
14/02/2014 -
On 3 February 2014, the International Agency for Research on Cancer (IARC) released World Cancer Report 2014, a collaboration of over 250 leading scientists from more than 40 countries, describing multiple aspects of cancer research and control.
In a new video, the IARC Director, Dr Christopher P. Wild, presents key messages of the Report, emphasizing the need for prevention to address the alarming rise in cancer burden globally. About half of all cancers could be avoided if current knowledge was adequately implemented.
Watch the video , Read IARC Press Release 224
IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism/Nutritional Epidemiology Group -
12/02/2014 -
A postdoctoral opportunity is available immediately within the Nutritional Epidemiology Group for a biostatistician to work on an integrated approach to combine self-reported and biomarker estimates of dietary exposure, with the aim of exploring the misclassification inherent in these measurements.
Deadline 31 March 2014
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Senior Visiting Scientist Award 2013
10/02/2014 -
The recipients of the 2013 highly competitive Senior Visiting Scientist Award, currently at IARC, are:

Professor Leticia M. Fernandez Garrote from the National School of Public Health, Havana, Cuba,

Professor John D. Groopman from the Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA,

Professor Groesbeck P. Parham from the Center for Infectious Disease Research in Zambia (CIDRZ) Cervical Cancer Prevention Programme, Lusaka, Zambia (an affiliate of University of North Carolina, Chapel Hill, NC, USA), and

Professor Christopher J. Portier Senior Collaborating Scientist, Environmental Defense Fund, New York, USA.

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World Cancer Day 2014
04/02/2014 -
As every year on 4 February, World Cancer Day, the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC) support the Union for International Cancer Control (UICC) in promoting ways to reduce the global burden of cancer. The theme of World Cancer Day 2014 is “Debunk the Myths”.

On 4 February, IARC will host the 2nd IARC Cancer and Society Lecture, featuring Prof. Sir Michael G. Marmot. The title of Professor Marmot’s talk is “Fair society, healthy lives” (See Programme).

See links to WHO , UICC
Global battle against cancer wonÂ’t be won with treatment alone. Effective prevention measures urgently needed to prevent cancer crisis
03/02/2014 -
The International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization, is today launching World Cancer Report 2014, a collaboration of over 250 leading scientists from more than 40 countries, describing multiple aspects of cancer research and control.

Purchase World Cancer Report 2014
Read IARC Press Release 224 , Watch Footage
The Lancet - Alcohol and mortality in Russia: prospective observational study of 151 000 adults
31/01/2014 -
A paper published in The Lancet and led by scientists from the International Agency for Research on Cancer (IARC), along with colleagues from the Russian Cancer Research Centre in Moscow and Oxford University in the United Kingdom, provides strong evidence that the high and sharply fluctuating death rates in Russia are due mainly to alcohol, and particularly vodka.

The study asked 151 000 people how much vodka they drank, and then followed them for up to a decade, during which 8000 died. The researchers estimate that the 20-year risks of death at ages 35–54 years were 35% for men who had reported drinking three or more half-litre bottles of vodka a week, compared with 16% for men who had reported consuming less than half a litre a week. The corresponding risks of death at ages 55–74 years were 64% and 50%, respectively.

Dr Christopher Wild, Director of IARC, commented that these results reinforce the importance of alcohol as a cause of premature mortality in Russia. They also highlight the potential to reduce premature mortality by 25% by 2025 using measures that curb harmful alcohol consumption. Study leader Professor David Zaridze from the Russian Cancer Research Centre in Moscow added, “The significant decline in Russian mortality rates following the introduction of moderate alcohol controls in 2006 demonstrates the reversibility of the health crisis from hazardous drinking. People who drink spirits in hazardous ways greatly reduce their risk of premature death as soon as they stop.”

D Zaridze, S Lewington, A Boroda, G Scélo et al.
Alcohol and mortality in Russia: prospective observational study of 151 000 adults.
The Lancet, Early Online Publication, 31 January 2014, http://dx.doi.org/10.1016/S0140-6736(13)62247-3

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IARC Publications – IARC Biennial Report 2012–2013
28/01/2014 -
This Biennial Report of the International Agency for Research on Cancer (IARC) provides a summary of the activities of the Agency during the 2012–2013 biennium. These activities span research areas including descriptive epidemiology, cancer registration and analysis of data on cancer occurrence and trends, basic research into the genetic and molecular aspects of cancer development, pathogenesis, and prevention studies. This report demonstrates the high scientific quality of the work emanating from the Agency and the direct relevance of the findings to cancer control and prevention.
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Education and Training Programme website launched
28/01/2014 -
IARC is pleased to announce the launch of a new dedicated Education and Training Programme website, also available on mobile platforms. This serves as an online single entry point to all IARC education and training initiatives, including fellowships and courses, opportunities for Early Career Scientists, and a database that links to existing online IARC learning and training resources such as digital training manuals.
Visit website
The Lancet Oncology - International variations in childhood cancer in indigenous populations: a systematic review
27/01/2014 -
A paper, led by scientists of the Menzies School of Health Research (Australia) and the International Agency for Research on Cancer (IARC) and published in Lancet Oncology, reports for the first time the burden of cancer in indigenous children worldwide. Forty-four studies among indigenous children from three main regions were included: Native Americans (American Indians, Alaska Natives, and Hawaiians) in the USA, indigenous children from the Asia–Pacific region (Indigenous Australians, Maori, and Pacific Islanders in New Zealand and French Polynesia), and indigenous children from selected African countries. Little information was available on cancer profiles of indigenous children in some regions with large indigenous populations, such as South America and the circumpolar region (e.g. in the Saami and Nenets populations).

Compared with non-indigenous children, indigenous children had similar or lower incidences of all cancers combined, but patterns of incidence varied by country. The distribution of cancer types in indigenous children more closely reflected that of non-indigenous children within their own country, rather than of other indigenous groups. Cancer mortality rates were available only for Australia, the USA, and New Zealand, and were similar in indigenous and non-indigenous children in the USA and Australia. Cancer survival was overall lower for indigenous children.
These findings highlight the paucity of accessible information and the pressing need for cancer data by indigenous status in population-based cancer registries. The authors advocate the better measurement of cancer burden among indigenous children so that targeted programmes for cancer control can be planned and implemented.

Valery PC, Moore S, Meiklejohn J, Bray F.
International variations in childhood cancer in indigenous populations: a systematic review.
The Lancet Oncology, Volume 15, Issue 2, Pages e90 - e103, February 2014, doi:10.1016/S1470-2045(13)70553-9
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IARC Meetings - Emerging Issues in Head and Neck Cancer and Emerging Oncogenic Viruses: REGISTRATION NOW OPEN!
15/01/2014 -
Registration is now open for the following two IARC Meetings:

Emerging Issues in Head and Neck Cancer
2-3 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy

Emerging Oncogenic Viruses
4-8 June 2014
San Pietro in Bevagna, Province of Manduria
Puglia, Italy

For both meetings, the registration deadline is 9 May 2014.
To register: "Emerging Issues in Head and Neck Cancer" , “Emerging Oncogenic Viruses”
IARC Publications - PDFs online - Effectiveness of Tax and Price Policies for Tobacco Control - IARC Handbook of Cancer Prevention Volume 14
14/01/2014 -
IARC Handbook of Cancer Prevention Volume 14

"Effectiveness of Tax and Price Policies for Tobacco Control" is now available in PDF format.

Download here
Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data.
09/01/2014 -
A paper led by scientists of the International Agency for Research on Cancer (IARC) published in the European Journal of Cancer predicts there will be 23,000 new cases of testicular cancer annually in Europe by 2025, a rise of 24% from 2005. The predictions are based on an extrapolation of recent trends in recorded incidence from high-quality population-based cancer registries in Europe using age-period-cohort models.

While testicular cancer incidence rates are increasing in most countries, signs of a transition are apparent, with stabilising rates in certain high-risk countries in Northern and Western Europe (Denmark, Germany, Austria, Switzerland and England) offset by rapid increases in incidence rates in a number of Southern European countries, including Croatia, Slovenia, Italy and Spain. The authors predict that around one in 100 men may be diagnosed with the disease annually in the highest risk countries of Europe (Croatia, Slovenia and Norway) circa 2025. The article aims to support the planning of services and prioritisation of the necessary resources in European countries, ensuring equitable management and provision of care for testicular cancer patients in the future.

Le Cornet C, Lortet-Tieulent J, Forman D, BĂ©ranger R, Flechon A, Fervers B, SchĂĽz J, Bray F.
Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data.
Eur J Cancer. 2013 Dec 23. pii: S0959-8049(13)01054-X. doi: 10.1016/j.ejca.2013.11.035. [Epub ahead of print]

Read article at EJC website , Science Direct
21st Roger Sohier Lecture - 10 January 2014
08/01/2014 -
Dr Harold Varmus, co-recipient of a Nobel Prize for studies of the genetic basis of cancer and US National Cancer Institute (NCI) Director will present the 21st Roger Sohier Lecture on 10 January at the International Agency for Research on Cancer (IARC). The title of Dr Varmus's talk is "Promoting the discovery and application of knowledge about cancer".

He will then receive the IARC Medal of Honour from the Director of the Agency, Dr Christopher P. Wild, for his career-long contribution to cancer research.

Visit NCI Director's Page
REMINDER IARC Monographs Meeting: Advisory Group to Recommend Priorities for IARC Monographs during 2015-2019
07/01/2014 -
The deadline for submitting the form to nominate agents for consideration in future IARC Monographs is Friday, January 31 2014.

Advisory Group to Recommend Priorities for IARC Monographs during 2015-2019 (7-9 April 2014)
Information on how to submit a nomination, and about the Advisory Group
Form for Nomination of Agents (closing date 31 January 2014)
Declaration of interests for individuals submitting nominations

See IARC Monographs website
In The cancer wars Lancet series, IARC Director emphasizes primary prevention as the most effective way to fight cancer
06/01/2014 -
In a piece entitled “Global cancer patterns: causes and prevention”, IARC Director Dr Christopher Wild, and long-time IARC collaborator Dr Paolo Vineis show that in view of the growing global cancer burden, primary prevention is a particularly effective –and probably also cost-effective– approach to curbing the increase: whilst between a third and half of all cancers are preventable on the basis of current knowledge, “structural interventions (including bans, taxation, and urban planning)” are needed, however, which can benefit other people, reduce shared risk factors associated with other noncommunicable diseases, and can completely remove or reduce some long-term causes of cancer.

Global cancer patterns: causes and prevention
Paolo Vineis, Christopher P Wild
The Lancet, Early Online Publication, 16 December 2013
doi:10.1016/S0140-6736(13)62224-2

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IARC Publications - IARC Monographs in PDF
05/01/2014 -
Volume 106: Trichloroethylene, Tetrachloroethylene and Some Other Chlorinated Agents
We are pleased to make available six Monographs of Volume 106. The remaining Monograph, Trichloroethylene, and the full volume will be posted shortly.

Volume 105: Diesel and Gasoline Engine Exhausts and Some Nitroarenes
We are pleased to announce that this volume of the IARC Monographs is now available on-line.

Download Volume 106 , Volume 105
IARC Monographs - Upcoming Meetings - Volume 111: Some Nanomaterials and Some Fibres
05/01/2014 -
Meeting Volume 111: "Some Nanomaterials and Some Fibres" is announced
30 September - 7 October 2014

Call for Data (closing date 3 September 2014)
Call for Experts (closing date 30 January 2014)
Request for Observer Status (closing date 3 June 2014)
WHO Declaration of Interests for this volume

See IARC Monographs website