Who's Who

Massimo Tommasino

Section and Group Head

Infections and Cancer Biology Group


Specialty:

Virology, cancer, molecular mechanisms of cellular transformation

Academic Degrees

YearDegreeMajorInstitutionTownCountry
1981DoctoratePharmacyUniversity of BariBariItaly


Current Research Projects

  • Identification of a novel mechanism of inactivation of the p53 functions
    M. Tommasino, B. Sylla, R. Accardi

  • Prevalence of HPV infections in human specimens from different anatomical sites
    M. Tommasino, T. Gheit, S. McKay-Chopin

  • Co-operation of oncogenic viruses and other co-factors in carcinogenesis
    M. Tommasino, B. Sylla, R. Accardi

  • Role of β cutaneous HPV types in skin carcinogenesis
    M. Tommasino, B. Sylla, R. Accardi, T. Gheit, S. McKay-Chopin

  • Role of human papillomavirus infection and other co-factors in the aetiology of head and neck cancer in India and Europe
    M. Tommasino (Coordinator)


Selected Publications

Cornet I, Bouvard V, Campo MS, Thomas M, Bank L, Gissmann L, Lamartine J, Sylla BS, Accardi R, Tommasino M (2012) Comparative analysis of transforming properties of E6 andE7 from different Beta human papillomavirus types J. Virol. 86 : 2366-70

Accardi R, Scalise M, Gheit T, Hussain IS, Yue J, Carreira C, Collino A., Indiveri C, Gissmann L, Sylla BS, Tommasino M (2011) IκB kinase β promotes cell survival by antagonizing p53 functions through ΔNp73α phosphorylation and stabilization. Mol. Cell. Biol. 31 : 2210-26

Viarisio D, Muellelr-Decker K, Kloz K, Aengeneyndt B, Kopp-Schneider A, Groene HJ, Gheit T, Flechtenmacher C, Gissmann L. Tommasino M (2011) E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice. PloS Pathogens 7

Cazzaniga M, Gheit T, Casadio C, Khan N, Macis D, Valenti F, Miller MJ, Sylla BS, Akiba S, Bonanni B, Decensi A, Veronesi U, Tommasino M (2009) Analysis of the presence of cutaneous and mucosal papillomavirus types in ductal lavage fluid, milk and colostrum to evaluate its role in breast carcinogenesis. Breast Cancer Res. Treat. 114 : 599-605

Rollison DE, Pawlita M, Giuliano AR, Iannacone MR, Sondak VK, Messina JL, Cruse CW, Fenske NA, Glass LF, Kienstra M, Michael KM, Waterboer T, Gheit T, Tommasino M (2008) Measures of cutaneous human papillomavirus infection in normal tissues as biomarkers of HPV in corresponding non-melanoma skin cancers. Int. J. Cancer 123 : 2337-42

Scientific Societies Membership

American Society for Microbiology
Steering Committee of the network “International Epidemiologic Study of Worldwide Distribution of Type-specific HPV DNA in Cancers of the Vulva, Vagina, Anus and Penis (HPV VVAP), Barcelona, Spain