Who's Who

Maxime Vallee

Scientist

Genetic Cancer Susceptibility Group


Academic Degrees

YearDegreeMajorInstitutionTownCountry
2012PhDBioinformaticsUCBLLyonFrance
2008EngineerBioinformaticsINSALyonFrance
2002BaccalauréatScienceLycée Alain BorneMontélimarFrance


Current Research Projects

  • Study of copy number variations in normal vs. tumor exomes.
    Maxime Vallée, James McKay

  • Design of an internet tool to assess variants of uncertain clinical significance in high-risk breast cancer genes BRCA1 and BRCA2.
    Maxime Vallée, Sean Tavtigian


Selected Publications

Maxime P Vallée, Tiana C Francy, Megan K Judkins, Davit Babikyan, Fabienne Lesueur, Amanda Gammon, David E Goldgar, Fergus J Couch, and Sean V Tavtigian (2012) Classification of missense substitutions in the BRCA genes: a database dedicated to Ex-UVs. Human Mutation vol 33 : 22-28

Noralane M Lindor, Lucia Guidugli, Xianshu Wang, Maxime P Vallée, Alvaro N A Monteiro, Sean Tavtigian, David E Goldgar, and Fergus J Couch (2012) A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS). Human Mutation vol 33 : 8-21

Marc Tischkowitz, Marinela Capanu, Nelly Sabbaghian, Lili Li, Xiaolin Liang, Maxime P Vallée, Sean V Tavtigian, Patrick Concannon, William D Foulkes, Leslie Bernstein, WECARE Study Collaborative Group, Jonine L Bernstein, and Colin B Begg (2012) Rare germline mutations in PALB2 and breast cancer risk: a population-based study. Human Mutation vol 33 : 674-680

Florence Le Calvez-Kelm, Fabienne Lesueur, Francesca Damiola, Maxime Vallée, Catherine Voegele, Davit Babikyan, Geoffroy Durand, Nathalie Forey, Sandrine McKay-Chopin, Nivonirina Robinot, Tù Nguyen-Dumont, Alun Thomas, Graham B Byrnes, Breast Cancer Family Registry, John L Hopper, Melissa C Southey, Irene L Andrulis, Esther M John, and Sean V Tavtigian (2011) Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study. Breast Cancer Research vol 13 : R6

Sean V Tavtigian, Peter J Oefner, Davit Babikyan, Anne Hartmann, Sue Healey, Florence Le Calvez-Kelm, Fabienne Lesueur, Graham B Byrnes, Shu-Chun Chuang, Nathalie Forey, Corinna Feuchtinger, Lydie Gioia, Janet Hall, Mia Hashibe, Barbara Herte, Sandrine McKay-Chopin, Alun Thomas, Maxime P Vallée, Catherine Voegele, Penelope M Webb, David C Whiteman, Australian Cancer Study, Breast Cancer Family Registries (BCFR), Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab), Suleeporn Sangrajrang, John L Hopper, Melissa C Southey, Irene L Andrulis, Esther M John, and Georgia Chenevix-Trench (2009) Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer. American Journal of Human Genetics vol 85(4) : 427–446