Who's Who

Nivonirina Robinot

Laboratory Technician

Genetic Cancer Susceptibility Group

Academic Degrees

2014Certificates towards MSc in Digital BiologyJava programing for gene expression analysis, Databases and data modelling for microarray experiments (2013-2014)University of ManchesterManchesterUK
2002BSc (First class Hons) in Applied BiologyMolecular biology, Genetics, Cancer biology, Research methods, Stem cell research, Cancer immunotherapyKingston UniversitySurreyUK
1996DUT in Applied BiologyMoleculae biology, Biology, Biochemistry, Immunology, Hematology, Microbiology, Genetic engineering, Cell cultureIUT, Université Claude BernardLyonFrance
1987DUEST in Natural SciencesBiology, Biochemistry, Geology, ChemistryUniversité d'AntananarivoAntananarivoMadagascar

Current Research Projects

  • Study on differential expression between renal tumors and normal tissues (KIDRISK) using the Illumina microarray platform
    PI: G Scelo, F LeCalvez, J McKay

  • Creation and management of a database for microarray-based differential expression data using MySQL
    PI: N Robinot, F LeCalvez

  • Case-control mutation screening and genotyping of various cancer susceptibility genes using sequencing technology
    PI: S Tavtigian, F Lesueur, F LeCalvez

Selected Publications

Park DJ, Tao K, Le Calvez-Kelm F, Nguyen-Dumont T, Robinot N, Hammet F, Odefrey F, Tsimiklis H, Teo ZL, Thingholm LB, Young EL, Voegele C, Lonie A, Pope BJ, RoaneTC, Bell R, Hu H, Shankaracharya, Huff CD, Ellis J, Li J, Makunin IV, John EM, Andrulis IL, Terry MB, Daly M, BuysSS, Snyder C, Lynch HT, Devilee P, Giles GG, Hopper JL, Feng BJ, Lesueur F, Tavtigian SV, Southey MC and Goldgar DE (2014) Rare Mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancers; 4: 804-815.

Damiola F, Pertesi M, Oliver J, Le Calvez-Kelm F, Voegele1 C, Young EL, Robinot N, Forey N, Durand G, Vallée MP,Tao K, Roane TC, Williams GJ, Hopper JL, Southey MC, Andrulis IL, John EM, Goldgar DM, Lesueur F and Tavtigian SV (2014) Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. Breast Cancer Research; 16:R58.

Voegele C, Bouchereau B, Robinot N, McKay J, Damiecki P, Alteyrac L (2013) A universal open-source Electronic Laboratory Notebook. Bioinformatics Advance Access

Le Calvez-Kelm F, Oliver J, Damiola F, Forey N, Robinot N, Durand G, Voegele C, Vallée MP, Byrnes G, Breast Cancer Family Registry, Hopper JL, Southey MC, Andrulis IL, John EM, Tavtigian SV and Lesueur F (2012) RAD51 and Breast Cancer Susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry Study; PLoS ONE. 7(12)

Le Calvez-Kelm F, Lesueur F, Damiola F, Vallée M, Guénard M, Voegele C, Babikyan D, Durand G, Forey N, McKay-Chopin S, Robinot N, Nguyen-Dumont T, Thomas A, Byrnes GB, Durocher F, Breast Cancer Family Registry, John L. Hopper, Melissa C. Southey, Irene L. Andrulis, Esther M. John, Sean V. Tavtigian (2011) Rare, Evolutionarily Unlikely Missense Substitutions in CHEK2 Contribute to Breast Cancer Susceptibility: Results from a Breast CFR Case-Control Mutation Screening Study Breast Cancer Research ; 13 :R6 : 1-12

Prizes, Honours

Pfizer Prize for the Best Performance in Biology, year 2002
Nuffield Foundation Awards for the BSc project on Stem Cell research, years 2001-2002

Roles and Responsibilities

Maintain laboratory equipment and stock

Do laboratory work using the Illumina platform and sequencing technology

Contribute to the development of IARC tools (eNotebook, SOP templates) using transferrable skills from work experience and continuous training

Provide training to undergraduate, postgraduate and postdoc fellows

Set up and validate methods, perform quality control and troubleshoot technical issues to assure high quality of data