IARC News

IARC Postdoctoral Opportunities - Section of Nutrition and Metabolism / Biomarkers Group

07/04/2014 A postdoctoral opportunity is immediately available within the Group to apply metabolomic methodologies based on high performance liquid chromatography and high-resolution mass spectrometry to the discovery of new biomarkers of exposure related to cancer risk. The postdoctoral fellow will work in an innovative, well-equipped and scientifically stimulating environment. The research proposed is part of national and international projects involving leading research groups in the fields of cancer epidemiology and funded by the European Project EurocanPlatform (http://www.eurocanplatform.eu/).
Deadline: 15 May 2014
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IARC Working Group Report No 7: Primary End-points for Prophylactic HPV Vaccine Trials

01/04/2014 The potential of the current licensed preventive virus-like particle human papillomavirus (HPV) vaccines to have a major public health impact is leading to additional clinical trials.

The International Agency for Research on Cancer (IARC)/United States National Cancer Institute (NCI) Expert Meeting of September 2013 brought together a Working Group composed of experts from the non-profit public and academic sectors who possessed a wide range of expertise relevant to HPV vaccines. The Working Group reviewed the scientific evidence as to whether it might be appropriate to use a virological end-point, rather than a disease end-point such as cervical intraepithelial neoplasia of grade 2 or worse (CIN2+), as the primary end-point for some future clinical efficacy trials, and the circumstances under which immunobridging trials might be sufficient for licensure. Virological end-points could accelerate vaccine evaluation and licensure.

The Working Group developed recommendations for clinical trial primary end-points that could also include post-trial follow-up recommendations.
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Publications

Improving Public Health Through Mycotoxin Control - IARC Scientific Publication, No 158

10/01/2013 Improving Public Health Through Mycotoxin Control
IARC Scientific Publication, No 158
Edited by JI Pitt, CP Wild, RA Baan, WCA Gelderblom, JD Miller, RT Riley and F Wu.
This book aims to sensitize the international community to the mycotoxin problem in a format that is accessible to a wide audience and is useful to decision-makers across a broad spectrum of disciplines, including agriculture, public health, marketing, and economics.
Order at WHOPress