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A new study published today in Genome Research models a first-of-its-kind approach to exploring the causes of cancer by combining cell and animal experimental studies with genome-wide sequencing of human tumours. Specific patterns of DNA mutations identified in human tumours were reproduced via in vivo and in vitro experimental studies, providing key insights into the mutagenic agents that underlie the development of cancer.
Huang MN, Yu W, Teoh WW, Ardin M, Jusakul A, Ng A, et al.
Genome-scale mutational signatures of aflatoxin in cells, mice and human tumours. Genome Res. Published online 24 July 2017. http://www.genome.org/cgi/doi/10.1101/gr.220038.116
The International Agency for Research on Cancer (IARC) hosted senior personnel of the World Healt...
The results of the recent meeting of the Advisory Group to Recommend Priorities for the IARC Mono...
The biobank of the International Agency for Research on Cancer (IARC) has been granted one of six...