A new study by scientists from the International Agency for Research on Cancer (IARC) in collaboration with international partners presents updated estimates of the global burden of oesophageal and gastric cancer by subtype for 2018. The study was published in the journal Gut.
Globally, oesophageal squamous cell carcinoma accounts for 84% of all cases of oesophageal cancer, and non-cardia gastric cancer makes up 82% of all cases of gastric cancer. This study showed that although the highest incidence rates of oesophageal squamous cell carcinoma, cardia gastric cancer, and non-cardia gastric cancer were observed in East Asia, the highest incidence rates of oesophageal adenocarcinoma were observed in northern Europe. Incidence rates of oesophageal adenocarcinoma, which was once a rare cancer, exceeded those of oesophageal squamous cell carcinoma in an increasing number of high-income countries. This development has largely been attributed to increasing levels of central obesity.
This quantification study brings together the most recent evidence from population-based cancer registries around the world and recent estimates of the global cancer burden. It provides an important evidence base for clinicians and health policy-makers to plan appropriate cancer control strategies.
Arnold M, Ferlay J, van Berge Henegouwen MI, Soerjomataram I
Global burden of oesophageal and gastric cancer by histology and subsite in 2018
Gut, Published online 30 June 2020;