Section of Evidence Synthesis and Classification

IARC Monographs Group


The IARC Monographs on the Evaluation of Carcinogenic Risks to Humans critically review and evaluate the published scientific evidence on carcinogenic hazards to which humans are exposed. These hazards include chemicals, complex mixtures, physical agents, biological agents, occupational exposures, and personal habits.

To achieve such evaluations, IARC convenes an international, interdisciplinary Working Group of expert scientists to develop each volume of the Monographs. IARC selects these experts based on their knowledge and experience and the absence of real or apparent conflicting interests. The Working Group writes a critical review of the pertinent scientific literature and an evaluation of the potential of each agent to cause cancer in humans. Agents are selected for evaluation based on (i) evidence of human exposure and (ii) some published scientific evidence of cancer-causing effects, which together combine into the potentially preventable cancer burden.

National and international health agencies use the IARC Monographs to guide and support their actions to prevent exposure to known, probable, and possible carcinogens. Accordingly, an overarching objective is to achieve the highest degree of scientific authority and trust in these evaluations.

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