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Section of Nutrition and Metabolism

Biomarkers Group

Current Research Topics

1. Discovery of novel biomarkers of exposure for dietary, environmental, and metabolic cancer risk factors

– Identify and validate, through metabolomic approaches, novel biomarkers of metabolic and environmental exposures, including obesity, diet (coffee, meats, fruit and vegetables, alcoholic beverages, dietary fibres, polyphenols) and microbiota.

– Develop novel analytical methods to measure specific biomarkers (hormones, inflammatory factors, diet) in large epidemiological studies.

– Develop Exposome-Explorer, an online knowledge database on biomarkers of exposure to cancer risk factors (diet, food constituents, contaminants, and pollutants).

2. Identification of risk factors for cancer and intermediate end-points through biomarker approaches

– Measure the exposome using untargeted and targeted metabolomic approaches in large epidemiological and/or intervention studies established in high- and low-income countries.

– Identify metabolic and environmental factors associated with different cancer outcomes (with a special focus on breast cancer and thyroid cancer) and intermediate end-points (obesity, metabolic syndrome, mammographic density).

– Identify the main determinants of concentrations of biomarkers for metabolic and environmental exposures.

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