Current Research Topics
1. Discovery of novel biomarkers of exposure for dietary, environmental, and metabolic cancer risk factors
– Identify and validate, through metabolomic approaches, novel biomarkers of metabolic and environmental exposures, including obesity, diet (coffee, meats, fruit and vegetables, alcoholic beverages, dietary fibres, polyphenols) and microbiota.
– Develop novel analytical methods to measure specific biomarkers (hormones, inflammatory factors, diet) in large epidemiological studies.
– Develop Exposome-Explorer, an online knowledge database on biomarkers of exposure to cancer risk factors (diet, food constituents, contaminants, and pollutants).
2. Identification of risk factors for cancer and intermediate end-points through biomarker approaches
– Measure the exposome using untargeted and targeted metabolomic approaches in large epidemiological and/or intervention studies established in high- and low-income countries.
– Identify metabolic and environmental factors associated with different cancer outcomes (with a special focus on breast cancer and thyroid cancer) and intermediate end-points (obesity, metabolic syndrome, mammographic density).
– Identify the main determinants of concentrations of biomarkers for metabolic and environmental exposures.