IARC News

Individual support of IARC research

25/07/2017 The International Agency for Research on Cancer (IARC) is grateful for the help we receive through individual financial contributions to build and strengthen our research activities. These funds play a valuable role in supporting the Agencys research and training programmes and in working towards the prevention of cancer worldwide.

In order to make it easier for individuals to join us in the fight against cancer, the Agency has revamped its Donations webpage, where visitors can learn more about supporting IARC research.

Ultimately, together we can understand cancer better and ensure that it is prevented, detected, and treated as early and as effectively as possible.

Let′s prevent cancer, together.
Visit the Donations webpage

Genome-scale mutational signatures of aflatoxin in cells, mice and human tumours

24/07/2017 A new study published today in Genome Research models a first-of-its-kind approach to exploring the causes of cancer by combining cell and animal experimental studies with genome-wide sequencing of human tumours. Specific patterns of DNA mutations identified in human tumours were reproduced via in vivo and in vitro experimental studies, providing key insights into the mutagenic agents that underlie the development of cancer.

Huang MN, Yu W, Teoh WW, Ardin M, Jusakul A, Ng A, et al.
Genome-scale mutational signatures of aflatoxin in cells, mice and human tumours. Genome Res. Published online 24 July 2017. http://www.genome.org/cgi/doi/10.1101/gr.220038.116
Read article , Read IARC Press Release 252

Asbestos-associated genome-wide DNA methylation changes in lung cancer

23/07/2017 A study by the International Agency for Research on Cancer (IARC) provides new evidence that asbestos exposure may induce DNA methylation changes in specific genes. IARC researchers, in partnership with the Finnish Institute of Occupational Health in Helsinki, carried out a genome-wide DNA methylation analysis of lung cancer tissue samples for which detailed asbestos exposure and clinical data were available, and compared the samples with normal lung tissue. The research, published last week in the International Journal of Cancer (IJC), provides key insights into the mechanisms associated with asbestos exposure that contribute to lung cancer. It also identifies new potential biomarkers of asbestos exposure.

Kettunen E, Hernandez-Vargas H, Cros MP, Durand G, Le Calvez-Kelm F, Stuopelyte K, et al.
Asbestos-associated genome-wide DNA methylation changes in lung cancer
Int J Cancer. 2017 Jul 19. doi: 10.1002/ijc.30897. [EPUB ahead of print]
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Publications

WHO Classification of Tumours of Endocrine Organs

28/06/2017 The WHO Classification of Tumours of Endocrine Organs is the tenth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome.

The book, prepared by 166 authors from 25 countries, contains more than 700 colour images and tables, and more than 3100 references.
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Cancer Today

ESTIMATED CANCER
INCIDENCE,
MORTALITY AND PREVALENCE
WORLDWIDE IN 2012

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