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14 March 2019

IARC Scientific Publication No. 165: Tumour Site Concordance and Mechanisms of Carcinogenesis

The International Agency for Research on Cancer (IARC) has published a new Scientific Publication that reviews the information on cancer sites and mechanistic events for the more than 100 agents classified in Group 1 (carcinogenic to humans) by the IARC Monographs Programme.

This publication is based on a systematic identification and comparison of the cancer sites observed in humans and those observed in experimental animals, as well as a compilation of mechanistic events for agents known to cause cancer in humans.

Relevant information was analysed on all the agents classified in Group 1 in IARC Monographs up to and including Volume 109, most of which were reviewed in Volume 100A–F. These reviews and analyses were discussed during a two-part Workshop on Tumour Site Concordance and Mechanisms of Carcinogenesis convened by IARC.

See IARC Scientific Publication No. 165

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